Hormone News and Research

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A hormone is a chemical released by one or more cells that affects cells in other parts of the organism. Only a small amount of hormone is required to alter cell metabolism. It is essentially a chemical messenger that transports a signal from one cell to another.

Discovery of inhibitory hormone may yield new treatments for cancer and other diseases

Nearly 10 years after the discovery that birds make a hormone that suppresses reproduction, University of California, Berkeley, neuroscientists have established that humans make it too, opening the door to development of a new class of contraceptive and possible treatments for cancer or other diseases.

23 Dec 2009

Poniard Pharmaceuticals sells common shares for $6.5 million

Poniard Pharmaceuticals today announced the sale of 3,489,728 of its common shares to Azimuth Opportunity Ltd. for net proceeds of approximately $6.5 million, or approximately $1.87 per share, under its existing committed equity financing facility with Azimuth.

23 Dec 2009

Researchers mix active drug and placebo to maximize drug benefits for efficient treatment

Researchers used the placebo effect to successfully treat psoriasis patients with one quarter to one half of their usual dose of a widely used steroid medication, according to an early study published online today in the journal Psychosomatic Medicine.

23 Dec 2009

Researchers recommend progesterone as viable treatment for traumatic brain injuries

Researchers at Emory University in Atlanta, GA, recommend that progesterone (PROG), a naturally occurring hormone found in both males and females that can protect damaged cells in the central and peripheral nervous systems, be considered a viable treatment option for traumatic brain injuries, according to a clinical perspective published in the January issue of the American Journal of Roentgenology.

23 Dec 2009

Hormone ghrelin influences the consumption of alcohol, study shows

A Faculty of 1000 evaluation examines how a stomach-produced hormone that influences the desire to eat and consume alcohol could be switched off to control drinking problems.

23 Dec 2009

Australian scientists show connections between brain and regulation of bone mass

The brain acts as a profound regulatory centre, controlling myriad processes throughout the body in ways we are only just beginning to understand. In new findings, Australian scientists have shown surprising connections between the brain and regulation of bone mass.

23 Dec 2009

Chordoma surgery through the nose

A remarkable brain surgery at Saint John’s Health Center has restored vision to a seriously ill young woman from Spain—and the entire operation was performed through her nose without an incision.

22 Dec 2009

Emisphere's oral salmon calcitonin product addresses persistent musculoskeletal pain

Emisphere Technologies, Inc. today announced a meta-analysis published in the December 2009 edition of Rheumatology Reports examining independent evidence of the analgesic action of the hormone calcitonin. This publication restates the potential of calcitonin in filling a significant unmet need for alternative treatments for persistent musculoskeletal pain.

22 Dec 2009

Researchers identify new method to tackle bacterial infections

Researchers from the University of Groningen have clarified the structure of an enzyme that disturbs the communication processes between bacteria. By doing so they have laid the foundations for a new method of tackling bacterial infections such as cystic fibrosis.

22 Dec 2009

Teva Pharmaceutical Industries, OncoGenex Pharmaceuticals announce collaboration in cancer therapy

Teva Pharmaceutical Industries Ltd. and OncoGenex Pharmaceuticals, Inc. announced today that they have entered into a global license and collaboration agreement to develop and commercialize OGX-011, as well as an agreement to purchase shares in OncoGenex. OGX-011 is a Phase III cancer therapy designed to inhibit cancer treatment resistance.

21 Dec 2009

GSK receives European CHMP positive opinion for Revolade

Ligand Pharmaceuticals Incorporated today announced that its partner GlaxoSmithKline has received a positive opinion for Revolade® (eltrombopag/Promacta®) from the European Medicines Agency’s Committee for Medicinal Products for Human Use (CHMP) for the oral treatment of thrombocytopenia (reduced platelet count) in adults with the blood disorder chronic immune (idiopathic) thrombocytopenic purpura (ITP).

18 Dec 2009

European CHMP announces positive opinion for Amgen's Prolia marketing authorization

Amgen Inc. today announced that the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) has announced a positive opinion for the marketing authorization of Prolia((TM)) (denosumab) for the treatment of osteoporosis in postmenopausal women at increased risk of fractures, and for the treatment of bone loss associated with hormone ablation in men with prostate cancer at increased risk of fractures.

