Hormonal Therapy News and Research

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Hormonal Therapy is treatment that adds, blocks, or removes hormones. For certain conditions (such as diabetes or menopause), hormones are given to adjust low hormone levels. To slow or stop the growth of certain cancers (such as prostate and breast cancer), synthetic hormones or other drugs may be given to block the body’s natural hormones. Sometimes surgery is needed to remove the gland that makes a certain hormone. Also called endocrine therapy, hormone therapy, and hormone treatment.

PROfound phase III results offer new targeted treatment for metastatic prostate cancer

Results from the PROfound phase III study, funded by AstraZeneca and Merck Sharp & Dohme, open up a much-needed new treatment avenue for the more precise and effective treatment of patients with metastatic castration-resistant prostate cancer (mCRPC) whose disease has progressed with hormonal therapy.

21 Sep 2020

Adding abemaciclib to hormonal therapy reduces recurrence in patients with HR+ HER2- early breast cancer

Adding abemaciclib to hormonal therapy reduces the risk of cancer recurrence by 25% in patients with high-risk early hormone receptor positive (HR+) human epidermal growth factor receptor 2 negative (HER2-) breast cancer, according to results from a study at ESMO 2020.

21 Sep 2020

Patients with cancer and COVID-19 infection can experience blood clots

UC researchers and physicians are learning that COVID-19 impacts more than just the lungs. The list of potential issues multiplies when doctors also consider its impact on patients with other underlying conditions or the medications used to treat those conditions.

1 Sep 2020

Dartmouth receives $2.5 million to develop device for detecting tumor left behind during surgery

Dartmouth engineers have been awarded a $2.5 million grant from the National Cancer Institute, part of the National Institutes of Health, to develop and test a device--a microendoscopic electrical impedance sensing probe-- that could be used by surgeons to detect prostate cancer still left in the body during surgery.

25 Aug 2020

Non-hormonal therapy found to be effective for menopause-associated symptoms

A non-hormonal therapy to treat hot flashes and other symptoms associated with menopause was found to be effective in a recent clinical trial, according to a published study by a team of researchers including faculty from the University of Colorado School of Medicine.

6 Aug 2020

Study: Gender dysphoria can persist for years before patients undergo treatment

Gender dysphoria manifests early in childhood and can persist for years before patients undergo counseling and treatment, a Cedars-Sinai study has found.

16 Jun 2020

Studies show prognostic value for circulating tumor cells in advanced prostate and breast cancer

Menarini Silicon Biosystems, the pioneer of liquid biopsy and single cell technologies, announced today that results from a new study presented at the virtual 2020 meeting of the American Society of Clinical Oncology suggest that circulating tumor cell counts may be useful in determining long-term prognosis and guiding treatment selection in patients with metastatic castrate sensitive prostate cancer.

10 Jun 2020

Radiation and surgery do not prolong survival in newly diagnosed metastatic breast cancer

Up to now, women who present with a new diagnosis of breast cancer that is already in an advanced stage (stage IV) face an unanswered question about whether surgery and radiation to the tumor in the breast (local therapy) will prolong survival compared to the traditional treatment of systemic treatment alone.

29 May 2020

Study refutes link between anti-hormonal breast cancer therapy and rheumatoid arthritis risk

Breast cancer patients do not have an increased risk of developing rheumatoid arthritis. A Swedish cohort study has now come to this conclusion.

13 May 2020

Tofu nutrients called isoflavones could lower heart disease risk

Researchers from the Harvard Medical School and Brigham and Women's Hospital working in collaboration have found that tofu and other plant-based proteins contain certain nutrients called isoflavones that can help those with heart disease and lower their disease risk.

23 Mar 2020

Discovery could pave way for new breast cancer drugs

Eric Prossnitz, PhD, hopes to help many of the 12% of American women who are projected to be diagnosed with breast cancer in their lifetimes.

7 Jan 2020

10-year results from clinical trial of extended letrozole therapy for women with HR+ breast cancer

In the updated results from NRG Oncology/NSABP B-42 trial through 10 years of observation, extending letrozole therapy for additional five years after five years of adjuvant endocrine therapy resulted in a statistically significant improvement in the 10-year disease-free survival (DFS) of postmenopausal women with hormone-receptor-positive breast cancer.

12 Dec 2019

Discovery of novel mechanism by which certain breast cancers can metastasize

Researchers from the Baylor College of Medicine and Harvard Medical School have found a novel mechanism to explain the resistance of certain breast cancers that spread in the major organs of the body. They hope that this would help develop new therapeutic strategies to treat the cancer.

12 Dec 2019

Radiation therapy alone found to be cost-effective for treatment of DCIS

Ductal carcinoma in-situ (DCIS) accounts for one-fifth of breast cancer cases in the United States, according to the American Cancer Society.

11 Dec 2019

Lab-grown, testosterone-producing cells could help treat hypogonadism

Researchers have managed to grow human, testosterone-producing cells, which could lead to improved treatment options for low testosterone levels.

9 Oct 2019

Understanding treatment and prognosis of male breast cancer

October is Breast Cancer Awareness Month, an annual campaign to raise awareness about the potentially-fatal disease. Breast cancer is known as an illness that affects mostly women, but about 1 percent of all breast cancers affect men, too.

7 Oct 2019

Targeted therapy slows disease progression and improves survival for prostate cancer

A new PARP-inhibitor has been shown to significantly delayed cancer progression among patients with prostate cancer who had cancer cells with faulty DNA repair genes.

2 Oct 2019

Adding targeted therapy drug to standard treatment benefits aggressive breast cancer patients

A study led by UCLA researchers found that adding ribociclib, a targeted therapy drug, to standard hormone therapy has been shown to significantly improve overall survival in postmenopausal women with advanced hormone-receptor positive/HER2- breast cancer, one of the most common forms of the disease.

29 Sep 2019

Breast cancer cells can go into sleep mode and relapse in the future

Breast cancer is one of the most aggressive types of cancers in the world. It is the commonest cause of cancer death in women worldwide, and it represented about 12 percent of all new cancer cases in 2012. Current predictions and statistics suggest that both worldwide incidence of breast cancer and related mortality are on the rise. Globally, breast cancer now represents one in four of all cancers in women.

3 Sep 2019

Electromagnetic fields may prevent spread of breast cancer cells, study finds

Electromagnetic fields might help prevent some breast cancers from spreading to other parts of the body, new research has found.

8 Aug 2019