Hypospadias News and Research

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Perthes’ disease link to congenital disorders revealed

Researchers have linked Perthes' disease with several congenital conditions, pointing to intra-uterine factors behind the development of the disease.

14 Dec 2012

Tubularized incised plate procedure effective for boys with hypospadias

A pediatric urologist at UT Southwestern Medical Center who pioneered a surgical technique for repairing a common birth defect in boys reports the procedure is singularly effective in correcting the problem with few complications.

15 Jun 2011

Pediatric urology research papers published in two Elsevier journals

The first World Congress of Pediatric Urology was held in San Francisco in May 2010, bringing together the largest and most successful international congregation of pediatric urologists ever assembled. As part of a collaborative effort, The Journal of Urology and the Journal of Pediatric Urology have together published the landmark papers presented at this meeting.

2 May 2011

Study finds association between DGKK gene and hypospadias

Hypospadias is a common congenital malformation of the male external genitalia, affecting 1 in 375 boys. In hypospadias patients, the urethral opening is not located at the tip of the penis, but somewhere halfway, at the base of the penis, or even in the scrotum.

29 Nov 2010

Study sheds light on molecular mechanisms of genital and urinary tract abnormalities

Scientists have learned how a gene widely known for precisely positioning and sculpting various organs also controls the speed of cell division, a finding that could be useful for understanding the explosive growth of cancer cells or why increasing numbers of children are being born with genital and urinary tract malformations.

2 Jun 2010

Relatives of men with cryptorchidism or hypospadias not at risk of developing testicular germ cell cancer

Boys with the sexual birth defects known as hypospadias and cryptorchidism are at risk for developing testicular germ cell cancer, but their relatives are not, according to a new study published online December 21 in the Journal of the National Cancer Institute.

22 Dec 2009

Exposure to stress hormones and chemicals while in the womb can affect male fertility

Exposure to a combination of excess stress hormones and chemicals while in the womb could affect a man's fertility in later life, a study suggests.

22 Oct 2009

Hairspray linked to common genital birth defect in baby boys

British scientists from Imperial College London say women who are exposed to hairspray in the workplace during pregnancy have more than double the risk of having a son with the genital birth defect hypospadias.

24 Nov 2008

Significant link between hairspray and genital birth defect hypospadias

Women who are exposed to hairspray in the workplace during pregnancy have more than double the risk of having a son with the genital birth defect hypospadias, according to a new study published today in the journal Environmental Health Perspectives.

21 Nov 2008

Healthy male reproductive organs depend on early hormone activity

A discovery by Medical Research Council scientists looking at the development of male foetuses could help explain the origin of common genital disorders that can cause reproductive problems or increase risk of low sperm counts and possibly testicular cancer later in life.

20 Mar 2008

Cryptorchidism and hypospadias

Cryptorchidism, the absence in the scrotum of one or both testes (usually because of the failure of the testis to descend), and hypospadias, the abnormal positioning of the opening of the urethra, are common birth defects of the male genitalia and are risk factors for the adult-onset disorders of low sperm count and testicular cancer.

14 Mar 2008

Mix of endocrine disrupters a dangerous cocktail

Endocrine-disrupting chemicals, which are harmless individually in small doses, can together be a dangerous cocktail.

20 Feb 2008

Maternal obesity and birth defects

Mothers of babies born with some structural birth defectsincluding missing limbs, malformed hearts and underdeveloped spinal cordsappear more likely to be obese prior to becoming pregnant than mothers whose children are born without such defects, according to a report in the August issue of Archives of Pediatrics & Adolescent Medicine, one of the JAMA/Archives journals.

7 Aug 2007