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SARS-CoV-2 test in 20 minutes with FISH

A collaboration from the University of Oxford and the University of Warwick has led to research into a novel method of viral detection through rapid fluorescence in situ hybridization (FISH) in order to effectively detect the SARS-CoV-2 virus within 20 minutes.

29 Jun 2021

SARS-CoV-2 can be neutralized by UV-A and UV-B

Since the end of the 1800s, Ultra-violet (UV) light has been widely documented for its germicidal properties. The UV-C light produced by low-pressure mercury tubes is widely used for disinfecting wastewater, closed environments, and biological products and is well-established, safe, and economical. UV light can have a germicidal effect on bacteria and viruses.

2 Jun 2021

A novel multiplexed diagnostic approach for COVID-19

Researchers developed a platform for detecting the virus directly from a patient's sample as well as the immune response through antibodies such as IgG and IgM.

31 May 2021

Oxytocin-vasopressin circuit has distinct dynamics throughout embryonic development

The work, carried out by Pilar Madrigal and Sandra Jurado, from the UMH-CSIC Neurosciences Institute in Alicante, a joint center of the Spanish National Research Council and Miguel Hernández University, has been published in Communications Biology, a Nature group´s journal.

22 May 2021

Monocytes promote viral control during SARS-COV-2 infection

In a paper recently uploaded to the preprint server bioRxiv by Vanderheiden et al. (May 4th, 2021) the contribution of monocytes in promoting protective immunity from SARS-CoV-2 is investigated in a murine model, suggesting that CCR2 plays the role of an inflammation modulator in early infection.

6 May 2021

SARS-CoV-2 does not directly infect the brain but can inflict neurological damage

SARS-CoV-2, the virus that causes COVID-19, likely does not directly infect the brain but can still inflict significant neurological damage, according to a new study from neuropathologists, neurologists, and neuroradiologists at Columbia University Vagelos College of Physicians and Surgeons.

17 Apr 2021

Researchers develop novel test that screens for SARS-CoV-2 variants of concern

A team of scientists from the United States has recently developed a single-tube duplex molecular assay for rapid detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants containing E484K and N501Y spike mutations.

30 Mar 2021

Researchers explain SARS-CoV-2's replication-transcription complex

The current pandemic of coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is still spreading rapidly throughout the world. A new preprint on the bioRxiv* server describes the structure of an important viral non-structural protein NSP12-16 and its role in SARS-CoV-2 infection.

22 Feb 2021

Visualization of SARS-CoV-2 RNA by fluorescence in situ hybridization probes

A team of scientists from France has recently designed fluorescence in situ hybridization probes (CoronaFISH) to visualize severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA in infected cells. A detailed description of the probe design, validation, and application is currently available on the bioRxiv preprint server.

7 Feb 2021

Gene panel test enables highly accurate diagnosis of liposarcomas

Researchers have leveraged the latest advances in RNA technology and machine learning methods to develop a gene panel test that allows for highly accurate diagnosis of the most common types of liposarcoma.

5 Feb 2021

Researchers develop ultra-small nanomedicines to target intractable cancers

Ultra-small nanomedicines of approximately 18 nm were fabricated by dynamic ion-pairing between Y-shaped block copolymers and nucleic acid drugs, such as siRNA and antisense drugs.

19 Jan 2021

FISH technique can be used to probe sperm DNA for chromosomal defects

Chemotherapy and radiation treatments are known to cause harsh side effects that patients can see or feel throughout their bodies.

19 Jan 2021

A paper-based sensor for detecting COVID-19

News-Medical talks to Dipanjan Pan about the development of a paper-based electrochemical sensor that can detect COVID-19 in less than five minutes.

5 Jan 2021

AOAC INTERNATIONAL issues Certificates of Validation for three test kits that detect SARS-CoV-2

AOAC INTERNATIONAL announced today that it has issued Certificates of Validation for three proprietary test kits that detect SARS-CoV-2, the causative agent of COVID-19 illness, on environmental surfaces.

18 Dec 2020

Research reveals two phases of infection in patients with severe COVID-19 pneumonia

What does SARS-CoV-2, the virus that causes COVID-19, do once it enters a person's airways, and how does infection in lung cells affect patients' immune responses?

16 Dec 2020

SARS-CoV-2 RNA can be reverse-transcribed to be part of chimeric viral-human genome

A new study reveals that the genome of SARS-CoV-2 is inserted into the human genome, accounting for the detection of viral RNAs.

16 Dec 2020

Rapid lateral flow immunoassay enables fluorescence detection of SARS-Cov-2 RNA

The COVID-19 pandemic has highlighted the need for rapid and accurate nucleic acid detection at the point of care. To meet this need, scientists from the Suzhou Institute of Biomedical Engineering and Technology have developed a novel amplification-free rapid SARS-CoV-2 nucleic acid detection platform based on hybrid capture fluorescence immunoassay (HC-FIA).

11 Dec 2020

Paper-based electrochemical sensor can enable rapid detection of SARS-CoV-2

As the COVID-19 pandemic continues to spread across the world, testing remains a key strategy for tracking and containing the virus.

7 Dec 2020

Accelerated biological aging not a risk factor for severe COVID-19, say researchers

A new study conducted by researchers at RWTH Aachen University in Germany has found no evidence to support the hypothesis that severe outcomes in cases of coronavirus disease 2019 (COVID-19) may be linked to accelerated biological aging.

17 Nov 2020

Study shows SARS-CoV-2 direct heart muscle cell infection, cell death, loss of contractility

In the study, published on the pre-print journal bioRxiv, the researchers revealed that SARS-CoV-2-infected EHTs manifested the typical characteristics of myocarditis or heart inflammation. These include the stimulation of immune cells, heart cell death, and decreased contractile force generation.

8 Nov 2020