18 Dec 2009

AEterna Zentaris terminates its agreement on cetrorelix with sanofi-aventis U.S.

AEterna Zentaris Inc. (the "Company"), a global biopharmaceutical company focused on oncology and endocrine therapy, today announced the termination of its agreement with sanofi-aventis U.S. ( SNY) dated March 5, 2009 for the development, commercialization and licensing of cetrorelix in benign prostatic hyperplasia (BPH) for the U.S. market, following the Company's announcement last week of the results for its European Phase 3 study for cetrorelix in BPH.

18 Dec 2009

Tufts researchers discover new neuron development in nulliparous mothers

Maternal behavior itself can trigger the development of new neurons in the maternal brain independent of whether the female was pregnant or has nursed, according to a study released by researchers at Tufts University's Cummings School of Veterinary Medicine.

18 Dec 2009

New technology sheds light on intracellular transport

Using new technology developed in his University of Oregon lab, chemist Andrew H. Marcus and his doctoral student Eric N. Senning have captured what they describe as well-orchestrated, actin-driven, mitochondrial movement within a single cell.

18 Dec 2009

Four commonly used chemotherapy drugs disrupt birth of new brain cells, shows study

Researchers have developed a novel animal model showing that four commonly used chemotherapy drugs disrupt the birth of new brain cells, and that the condition could be partially reversed with the growth factor IGF-1.

18 Dec 2009

Unigene Laboratories selects UGP281 lead peptide from obesity program for development

Unigene Laboratories, Inc. (http://www.unigene.com) announced today that it has selected a lead peptide compound, designated UGP281, from its obesity program for development.

18 Dec 2009

Ligand Pharmaceuticals, Neurogen revise merger agreement

Ligand Pharmaceuticals Incorporated and Neurogen Corporation announced today they have amended their merger agreement to increase the merger consideration payable

18 Dec 2009

Roche discloses results of two of eight taspoglutide T-emerge phase III studies in diabetes patients

Ipsen, an innovation-driven global specialty pharmaceutical group, today announced that its partner Roche has disclosed headline results of the fourth and fifth of eight T-emerge phase III studies in patients with diabetes for taspoglutide, the first once weekly glucagon-like peptide-1 (GLP-1) analogue based on a human sequence.

17 Dec 2009

People with higher Leptin levels have significantly reduced incidence of AD and dementia

This week’s issue of the Journal of the American Medical Association (Dec 16) features a report on a long-term, prospective study of elderly, dementia-free individuals led by researchers from Boston University School of Medicine and the Framingham Heart Study focusing on the association between the protein hormone Leptin and the risk of developing Alzheimer’s disease (AD).

17 Dec 2009

Hormone News and Research

Further Reading

Discovery of inhibitory hormone may yield new treatments for cancer and other diseases

Poniard Pharmaceuticals sells common shares for $6.5 million

Researchers mix active drug and placebo to maximize drug benefits for efficient treatment

Researchers recommend progesterone as viable treatment for traumatic brain injuries

Hormone ghrelin influences the consumption of alcohol, study shows

Australian scientists show connections between brain and regulation of bone mass

Chordoma surgery through the nose

Emisphere's oral salmon calcitonin product addresses persistent musculoskeletal pain

Researchers identify new method to tackle bacterial infections

Teva Pharmaceutical Industries, OncoGenex Pharmaceuticals announce collaboration in cancer therapy

GSK receives European CHMP positive opinion for Revolade

European CHMP announces positive opinion for Amgen's Prolia marketing authorization

AEterna Zentaris terminates its agreement on cetrorelix with sanofi-aventis U.S.

Tufts researchers discover new neuron development in nulliparous mothers

New technology sheds light on intracellular transport

Four commonly used chemotherapy drugs disrupt birth of new brain cells, shows study

Unigene Laboratories selects UGP281 lead peptide from obesity program for development

Ligand Pharmaceuticals, Neurogen revise merger agreement

Roche discloses results of two of eight taspoglutide T-emerge phase III studies in diabetes patients

People with higher Leptin levels have significantly reduced incidence of AD and dementia

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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