Hypertrophic Cardiomyopathy News and Research

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Hypertrophic cardiomyopathy is a condition that affects the heart’s ability to pump blood effectively due to the thickening (hypertrophy) of the heart muscle which becomes stiff as a result.

New approach can help treat hypertrophic cardiomyopathy with precision medicine

Hypertrophic cardiomyopathy (HCM) is a cardiovascular disease characterized by thickening of the left ventricle, otherwise known as the main squeezing chamber of the heart. HCM is best known for causing sudden death in athletes but can occur in persons of any age, often without symptoms.

26 Feb 2021

Updated guideline on hypertrophic cardiomyopathy encourages shared decision-making

The American Heart Association and the American College of Cardiology today released an updated guideline for managing patients with hypertrophic cardiomyopathy (HCM).

22 Nov 2020

Study shows favorable impact of medication on cardiac structure and function

For the first time, medication has impacted heart muscle thickness and function for patients with the most common inherited heart condition, rather than simply addressing their symptoms.

17 Nov 2020

WSU research sheds new light on a drug that may be used to treat hypertrophic cardiomyopathy

Research at Washington State University sheds new light on one molecule that may be used to treat a heart condition that can lead to stroke, heart attack and other forms of heart disease.

27 Oct 2020

Cats’ immune system can deal with SARS-CoV-2, shows study

On 8 May 2020, the Institute of Agrifood Research and Technology (IRTA) reported the case of the first cat infected with SARS-CoV-2 in Spain. It was a 4-year-old cat called Negrito, who lived with a family affected by COVID-19, with one case of death.

22 Sep 2020

Study: Mavacamten improves heart function in patients with hypertrophic cardiomyopathy

Mavacamten improves heart function and symptoms in patients with obstructive hypertrophic cardiomyopathy, according to results of the EXPLORER-HCM trial presented in a Hot Line session today at ESC Congress 2020.

31 Aug 2020

New study assesses cardiac problems in elite female athletes

The first-ever cardiac study of elite female basketball players in the United States shows how their hearts adapt to intense physical training.

25 Jun 2020

New mathematical model to study the behavior of the human heart

Having now reached its third year, Project "iHEART" of Politecnico di Milano, winner of an ERC Advanced Grant of euro 2,350,000, has set itself the ambitious goal of creating a complete mathematical model to study the behavior of the human heart and of its pathologies, a sort of "virtual microscope."

20 May 2020

Reductive stress is intolerable, can induce heart failure

Many heart diseases are linked to oxidative stress, an overabundance of reactive oxygen species. The body reacts to reduce oxidative stress -- where the redox teeter-totter has gone too far up -- through production of endogenous antioxidants that reduce the reactive oxygen species.

14 May 2020

ECG screening more effective at detecting cardiac conditions in college athletes

Over the past 30 years, colleges and universities have increasingly screened athletes for health conditions that may pose undue risk to sports participation. Sudden cardiac death is the leading cause of death among college athletes, so a primary function of these screenings is to reveal unknown heart conditions.

4 May 2020

Study shows why people with certain heart diseases may be more susceptible to COVID-19

People with certain heart diseases may be more susceptible to worse outcomes with COVID-19, but the reason why has remained unknown.

28 Apr 2020

Study identifies a protein and signaling pathway that may contribute to sudden cardiac death

By studying the sick hearts removed from four patients undergoing heart transplants, researchers have identified a protein and a signaling pathway that may contribute to sudden death in an inherited form of heart disease.

3 Mar 2020

AI-based approach may allow EKGs to be used for detecting hypertrophic cardiomyopathy

An approach based on artificial intelligence may allow EKGs to be used to screen for hypertrophic cardiomyopathy in the future.

18 Feb 2020

New book focuses on heart failure in pediatric patients

The field of heart failure in pediatric populations has recently initiated more registries and clinical trials. This age group has special concerns and particularities regarding their clinical picture and management. Therefore, multiple disciplines have been involved in the management of heart failure in this age group.

11 Feb 2020

Study traces the molecular roots of hypertrophic cardiomyopathy

The heart's ability to beat normally over a lifetime is predicated on the synchronized work of proteins embedded in the cells of the heart muscle.

27 Jan 2020

New program receives national recognition for treating hypertrophic cardiomyopathy

When Kayla Green was first diagnosed with hypertrophic cardiomyopathy, she felt vindicated.

4 Dec 2019

Researchers reveal initial results from a study of hypertrophic cardiomyopathy

Researchers have revealed the initial results from the world's largest comprehensive study of hypertrophic cardiomyopathy, an abnormal thickening of the heart that often goes undiagnosed and can prove deadly. The condition can present at any age, and it is the most common cause of sudden cardiac death in young athletes.

7 Nov 2019

Study finds no overall improvement in heart transplant waitlist after policy change

In March 2016, the Organ Procurement and Transplantation Network revised its criteria for prioritizing children awaiting heart transplantation in the U.S. with the intention of reducing the number of deaths on the waitlist, but a new study suggests unintended consequences.

23 Sep 2019

Research opens possibility of developing single-dose gene therapy for inherited arrhythmias

Researchers at Boston Children's Hospital report creating the first human tissue model of an inherited heart arrhythmia, replicating two patients' abnormal heart rhythms in a dish, and then suppressing the arrhythmia with gene therapy in a mouse model.

17 Jul 2019

Being overweight around age 18 linked with higher risk of cardiomyopathy in adulthood

A large study of Swedish men found that those who were even mildly overweight around age 18 were more likely develop cardiomyopathy in adulthood -- an uncommon heart muscle condition that can cause heart failure, according to new research in the American Heart Association's journal Circulation.

27 May 2019