Hypersensitivity is an exaggerated response by the immune system to a drug or other substance.
An ice cream cone on a hot July day can be a tasty way to beat the heat, but if you're one of the millions of people who have sensitive teeth, then that cold treat can be a real pain.
A tiny microRNA has been shown to play a beneficial role in protecting the brain from epileptic seizures in specially engineered transgenic mice. Scientists at the Hebrew University of Jerusalem say it could act as a protective mechanism to reduce the risk of epileptic seizures in humans.
It has long been assumed that chronic nerve pain is caused by hypersensitivity in the neurons that transmit pain.
Researchers at Lund University in Sweden have developed a method which determines not only whether a chemical or substance is allergenic, but also how strong its potential for causing hypersensitivity is.
Summer is approaching, and for many allergy sufferers this means it is time to start fearing bee stings. "Allergic reactions to insect venoms are potentially life-threatening, and constitute one of the most severe hypersensitivity reactions," explains PD Dr. Simon Blank, research group leader at the Center of Allergy & Environment, a joint undertaking by the Helmholtz Zentrum München and the TUM.
Researchers at National Jewish Health have identified a trigger for autoimmune diseases such as lupus, Crohn's disease and multiple sclerosis.
Mallinckrodt plc, a specialty pharmaceutical company, announced new results from two company-sponsored studies: one study on use of H.P. Acthar® Gel (repository corticotropin injection) in patients with infantile spasms (IS) and a second study on the economic burden of moderate-to-severe multiple sclerosis (MS) relapse.
The U.S. Food and Drug Administration today approved Rydapt (midostaurin) for the treatment of adult patients with newly diagnosed acute myeloid leukemia who have a specific genetic mutation called FLT3, in combination with chemotherapy.
The U.S. Food and Drug Administration today approved Brineura (cerliponase alfa) as a treatment for a specific form of Batten disease. Brineura is the first FDA-approved treatment to slow loss of walking ability in symptomatic pediatric patients 3 years of age and older with late infantile neuronal ceroid lipofuscinosis type 2 (CLN2), also known as tripeptidyl peptidase-1 (TPP1) deficiency.
Why are women at higher risk of complications after total hip or knee replacement surgery? An increased rate of hypersensitivity to the metals contained in joint implants might be a contributing factor, suggests a study in the April 19 issue of The Journal of Bone & Joint Surgery. The journal is published by Wolters Kluwer.
Amgen and UCB today announced results from the fourth year of a Phase 2 study showing the efficacy and safety of a second course of treatment with EVENITY™* (romosozumab), an investigational agent for postmenopausal women with osteoporosis.
Using PET scans of the brain, University of Michigan researchers showed that dopamine falls and fluctuates at different times during a migraine headache.
New method for the diagnosis of autism was found by researchers at Mie University. Autism is a neurodevelopmental disorder, characterized by impairments in social interaction, communication and sensory abnormalities, such as sensitivity to sounds (auditory hypersensitivity). Despite intense research, the causes are still unknown.
Improved hygiene has largely eliminated infectious diseases from everyday life. There is, however, a downside to this progress: the number of allergies is growing steadily.
New computer models from North Carolina State University show how a variant of a common protein involved in human immune response binds to the antiviral drug abacavir, causing a severe life-threatening reaction known as the abacavir hypersensitivity syndrome
A new study in rats suggests that nicotinamide riboside (NR), a form of vitamin B3, may be useful for treating or preventing nerve pain (neuropathy) caused by chemotherapy drugs.
A tiny snail may offer an alternative to opioids for pain relief. Scientists at the University of Utah have found a compound that blocks pain by targeting a pathway not associated with opioids.
Pain is a signal of actual or potential damage to the body, so it is natural to think of it as a localized sensation: knee pain in the knee, back pain in the back and so on.
The Ten Steps for a Healthy Pregnancy, aims to offer mums-to-be essential advice to adopt good habits for healthy growth and development for both mum and baby.
Adults on the autism spectrum see their interests as possible fields of study and career paths, as well as ways to mitigate anxiety, finds a study by NYU's Steinhardt School of Culture, Education, and Human Development.