Hypersensitivity is an exaggerated response by the immune system to a drug or other substance.
A research team at the University of California, Riverside, has found exposure to sound -- not sound reduction -- during early development of mice engineered to have Fragile X Syndrome, or FXS, restores molecular, cellular, and functional properties in the auditory cortex, the area of the brain that processes sounds.
A new study has revealed the underlying mechanism of development of antibiotic resistance among Pseudomonas aeruginosa (P. aeruginosa). Pseudomonas is known to cause severe and often life threatening infections in humans. These infections become further difficult to treat because of the development of resistance against commonly used antibiotics.
An article entitled "Human Peripheral Blood Eosinophils Express High Levels of the Purinergic Receptor P2X4" written by an international immunology research group was recently published in the scientific journal Frontiers in Immunology.
People with autism often experience hypersensitivity to noise and other sensory input. MIT neuroscientists have now identified two brain circuits that help tune out distracting sensory information, and they have found a way to reverse noise hypersensitivity in mice by boosting the activity of those circuits.
Native to South America, imported fire ants have now spread to parts of North America and elsewhere around the world. These invasive pests have painful stings that, in some cases, can cause serious medical problems, such as hypersensitivity reactions, infections and even kidney failure.
A protein called RGS4 (Regulator of G protein signaling 4) plays a prominent role in the maintenance of long-term pain states and may serve as a promising new target for the treatment of chronic pain conditions, according to research conducted at the Icahn School of Medicine at Mount Sinai and published in print October 16, in The Journal of Neuroscience.
Peripherally inserted central catheters (PICCs) that use a magnetized tip to guide insertion were associated with serious allergic reactions in patients, according to a study published today in Infection Control & Hospital Epidemiology, the journal for the Society for Healthcare Epidemiology of America. Severe adverse reactions occurred in patients within minutes of PICC insertion.
Cincinnati Children's Hospital Medical Center has received a 5-year, $7.57 million grant renewal from the National Institutes of Health to continue leading a consortium of organizations from around the country that will conduct clinical research into eosinophilic gastrointestinal disorders.
Dry skin, pain, and itching... Atopic dermatitis affects the everyday lives of nearly 20% of children, and up to 5% of adults. The condition can have a significant impact on the quality of life of these patients.
Nintedanib, a medication approved for the treatment of idiopathic pulmonary fibrosis, slows the decline in lung function among patients with a broad range of scarring lung diseases.
Researchers from North Carolina State University have found that inflammation increases neuronal activity, gene expression and sensory nerve (neurite) outgrowth in neurons involved in thermal - but not physical- sensations in mice.
International physiologists and researchers studying the kidney, high blood pressure and related medical conditions will convene next week at the American Physiological Society (APS) Aldosterone and ENaC in Health and Disease: The Kidney and Beyond Conference in Estes Park, Colo.
Researchers in South Korea have found that patients with family and personal history of allergic reactions to contrast media are at risk for future reactions, according to a large study published in the journal Radiology.
A recent large German study has shown that a new combination therapy for breast cancer treatment leads to a lowered risk of the disease coming back. A commentary on this landmark clinical trial has been published in the latest issue of the Journal of Clinical Oncology by the researchers Masey Ross and Charles Geyer Jr. from the VCU Massey Cancer Center. The commentary was titled, “Nab-Paclitaxel: A New Standard of Care in Neoadjuvant Therapy of High-Risk Early Breast Cancer?”
Researchers from University of Virginia School of Medicine have uncovered the mystery behind development of allergic reactions to red meat such as beef in some individuals. Recently there has been a body of research on allergies to meat developing in individuals due to tick bites.
Researchers from Japan's Osaka University have made an important leap in our understanding of how chronic pain conditions develop.
The U.S. Food and Drug Administration today approved Xenleta (lefamulin) to treat adults with community-acquired bacterial pneumonia.
The U.S. Food and Drug Administration today approved Pretomanid Tablets in combination with bedaquiline and linezolid for the treatment of a specific type of highly treatment-resistant tuberculosis of the lungs.
The inability to tolerate light touch is a telltale feature of autism and one of the disorder's many perplexing symptoms. It has defied treatment, and its precise origins have remained somewhat of a mystery.
The U.S. Food and Drug Administration today approved Baqsimi nasal powder, the first glucagon therapy approved for the emergency treatment of severe hypoglycemia that can be administered without an injection.