Hormone News and Research

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A hormone is a chemical released by one or more cells that affects cells in other parts of the organism. Only a small amount of hormone is required to alter cell metabolism. It is essentially a chemical messenger that transports a signal from one cell to another.

KAI Pharmaceuticals enrolls patients in Phase 1b study of KAI-4169 for treatment of SHPT

KAI Pharmaceuticals, Inc., a privately held drug discovery and development company, today announced enrollment of the first patients in a Phase 1b study of KAI-4169, a novel pharmaceutical agent being tested for the treatment of secondary hyperparathyroidism, which is a frequent and serious complication of end-stage renal disease.

27 Sep 2010

Breast cancer survivors with functional limitations more likely to die of poorer health: Study

Basic physical limitations following breast cancer treatment can have far-reaching consequences that substantially affect how long a patient lives.

27 Sep 2010

OncoGenex initiates OGX-427 Phase 2 trial for metastatic prostate cancer

OncoGenex Pharmaceuticals, Inc. announced today the initiation of a randomized, controlled, investigator sponsored Phase 2 trial of OGX-427 in men with metastatic prostate cancer.

27 Sep 2010

Researchers find stress-activating factors can control genes

Stress has become one of the major disease states in the developed world. Researchers from Dr.Klaus Hansen's group at BRIC, University of Copenhagen, have just shown that external factors can stress our cells through the control of our genes. "We found that stress-activating factors can control our genes by turning on certain genes that were supposed to be silenced.

27 Sep 2010

Study finds postmenopausal hormone therapy increases ovarian cancer risk

Compared with women who have never taken hormone therapy, those who currently take it or who have taken it in the past are at increased risk of ovarian cancer, regardless of the duration of use, the formulation, estrogen dose, regimen or route of administration, according to a study in the July 15 issue of JAMA.

27 Sep 2010

Calcitonin combination therapy may help treat osteoarthritis: Study

Tarsa Therapeutics, Inc. and Unigene Laboratories, Inc. today reported preclinical data showing that calcitonin may have synergistic effects in combination with other drugs in reducing the collagen degradation associated with osteoarthritis.

27 Sep 2010

New Concordia research links hormones with attention and learning

Feeling a little sluggish and having trouble concentrating? Hormones might be to blame according to new research from Concordia University published in the journal Brain and Cognition. The study shows that high estrogen levels are associated with an inability to pay attention and learn - the first such paper to report how this impediment can be due to a direct effect of the hormone on mature brain structures.

24 Sep 2010

Enobia announces positive results from ENB-0040 Phase II juvenile clinical trial for hypophosphatasia

Enobia Pharma today announced positive results for its Phase II juvenile clinical trial of ENB-0040 (asfotase alfa), an experimental bone-targeted enzyme replacement therapy intended for the treatment of hypophosphatasia (HPP). Hypophosphatasia is a rare, inherited, and sometimes fatal metabolic bone disease that affects individuals of all ages.

24 Sep 2010

Concerted effort yields significant progress in reducing depression, HIV/AIDS, and osteoporosis in women

A concerted effort to boost research on women's health over the last two decades has lessened the burden of disease and reduced deaths among women due to cardiovascular disease, breast cancer, and cervical cancer, says a new report from the Institute of Medicine. The effort has yielded less but still significant progress in reducing the effects of depression, HIV/AIDS, and osteoporosis on women, added the committee that wrote the report.

24 Sep 2010

Yoga, Tai Chi effective in treating fibromyalgia

This syndrome is often accompanied by fatigue, bowel disturbances, and urinary difficulty. Fibromyalgia can affect your daily activity, your sleep, and even your thinking when you're worn out and experiencing "brain fog." That's a term used by Henri Roca, MD, Medical Director at Greenwich Hospital's Center for Integrative Medicine in Cos Cob, Connecticut.

24 Sep 2010

Scientists find high levels of stress hormone in chronic alcoholics

Scientists at the University of Liverpool have found that high levels of a stress hormone in recovering alcoholics could increase the risk of relapse.The study showed that cortisol, a hormone produced by the adrenal gland in response to stress, is found in high levels in chronic alcoholics, as well as those recovering from the condition.

24 Sep 2010

Breast cancer incidence drops, linked to decline in HRT use

A new Canadian study shows that a significant drop in breast cancer incidence among post-menopausal women from 2002 to 2004 coincided with a sharp drop in hormone replacement therapy (HRT) use during the same period. This is the first study to show the link between HRT use and breast cancer among Canadian women.

24 Sep 2010

Over one in three diabetics do not take insulin as prescribed

More than one in three diabetes patients skip doses or fail to take their insulin as prescribed, stating that they have done so on average three times in the last month, and 77 percent of physicians estimate that in reality this number could be as high as six doses, according to the Global Attitudes of Patients and Physicians in Insulin Therapy (GAPP™) survey, released today by Novo Nordisk.

23 Sep 2010

Semprae Laboratories markets Zestra to help make sex effortless for women

Last night's ABC NIGHTLINE segment questioned why culture and advertisers remain so reluctant to give women what they want. Meanwhile, for men, it's been common practice to discuss their sexual needs openly.

23 Sep 2010

New study signals hope for treatment of rare neurodegenerative disease

A new study led by St. Jude Children's Research Hospital scientists signals hope for treatment of a neurodegenerative disease and a new model for understanding the mechanism at work in other more common neurodegenerative disorders.

23 Sep 2010

Women face sexual function problems after breast cancer

A new study published in the Journal of Sexual Medicine looked at whether women were more likely to experience sexual problems after breast cancer. The results showed that 70% of women were facing sexual function problems approximately two years post diagnosis.

23 Sep 2010

Boehringer Ingelheim to present linagliptin Phase III data at 46th EASD

New Phase III data found that investigational linagliptin therapy resulted in significant reductions in blood sugar as measured by hemoglobin A1c (HbA1c) when compared to placebo, both when added to sulfonylurea (SU) in inadequately controlled type 2 diabetes (T2D) patients, and when administered as monotherapy in T2D patients for whom metformin is inappropriate.

22 Sep 2010

G-CSF compound may activate virus, increases risk of infection: Research

Research conducted at Oregon Health & Science University's Vaccine and Gene Therapy Institute may spur debate about the risks associated with administering a specific compound in some forms of bone-marrow transplantation. The research is published in the current edition of Cell Host and Microbe.

22 Sep 2010

Pancreas releases new NANETS guidelines on rare group of cancers

Neuroendocrine tumors (NETs) are a group of rare cancers that pose unique challenges in diagnosis and treatment. In a recent issue of Pancreas, official journal of the American Pancreatic Association, presents the newly developed consensus guidelines of the North American Neuroendocrine Tumor Society (NANETS).

22 Sep 2010

Dr. Shlomo Melmed awarded 9th Endocrine Regulation Prize of the Fondation Ipsen

The international jury under the presidency of Professor Iain Robinson (National Institute for Medical Research, London, UK) awarded today the 9th Endocrine Regulation Prize of the Fondation Ipsen (20.000€) to Dr. Shlomo Melmed (Cedars-Sinai Medical Center, Los Angeles, USA) during the annual congress of the ENEA (European NeuroEndocrine Association) in Liège (Belgium), for his translational approach to endocrinology. Shlomo Melmed is an internationally recognized endocrinologist and an authority on pituitary medicine.

22 Sep 2010