Hypospadias News and Research

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$Is there an association between residential proximity to fracking sites and birth defects?$

Is there an association between residential proximity to fracking sites and birth defects?

Study explores the incidence of birth defects in children born to mothers residing within 10 km of fracking sites.

19 Apr 2023

Epigenetic alternations associated with common genital malformation in male babies

An alarming increase in the occurrence of the most common genital malformation in male babies, hypospadias, is likely due to environmental factors, such as toxicant exposure, which alter epigenetic programming in a forming penis.

18 Jan 2023

Macrolide, penicillin antibiotics in pregnancy could affect children’s health

A new study published in the journal BMJ in February 2020 reports that macrolide or penicillin antibiotic consumption in pregnancy could be linked to several adverse health outcomes in children. These include major malformations, cerebral palsy, attention deficit hyperactivity disorder, and autism spectrum disorder.

20 Feb 2020

Boys born small at higher risk of infertility

A new study published in the journal Human Reproduction on December 13, 2019, shows that baby boys who don’t grow as well as expected in the womb may grow up to be infertile as adults. The study showed a 55% or 85% higher risk of infertility among this group of men compared to those born with appropriate weights.

15 Dec 2019

Study finds no link between infant deaths and exposure to waste incinerators

Researchers have found no link between exposure to emissions from municipal waste incinerators and infant deaths or reduced foetal growth.

21 Jun 2019

Study seeks to better understand the genetic causes for hypospadias

Daniel Casella, M.D., a urologist at Children's National, was honored with an AUA Mid-Atlantic Section William D. Steers, M.D. Award, which provides two years of dedicated research funding that he will use to better understand the genetic causes for hypospadias.

22 Apr 2019

Testosterone is not the only hormone needed for penis development

A new study has revealed that in addition to testosterone, the masculinization process involves a hormone called androsterone, which originates in other tissues.

15 Feb 2019

Scientists aim to find genetic causes of developmental abnormalities in the vagina and uterus

A percentage of females are born with a missing or underdeveloped vagina and uterus, and scientists are working to analyze the genes of hundreds of them to get a better idea about causes, improve genetic counseling and ideally treatment.

22 Jan 2019

Women who drink more water experience fewer bladder infections, study finds

In the controlled trial, women who drank an additional 1.5 liters of water daily experienced 48 percent fewer repeat bladder infections than those who drank their usual volume of fluids, said senior author Dr. Yair Lotan, Professor of Urology and with the Simmons Cancer Center at UT Southwestern.

1 Oct 2018

New report proposes strategy to evaluate low-dose toxicity of endocrine disruptors

A new report by the National Academies of Sciences, Engineering, and Medicine proposes a strategy that the U.S. Environmental Protection Agency should use to evaluate the evidence of adverse human health effects from low doses of exposure to chemicals that can disrupt the endocrine system.

18 Jul 2017

Medical City Frisco pediatric urologists break down barriers regarding penile birth defects

One of the most common birth defects in newborn baby boys is never discussed, never seen in the media and rarely mentioned in medical educational material.

23 Jun 2017

Scientists identify key gene in 22q11.2 that contributes to genitourinary birth defects

The 22q11.2 region of human chromosome 22 is a hotspot for a variety of birth defects. Scientists learned about this region because it is deleted in about 1 in 4,000 births, causing the loss or duplication of up to 40 genes.

25 May 2017

Study reveals promising new strategy to treat birth defect in boys

A study published in Scientific Reports describes a potential new strategy that may be utilized to correct hypospadias, a birth defect which occurs when boys are born with a urinary opening on the underside of the penis, found in up to one in every 200 boys.

21 Oct 2016

Finding may lead to better understanding of male genital birth defects

University of Florida Health researchers have identified genes that are disrupted by abnormal hormone signaling at crucial points during development, a finding that may lead to a better understanding of how the most common male genital birth defects arise in humans.

24 Nov 2015

Prenatal exposure to phthalate DiNP associated with shorter AGD in Swedish boys: Study

The first study to examine prenatal exposure to the phthalate DiNP finds it is associated with a shorter anogenital distance (AGD) in Swedish boys at the age of 21 months. These findings raise concern since animal research has linked DiNP exposure to a shorter AGD, and studies on humans have related shorter AGD to male genital birth defects as well as impaired reproductive function in adult males, and the levels of DiNP metabolites in humans are increasing globally.

30 Oct 2014

CHLA physician discusses urological issues in children

Children's Hospital Los Angeles physician-scientist Roger E. De Filippo, MD, an associate professor of urology and director of Pediatric Urology Stem Cell Research at the Keck School of Medicine of the University of Southern California discusses how science, technology and parental care can lead to improved pediatric urological health.

21 Oct 2014

Hypospadias News and Research

Is there an association between residential proximity to fracking sites and birth defects?

Epigenetic alternations associated with common genital malformation in male babies

Macrolide, penicillin antibiotics in pregnancy could affect children’s health

Boys born small at higher risk of infertility

Study finds no link between infant deaths and exposure to waste incinerators

Study seeks to better understand the genetic causes for hypospadias

Testosterone is not the only hormone needed for penis development

Scientists aim to find genetic causes of developmental abnormalities in the vagina and uterus

Women who drink more water experience fewer bladder infections, study finds

New report proposes strategy to evaluate low-dose toxicity of endocrine disruptors

Medical City Frisco pediatric urologists break down barriers regarding penile birth defects

Scientists identify key gene in 22q11.2 that contributes to genitourinary birth defects

Study reveals promising new strategy to treat birth defect in boys

Finding may lead to better understanding of male genital birth defects

Prenatal exposure to phthalate DiNP associated with shorter AGD in Swedish boys: Study

CHLA physician discusses urological issues in children

Scientists define genetic cause for two types of birth defects in newborn boys

Common birth defect in male infants weakly linked to commercial pesticides

Researchers discover link between epilepsy drug and risk of having baby with birth defects

Risk for childhood cancer moderately increased among adolescents with major birth defects

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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