Hypoxia News and Research

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Hypoxia is a condition in which there is a decrease in the oxygen supply to a tissue. In cancer treatment, the level of hypoxia in a tumor may help predict the response of the tumor to the treatment.

Study offers new insight into the underlying brain mechanisms of sleep apnea-induced hypertension

Nearly 40 million adults in the U.S. have sleep apnea, and more than 30 million of them use a continuous positive airway pressure (CPAP) machine while sleeping.

23 Jul 2024

Mitochondrially-targeted antioxidants could reduce SARS-CoV-2 effects across multiple organs

Building upon groundbreaking research demonstrating how the SARS-CoV-2 virus disrupts mitochondrial function in multiple organs, researchers from Children's Hospital of Philadelphia (CHOP) demonstrated that mitochondrially-targeted antioxidants could reduce the effects of the virus while avoiding viral gene mutation resistance, a strategy that may be useful for treating other viruses.

15 Jul 2024

How does SARS-CoV-2 cause lymphopenia when T cells barely express ACE-2 receptors?

Researchers reveal both direct and indirect mechanisms of SARS-CoV-2-induced lymphopenia, highlighting the role of CD147 and alternative viral entry routes into T cells.

8 Jul 2024

Key differences in RNA editing found between postmortem and living brain

Researchers examined the adenosine-to-inosine (A-to-I) nucleoside editing of postmortem and live prefrontal cortical tissues.

3 Jul 2024

Fibrinogen-like protein 1 plays dual role in liver regeneration and hepatocellular carcinoma recurrence

Hepatocellular carcinoma (HCC), a leading cause of cancer-related mortality globally, exhibits a dismal five-year survival rate of only 18%.

2 Jul 2024

Engineered E. coli optimizes targeted tumor cell killing and improves biosafety

Live bacteria can be applied in cancer therapy given their ability to deplete nutrients and induce cell death in tumors.

1 Jul 2024

Researchers shine light on the nuanced functions and intricate regulatory methods of RNA editing

Researchers from the Icahn School of Medicine at Mount Sinai have shed valuable light on the nuanced functions and intricate regulatory methods of RNA editing, a critical mechanism underlying brain development and disease.

28 Jun 2024

KU researchers uncover role of Src gene in nervous system development

Many people are familiar with oncogenes -; genes long known to be involved in cancers in humans, such as the gene "Src."

24 Jun 2024

Mathematical modeling reveals hemoglobin's role in silent hypoxemia of COVID-19

Since 2020, the COVID-19 pandemic has presented significant challenges to global public health, infecting millions and claiming numerous lives.

18 Jun 2024

Mitophagy fuels cancer stem cell growth and survival

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 11, entitled, "Mitophagy and cancer: role of BNIP3/BNIP3L as energetic drivers of stemness features, ATP production, proliferation, and cell migration."

18 Jun 2024

Low-cost quality improvement program lowers mortality in El Salvador's pediatric ICU

Pediatric intensive care units (PICUs) in low and middle-income countries see elevated mortality rates, often 10 times higher than those in high-income countries.

12 Jun 2024

Flight risk: Alcohol and cabin hypoxia disrupts sleep quality and impacts heart health

How alcohol consumption and exposure to hypobaric hypoxia interact to affect heart rate, blood oxygen saturation (SpO2), and sleep.

6 Jun 2024

Common anti-inflammatory drug could combat deadly gut fungus, study finds

A team of UC Davis Health researchers discovered that a common anti-inflammatory drug, mesalamine, can replace the work of good bacteria in fighting the nasty fungus Candida albicans in the gut.

4 Jun 2024

Alcohol plus cabin pressure at higher altitude may threaten sleeping plane passengers' heart health

The combination of alcohol plus cabin pressure at cruising altitude may threaten sleeping plane passengers' heart health, particularly on long haul flights, suggests the first study of its kind, published online in the respiratory journal Thorax.

4 Jun 2024

Heavy menstrual bleeding raises heart disease risk in young women

Study found that heavy menstrual bleeding (HMB) is linked to increased cardiovascular disease (CVD) risk in young women, even without irregular menstruation.

28 May 2024

Study finds rise in hospitalizations for ischemic priapism

Researchers analyzed nationwide data from Germany to evaluate trends and outcomes in hospitalized cases of high- and low-flow priapism, finding increased hospitalizations for ischemic priapism and reduced cases linked to sickle cell disease.

26 May 2024

Study uncovers key biological pathways driving psoriasis inflammation

A certain biological pathway, a set of linked reactions in the body, drives the inflammation seen in the skin disease psoriasis, a new study finds.

20 May 2024

Research explores the effects of nuclear magnetic resonance on internal clock of cells

A research collaboration between the Faculty of Biochemistry and Molecular Medicine at the University of Oulu, Finland, the University of Innsbruck, Austria, and Florida Tech, USA, explored the effects of nuclear magnetic resonance on the internal clock of cells at different times of day and under oxygen deprivation.

13 May 2024

Identification of pathogenicity-associated milRNAs in Fusarium oxysporum f. sp. cubense

Fusarium oxysporum f. sp. cubense (Foc) is a typical soil-borne fungus that causes Fusarium wilt by infecting the roots and blocking the vascular tissues of host banana, and threatens the global banana production.

10 May 2024

Targeted nanoparticle delivery of FZD4 decreases lung tumor growth and metastasis

A recent breakthrough study from the lab of Tanya Kalin, MD, PhD, professor of Child Health and Internal Medicine at the University of Arizona College of Medicine – Phoenix, has shown potential to improve therapeutic outcomes for patients suffering from lung cancers.

16 Apr 2024