Hormonal Therapy News and Research

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Hormonal Therapy is treatment that adds, blocks, or removes hormones. For certain conditions (such as diabetes or menopause), hormones are given to adjust low hormone levels. To slow or stop the growth of certain cancers (such as prostate and breast cancer), synthetic hormones or other drugs may be given to block the body’s natural hormones. Sometimes surgery is needed to remove the gland that makes a certain hormone. Also called endocrine therapy, hormone therapy, and hormone treatment.

Tofu nutrients called isoflavones could lower heart disease risk

Researchers from the Harvard Medical School and Brigham and Women's Hospital working in collaboration have found that tofu and other plant-based proteins contain certain nutrients called isoflavones that can help those with heart disease and lower their disease risk.

23 Mar 2020

Discovery could pave way for new breast cancer drugs

Eric Prossnitz, PhD, hopes to help many of the 12% of American women who are projected to be diagnosed with breast cancer in their lifetimes.

7 Jan 2020

10-year results from clinical trial of extended letrozole therapy for women with HR+ breast cancer

In the updated results from NRG Oncology/NSABP B-42 trial through 10 years of observation, extending letrozole therapy for additional five years after five years of adjuvant endocrine therapy resulted in a statistically significant improvement in the 10-year disease-free survival (DFS) of postmenopausal women with hormone-receptor-positive breast cancer.

12 Dec 2019

Discovery of novel mechanism by which certain breast cancers can metastasize

Researchers from the Baylor College of Medicine and Harvard Medical School have found a novel mechanism to explain the resistance of certain breast cancers that spread in the major organs of the body. They hope that this would help develop new therapeutic strategies to treat the cancer.

12 Dec 2019

Radiation therapy alone found to be cost-effective for treatment of DCIS

Ductal carcinoma in-situ (DCIS) accounts for one-fifth of breast cancer cases in the United States, according to the American Cancer Society.

11 Dec 2019

Lab-grown, testosterone-producing cells could help treat hypogonadism

Researchers have managed to grow human, testosterone-producing cells, which could lead to improved treatment options for low testosterone levels.

9 Oct 2019

Understanding treatment and prognosis of male breast cancer

October is Breast Cancer Awareness Month, an annual campaign to raise awareness about the potentially-fatal disease. Breast cancer is known as an illness that affects mostly women, but about 1 percent of all breast cancers affect men, too.

7 Oct 2019

Targeted therapy slows disease progression and improves survival for prostate cancer

A new PARP-inhibitor has been shown to significantly delayed cancer progression among patients with prostate cancer who had cancer cells with faulty DNA repair genes.

2 Oct 2019

Adding targeted therapy drug to standard treatment benefits aggressive breast cancer patients

A study led by UCLA researchers found that adding ribociclib, a targeted therapy drug, to standard hormone therapy has been shown to significantly improve overall survival in postmenopausal women with advanced hormone-receptor positive/HER2- breast cancer, one of the most common forms of the disease.

29 Sep 2019

Breast cancer cells can go into sleep mode and relapse in the future

Breast cancer is one of the most aggressive types of cancers in the world. It is the commonest cause of cancer death in women worldwide, and it represented about 12 percent of all new cancer cases in 2012. Current predictions and statistics suggest that both worldwide incidence of breast cancer and related mortality are on the rise. Globally, breast cancer now represents one in four of all cancers in women.

3 Sep 2019

Electromagnetic fields may prevent spread of breast cancer cells, study finds

Electromagnetic fields might help prevent some breast cancers from spreading to other parts of the body, new research has found.

8 Aug 2019

AI-enabled device detects if targeted chemotherapy is working

A new portable device that utilizes artificial intelligence (AI) and biosensors can rapidly detect if cancer cells thrive after chemotherapy treatment.

17 Jul 2019

Sleep quality and fatigue among women with premature ovarian insufficiency

There have been studies and anecdotal reports about worsening of sleep quality and increasing fatigue among women who are near menopause or have reached menopause.

16 Jul 2019

Botulinum toxin may offer relief from chronic pelvic pain in women with endometriosis

Pelvic pain associated with endometriosis often becomes chronic and can persist (or recur) following surgical and hormonal interventions.

11 Jul 2019

Targeted therapy plus hormone therapy improves survival in premenopausal patients with advanced HR+ breast cancer

Adding the targeted therapy ribociclib to hormone therapy significantly improved overall survival (OS) in premenopausal patients with advanced hormone receptor-positive (HR+) breast cancer, according to results of the MONALEESA-7 Phase III clinical trial led by researchers at The University of Texas MD Anderson Cancer Center.

3 Jun 2019

Oral androgen receptor inhibitor improves outcomes for men with mHSPC

Enzalutamide, an oral androgen receptor inhibitor, can improve outcomes for men with metastatic hormone-sensitive prostate cancer, according to a large study presented by Christopher Sweeney, MBBS of Dana-Farber Cancer Institute's Lank Center for Genitourinary Oncology, during the American Society of Clinical Oncology Annual Meeting.

3 Jun 2019

Nearly all women treated for breast cancer suffer from health problems, finds study

Nearly all women who have been treated for non-metastatic breast cancer suffer from health problems after primary treatment.

21 May 2019

Inhibition of ribosome biogenesis as new treatment strategy for advanced cancers

Nearly ninety per cent of all cancer patient deaths are due to metastasis. A study from Uppsala University shows that a process that allows the cells to metastasize is aided by the synthesis of new ribosomes, the cell components in which proteins are produced.

8 May 2019

New method could lead to more personalized treatment of advanced prostate cancer

Researchers at Karolinska Institutet in Sweden have identified blood-based biomarkers that may determine which patients will benefit from continued hormonal therapy for advanced prostate cancer.

3 May 2019

Updated ASTRO/AUA Guideline on adjuvant and salvage radiotherapy after prostatectomy

The American Society for Radiation Oncology and the American Urological Association today announced updates to their joint clinical guideline on adjuvant and salvage radiotherapy after prostatectomy in patients with and without evidence of prostate cancer recurrence to include new published research related to adjuvant radiotherapy.

1 May 2019