Hypersensitivity is an exaggerated response by the immune system to a drug or other substance.
Many people with autism spectrum disorders are highly sensitive to light, noise, and other sensory input. A new study in mice reveals a neural circuit that appears to underlie this hypersensitivity, offering a possible strategy for developing new treatments.
A recent study published in the journal Cephalalgia, the official journal of the International Headache Society, builds on the sensorial characteristics of migraine patients.
In 2019, the emergence of mysterious lung disease in the United States has sparked global health attention. Now named as the e-cigarette, or vaping, product use–associated lung injury (EVALI), the disease causes lung damage, which is a serious and sometimes fatal complication of vaping.
A new study raises the possibility of modulating asthma symptoms via the bacteria that commonly live in the upper airway. The work, which was published on December 16, 2019, in the journal Nature Communications, shows that in children who have mild to moderate asthma, the microbiome of the upper airway could determine how severe the symptoms are.
A recent study published in the journal Cephalalgia, the official journal of the International Headache Society, highlights an overlooked relationship between migraine and exercise.
The American Academy of Dermatology has honored board-certified dermatologists Steven Daveluy, MD, FAAD, and Benjamin Workman, MD, FAAD, as Patient Care Heroes for their teamwork with oncologists to diagnose a rare condition affecting just one in a million patients, known as drug-induced hypersensitivity syndrome.
A new study published in the journal Scientific Reports says that for the first time a vaccine has been created against bovine tuberculosis that can be given without affecting the ability to diagnose tuberculosis later using the PPD skin test.
A new study published in the November 19, 2019 issue of JAMA shows that a newly developed small molecule drug called ubrogepant may successfully fight migraine at doses of 25 and 50 mg, with pain relief at 2 hours with both doses, while the most troublesome symptom of migraine was held off at 2 hours post-dose with the 50 mg dose. This may help millions of migraine patients to achieve pain relief and function better.
A soft pillow and a warm duvet are all you need to have a soothing and relaxing sleep, especially during the frigid season. However, a man from the United Kingdom nearly died because of a mysterious illness related to a duvet. It was later found out by doctors that the culprit for his lung disease is his newly-bought feather duvet.
A new study published in the Journal of the American College of Cardiology shows that e-cigarettes have toxic effects on neutrophils function, making them a threat to human health by increasing the likelihood of infection with Gram-negative bacteria.
A small study published in the journal JCI Insight on November 14, 2019, suggests that antibody treatment could help people with severe allergy to peanuts eat a small amount of peanut-containing food just two weeks later, without any ill effects. This seems to show that this is a safe, fast and effective treatment for food allergy.
The Centre for Disease Control and Prevention (CDC) has warned earlier last month about the possible risk of lung inflammation from the exposure to the fluid in e-cigarettes. Now a case of a 16-year-old boy was reported with life threatening lung inflammation leading to respiratory failure.
A research team at the University of California, Riverside, has found exposure to sound -- not sound reduction -- during early development of mice engineered to have Fragile X Syndrome, or FXS, restores molecular, cellular, and functional properties in the auditory cortex, the area of the brain that processes sounds.
A new study has revealed the underlying mechanism of development of antibiotic resistance among Pseudomonas aeruginosa (P. aeruginosa). Pseudomonas is known to cause severe and often life threatening infections in humans. These infections become further difficult to treat because of the development of resistance against commonly used antibiotics.
An article entitled "Human Peripheral Blood Eosinophils Express High Levels of the Purinergic Receptor P2X4" written by an international immunology research group was recently published in the scientific journal Frontiers in Immunology.
People with autism often experience hypersensitivity to noise and other sensory input. MIT neuroscientists have now identified two brain circuits that help tune out distracting sensory information, and they have found a way to reverse noise hypersensitivity in mice by boosting the activity of those circuits.
Native to South America, imported fire ants have now spread to parts of North America and elsewhere around the world. These invasive pests have painful stings that, in some cases, can cause serious medical problems, such as hypersensitivity reactions, infections and even kidney failure.
A protein called RGS4 (Regulator of G protein signaling 4) plays a prominent role in the maintenance of long-term pain states and may serve as a promising new target for the treatment of chronic pain conditions, according to research conducted at the Icahn School of Medicine at Mount Sinai and published in print October 16, in The Journal of Neuroscience.
Peripherally inserted central catheters (PICCs) that use a magnetized tip to guide insertion were associated with serious allergic reactions in patients, according to a study published today in Infection Control & Hospital Epidemiology, the journal for the Society for Healthcare Epidemiology of America. Severe adverse reactions occurred in patients within minutes of PICC insertion.
Cincinnati Children's Hospital Medical Center has received a 5-year, $7.57 million grant renewal from the National Institutes of Health to continue leading a consortium of organizations from around the country that will conduct clinical research into eosinophilic gastrointestinal disorders.