Hypoxia News and Research

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Hypoxia is a condition in which there is a decrease in the oxygen supply to a tissue. In cancer treatment, the level of hypoxia in a tumor may help predict the response of the tumor to the treatment.

Disrupted glucose transport in oligodendrocytes linked to myelin thinning and aging in new research

This study uncovers how oligodendroglial lipid metabolism supports myelin homeostasis and axonal function under metabolic stress, crucial for neurodegeneration.

11 Sep 2024

A study confirms that smoking significantly increases the risk of stroke

Findings indicate smoking elevates stroke risk, particularly in older males with comorbidities, underscoring the need for targeted prevention strategies.

28 Aug 2024

GLP-1 therapy boosts visceral fat metabolism, driving weight loss

Researchers discuss the role of enhanced visceral adipose tissue metabolism in mediating weight loss by glucagon-like peptide-1 drugs.

26 Aug 2024

Maternal gut bacteria linked to changes in fetal brain metabolism

The impact of Bifidobacterium breve's presence in the maternal gut during pregnancy on fetal brain metabolism.

23 Aug 2024

New implantable device could revolutionize opioid overdose response

A swine model to demonstrate the potential of an implantable system for opioid safety (iSOS).

19 Aug 2024

Understanding iron overload in β-thalassemia: Mechanisms, diagnosis, and treatments

β-Thalassemia is a genetic disorder characterized by reduced or absent synthesis of the beta chains of hemoglobin, leading to ineffective erythropoiesis and severe anemia.

29 Jul 2024

Study offers new insight into the underlying brain mechanisms of sleep apnea-induced hypertension

Nearly 40 million adults in the U.S. have sleep apnea, and more than 30 million of them use a continuous positive airway pressure (CPAP) machine while sleeping.

23 Jul 2024

Mitochondrially-targeted antioxidants could reduce SARS-CoV-2 effects across multiple organs

Building upon groundbreaking research demonstrating how the SARS-CoV-2 virus disrupts mitochondrial function in multiple organs, researchers from Children's Hospital of Philadelphia (CHOP) demonstrated that mitochondrially-targeted antioxidants could reduce the effects of the virus while avoiding viral gene mutation resistance, a strategy that may be useful for treating other viruses.

15 Jul 2024

How does SARS-CoV-2 cause lymphopenia when T cells barely express ACE-2 receptors?

Researchers reveal both direct and indirect mechanisms of SARS-CoV-2-induced lymphopenia, highlighting the role of CD147 and alternative viral entry routes into T cells.

8 Jul 2024

Key differences in RNA editing found between postmortem and living brain

Researchers examined the adenosine-to-inosine (A-to-I) nucleoside editing of postmortem and live prefrontal cortical tissues.

3 Jul 2024

Fibrinogen-like protein 1 plays dual role in liver regeneration and hepatocellular carcinoma recurrence

Hepatocellular carcinoma (HCC), a leading cause of cancer-related mortality globally, exhibits a dismal five-year survival rate of only 18%.

2 Jul 2024

Engineered E. coli optimizes targeted tumor cell killing and improves biosafety

Live bacteria can be applied in cancer therapy given their ability to deplete nutrients and induce cell death in tumors.

1 Jul 2024

Researchers shine light on the nuanced functions and intricate regulatory methods of RNA editing

Researchers from the Icahn School of Medicine at Mount Sinai have shed valuable light on the nuanced functions and intricate regulatory methods of RNA editing, a critical mechanism underlying brain development and disease.

28 Jun 2024

KU researchers uncover role of Src gene in nervous system development

Many people are familiar with oncogenes -; genes long known to be involved in cancers in humans, such as the gene "Src."

24 Jun 2024

Mathematical modeling reveals hemoglobin's role in silent hypoxemia of COVID-19

Since 2020, the COVID-19 pandemic has presented significant challenges to global public health, infecting millions and claiming numerous lives.

18 Jun 2024

Mitophagy fuels cancer stem cell growth and survival

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 11, entitled, "Mitophagy and cancer: role of BNIP3/BNIP3L as energetic drivers of stemness features, ATP production, proliferation, and cell migration."

18 Jun 2024

Hypoxia News and Research

Further Reading

Disrupted glucose transport in oligodendrocytes linked to myelin thinning and aging in new research

A study confirms that smoking significantly increases the risk of stroke

GLP-1 therapy boosts visceral fat metabolism, driving weight loss

Maternal gut bacteria linked to changes in fetal brain metabolism

New implantable device could revolutionize opioid overdose response

Understanding iron overload in β-thalassemia: Mechanisms, diagnosis, and treatments

Study offers new insight into the underlying brain mechanisms of sleep apnea-induced hypertension

Mitochondrially-targeted antioxidants could reduce SARS-CoV-2 effects across multiple organs

How does SARS-CoV-2 cause lymphopenia when T cells barely express ACE-2 receptors?

Key differences in RNA editing found between postmortem and living brain

Fibrinogen-like protein 1 plays dual role in liver regeneration and hepatocellular carcinoma recurrence

Engineered E. coli optimizes targeted tumor cell killing and improves biosafety

Researchers shine light on the nuanced functions and intricate regulatory methods of RNA editing

KU researchers uncover role of Src gene in nervous system development

Mathematical modeling reveals hemoglobin's role in silent hypoxemia of COVID-19

Mitophagy fuels cancer stem cell growth and survival

Low-cost quality improvement program lowers mortality in El Salvador's pediatric ICU

Flight risk: Alcohol and cabin hypoxia disrupts sleep quality and impacts heart health

Common anti-inflammatory drug could combat deadly gut fungus, study finds

Alcohol plus cabin pressure at higher altitude may threaten sleeping plane passengers' heart health

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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