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New fentanyl vaccine could prevent deadly opioid from entering the brain

A research team led by the University of Houston has developed a vaccine targeting the dangerous synthetic opioid fentanyl that could block its ability to enter the brain, thus eliminating the drug's "high."

14 Nov 2022

Manufacturers and suppliers influence how pharmacies buy, distribute opioid prescriptions, study finds

In today's post-pandemic world, strained global supply chains have emerged as a new norm. But in the case of prescription opioids, namely oxycodone and hydrocodone in the early 2000s, that supply chain flowed freely without any kinks.

7 Jun 2022

Study shows how a non-opioid approach successfully manages women's pain after C-section

For years, women recovering from cesarean section (C-section) deliveries have been given devices that let them, with a button, control the flow of opioid painkillers into their IV line. But as researchers and policymakers push to curb the use of opioids, clinicians are developing new strategies for treating pain after C-sections.

3 May 2022

At a Tennessee crossroads, two pharmacies, a monkey, and millions of pills

It was about 1 a.m. on April 19, 2016, when a burglary alarm sounded at Dale Hollow Pharmacy in Celina, a tiny town in the rolling, wooded hills near the Kentucky border.

29 Mar 2022

Research shows intergenerational effects of preconception opioids in male offspring rats

New research from scientists at Cummings School of Veterinary Medicine at Tufts University suggests opioid use before pregnancy-; even if not used during pregnancy itself-; could result in a higher likelihood that a mother's male offspring will develop type 2 diabetes and metabolic syndrome, conditions that increase the risk of heart disease and stroke.

28 Feb 2022

Persistent opioid use among 12% of patients after cardiac implantable electronic device procedures

About 12 percent of patients who receive implantable cardiac devices such as a pacemaker or defibrillator and fill an opioid prescription after surgery will consistently use the pain medication in the months afterward, raising the potential for addiction following these common procedures and identifying another pathway that could contribute to the national opioid crisis, according to a new study by researchers at the Perelman School of Medicine at the University of Pennsylvania.

26 Nov 2021

Researchers use residues in wastewater to study illicit drug consumption

At the start of the COVID-19 pandemic, stay-at-home orders and other restrictions drastically affected how people lived and worked, resulting in social isolation and economic instability. Now, researchers show that some people turned to a variety of drugs for relief. Using wastewater analysis, the team identified a spike in consumption of easily abused prescription opioids and anti-anxiety sedatives, while some illicit drug use plummeted, between March and June 2020.

23 Aug 2021

Hospital ‘trauma centers’ charge enormous fees to treat minor injuries and send people home

The care was ordinary. A hospital in Modesto, California, treated a 30-year-old man for shoulder and back pain after a car accident. He went home in less than three hours.

16 Jul 2021

Study finds higher risk of overdose in patients treated with opioids to reduce dental pain

When they go to the dentist to get a tooth pulled or another procedure, patients might not think that the prescription they receive to ease their pain could put them or their family at risk of an opioid overdose.

29 Apr 2021

Opioid prescription for new mothers associated with an increased risk of serious opioid-related events

A new study from Vanderbilt University Medical Center researchers finds that new mothers who receive opioids after uncomplicated vaginal births face an increased risk of serious opioid-related events regardless of the opioid dosage, a finding that could significantly impact care delivery.

26 Apr 2021

Policies designed to prevent opioid misuse may limit access to pain-relieving drugs

Policies designed to prevent the misuse of opioids may have the unintended side effect of limiting access to the pain-relieving drugs by terminally ill patients nearing the end of their life, new research led by the Oregon State University College of Pharmacy suggests.

20 Apr 2021

Rescheduling drugs can reduce use as well as the dangers, study finds

Many nations place drugs into various schedules or categories according to their risk of being abused and their medical value.

3 Feb 2021

Despite new CDC guidance, opioid prescription rates have not declined

Research from Saint Louis University finds that among patients at risk for opioid misuse, the odds of receiving a schedule II opioid for non-cancer pain were similar to those not at risk, despite new prescribing guidelines from the Centers for Disease Control (CDC).

2 Dec 2020

Back-pain patients taking opioid painkillers produce anti-opioid antibodies

University of Wisconsin-Madison scientists have discovered that a majority of back-pain patients they tested who were taking opioid painkillers produced anti-opioid antibodies.

17 Aug 2020

Study examines changes in prescription patterns during COVID-19 pandemic

A new study by investigators from Brigham and Women's Hospital examines changes in prescription patterns in the United States during the COVID-19 pandemic.

29 May 2020

Roughly half of opioid prescriptions by dentists exceed pain-management guidelines

A new study suggests that roughly half of the opioid prescriptions written by dentists in the United States exceed the three-day supply recommended by federal dental pain-management guidelines.

4 Feb 2020

Most youths do not get timely addiction treatment after opioid overdose

A study of more than 4 million Medicaid claims records during a recent seven-year period concludes that less than a third of the nearly 3,800 U.S. adolescents and young adults who experienced a nonfatal opioid overdose got timely (within 30 days) follow-up addiction treatment to curb or prevent future misuse and reduce the risk of a second overdose.

17 Jan 2020

Family doctors in rural America tackle crisis of addiction and pain

Dr. Angela Gatzke-Plamann didn’t fully grasp her community’s opioid crisis until one desperate patient called on a Friday afternoon in 2016.

10 Jan 2020

Proper disposal of leftover medication can help reduce antibiotic resistance

Proper disposal of leftover medication, particularly antibiotics and opioids, can help reduce antibiotic resistance, prevent children from being poisoned and stop the misuse of addiction-forming drugs.

31 Dec 2019

A veteran started vaping THC to cope with chronic pain. Then he got very sick.

As vaping has grown more popular in recent years, the trend has been fueled by the habit’s pleasurable allure: Compared with smoking cigarettes or pot, vaping is discreet and less smelly. Vaping fluids come in hundreds of flavors. There’s no tar or other byproducts of burning. And vape pens are high-tech, customizable and sleek.

20 Dec 2019