Hyperinsulinemia News and Research

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Hyperinsulinemia, or hyperinsulinaemia is a condition in which there are excess levels of circulating insulin in the blood. It commonly presents in people with diabetes mellitus type 2 or insulin resistance and is often associated with metabolic syndrome.

Study: Intake of carbohydrate-enriched foods after birth predisposes child to obesity later in life

Consumption of foods high in carbohydrates immediately after birth programs individuals for lifelong increased weight gain and obesity, a University at Buffalo animal study has found, even if caloric intake is restricted in adulthood for a period of time.

20 Mar 2013

Metformin therapy improves BMI and fasting glucose levels in obese children

Metformin therapy has a beneficial treatment effect over placebo in improving body mass index (BMI) and fasting glucose levels in obese children, according to a recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM). The study showed reduction in BMI was sustained for six months.

11 Dec 2012

Patients with Type 2 Diabetes may face increased risk of Barrett's Esophagus

Patients with Type 2 Diabetes may face an increased risk for Barrett's Esophagus (BE), regardless of other risk factors including smoking, alcohol consumption, obesity and gastroesophageal reflux disease (GERD), according to research unveiled today at the American College of Gastroenterology's (ACG) 77th Annual Scientific meeting in Las Vegas.

23 Oct 2012

ApoA-V as a contributor to dyslipidemia in obese children

Insulin may be an important regulator of serum apolipoprotein A-V levels in obese people and may contribute to the development of obesity-associated dyslipidemia, say Japanese researchers.

27 Sep 2012

Pioglitazone may raise bladder cancer risk

Study evidence supports a link between thiazolidinedione use, particularly pioglitazone, and bladder cancer in patients with Type 2 diabetes, Canadian researchers report.

9 Jul 2012

Pioglitazone may raise bladder cancer risk

Study evidence supports a link between thiazolidinedione use, particularly pioglitazone, and bladder cancer in patients with Type 2 diabetes, Canadian researchers report.

9 Jul 2012

Diabetes linked to increased blood cancer risk

Patients with Type 2 diabetes are at an increased risk for developing lymphoma, suggest findings from a US study.

11 Jun 2012

High blood sugar in combination with high insulin levels causes fatty deposits in the heart

The impaired substrate metabolism of diabetes patients is often expressed in an increase in fatty deposits in the cells of the heart muscle. Until now, the exact cause of this was unknown. Now, researchers at the MedUni Vienna in the Division of Endocrinology and Metabolism of MedUni Vienna in cooperation with the MR Centre of Excellence Vienna have shown that high blood sugar in combination with high levels of insulin - not an influx of fats - results in such deposits within a few hours.

16 Apr 2012

Hyperinsulinemia itself not a cause of atherosclerosis

A number of studies have shown that excess insulin circulating in the bloodstream is a major independent risk factor for cardiovascular disease. However, a new study from Joslin Diabetes Center finds that this condition, called hyperinsulinemia, is itself not a cause of atherosclerosis.

28 Mar 2012

Deadly link between higher BMI and colorectal cancer

The American College of Gastroenterology (ACG) and the Campaign to End Obesity (CEO) are joining forces to highlight the potentially deadly link between higher Body Mass Index (BMI) and colorectal cancer.

16 Mar 2012

Common link between Type 2 diabetes and autism

A review of the genetic and biochemical abnormalities associated with autism reveals a possible link between the widely diagnosed neurological disorder and Type 2 diabetes, another medical disorder on the rise in recent decades.

20 Oct 2011

Promising new strategy for treating human type 2 diabetes

In a mouse study, scientists at Mayo Clinic Florida have demonstrated the feasibility of a promising new strategy for treating human type 2 diabetes, which affects more than 200 million people worldwide.

10 Jun 2011

Promising new strategy for treating human type 2 diabetes

10 Jun 2011

Metformin therapy may protect PCOS women against endometrial cancer

Research led by Warwick Medical School at the University of Warwick has found that Metformin, a drug treatment used to treat diabetes and also in women with Polycystic vary syndrome, may potentially provide protection against endometrial cancer.

5 Apr 2011

Scientists reveal metabolic abnormalities underlying schizophrenia

Scientists in Finland have revealed metabolic abnormalities that are associated with schizophrenia. This may be an important step towards development of a clinical test of the disease.

5 Apr 2011

FDA accepts Merck's JANUMET extended-release formulation NDA for type 2 diabetes

Merck today announced that the New Drug Application (NDA) for the Company's investigational extended-release formulation of JANUMET for type 2 diabetes has been accepted for standard review by the U.S. Food and Drug Administration (FDA). The Company is also moving forward as planned with regulatory filings in countries outside the United States.

12 Jan 2011

Obesity is associated with worse outcomes in patients with ER-positive/HER2-negative disease

Obesity was associated with worse overall and disease-free survival in women with operable breast cancer treated with adjuvant chemotherapy, but for the first time, researchers observed this finding in only a specific subset of patients - those with estrogen receptor (ER)-positive/HER2-negative disease.

10 Dec 2010

Type 2 diabetes and insulin use associated with CRC risk in men, but not women

There is an association between type 2 diabetes mellitus and colorectal cancer (CRC) among men, but not women, according to a new study in Gastroenterology, the official journal of the American Gastroenterological Association (AGA) Institute.

19 Oct 2010

Researchers propose Nintendo Wii gaming to control gestational diabetes in women

Many women have trouble finding time to exercise in their busy lifestyles. That's especially true for pregnant women who live in northern climates such as Canada, where the weather can limit outdoor activity during winter months every year. But exercise is critical to managing gestational diabetes, a growing problem that occurs in 2 to 9 per cent of pregnancies.

14 Oct 2010

Metabolism imbalance increases asthma risk in children: Research

Even children of a healthy weight who have an imbalanced metabolism due to poor diet or exercise may be at increased risk of asthma, according to new research, which challenges the widespread assumption that obesity itself is a risk factor for asthma.

17 Sep 2010