Hypoxia News and Research

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Hypoxia is a condition in which there is a decrease in the oxygen supply to a tissue. In cancer treatment, the level of hypoxia in a tumor may help predict the response of the tumor to the treatment.

Philips collaborates with Mayo Clinic to climb Mount Kilimanjaro on research expedition

Royal Philips today announced it will be among the leading organizations collaborating with the Mayo Clinic to climb Mount Kilimanjaro on a research expedition to understand how the body reacts to the rigors of high altitude and how those learnings can be applied to improving human health.

10 Aug 2016

Scientists link malfunctioning molecular pathways to specific heart abnormalities in SCA

Patients with sickle cell anemia (SCA) develop heart complications and nearly a quarter die a sudden death. Now, researchers have linked malfunctioning molecular pathways to specific heart anomalies in SCA that result from progressive fibrosis and result in sudden death.

9 Aug 2016

Wistar scientists discover novel mechanism that helps tumors adapt to hypoxia

One of the many reasons tumors are so difficult to treat is that they are able to adapt whenever they are exposed to unfavorable conditions.

9 Aug 2016

Sleep-disordered breathing promotes progression of pediatric NAFLD to NASH

Studies have shown that obstructive sleep apnea and low nighttime oxygen, which result in oxidative stress, are associated with the progression of non-alcoholic fatty liver disease (NAFLD) in adults.

5 Aug 2016

Scientists measure eye pressure of sleeping patients to find link between OSAS and glaucoma

Scientists at Hokkaido University have successfully measured the eye pressure of sleeping patients with obstructive sleep apnea syndrome for the first time, finding an unexpected correlation with glaucoma.

22 Jul 2016

Breakthrough research shows cellular stress could be key to variety of birth defects

For the first time, scientists believe they've discovered a cause of multiple types of birth defects triggered by environmental stresses.

20 Jul 2016

Identifying new pathway of EZH2 gene may lead to targeted therapies for aggressive breast cancer

Scientists from A*STAR's Genome Institute of Singapore and the Cancer Science Institute of Singapore at the National University of Singapore came together to understand how EZH2, a cancer-promoting gene which is known to be involved in many types of cancers, is activated in breast cancer and lymphomas.

19 Jul 2016

Physicians may need to allow sufficient time before predicting outcomes in comatose cardiac arrest patients

Physicians may be drawing conclusions too soon about survival outcomes of patients who suffered a cardiac arrest outside the hospital.

4 Jul 2016

Mice study shows influence of dad's obesity on daughter’s body weight and breast cancer risk

Obese male mice and normal weight female mice produce female pups that are overweight at birth through childhood, and have delayed development of their breast tissue as well as increased rates of breast cancer.

24 Jun 2016

Breast cancer cells use new signaling pathway to cope with lack of oxygen levels inside tumors

Researchers have identified a new signaling pathway that helps cancer cells cope with the lack of oxygen found inside tumors. These are the results of a study published in Nature Cell Biology on June 20, and led by researchers at NYU Langone Medical Center and its Laura and Isaac Perlmutter Cancer Center, Princess Margaret Cancer Center, the University of Toronto, Harvard Medical School and Oxford University.

21 Jun 2016

New research helps better understand role of TIP60 in allowing tumors to survive in low-oxygen environments

In summer 2011, University of Colorado Cancer Center investigators Joaquín Espinosa, PhD, and Matthew Galbraith, PhD, taught a summer symposium on gene expression at Cold Spring Harbor Laboratory in Long Island, New York.

17 Jun 2016

New technique may help replace brain cells, restore memory

Although brains—even adult brains—are far more malleable than we used to think, they are eventually subject to age-related illnesses, like dementia, and loss of cognitive function.

15 Jun 2016

Scientists find new way to slow growth of triple negative breast cancer

CANCER RESEARCH UK scientists have found a new way to slow the growth of the most aggressive type of breast cancer, according to research published in the journal Oncogene today (Monday).

14 Jun 2016

Researchers investigate causes of renal failure using mathematical model

No one can deny that open-heart surgery, where the heart is exposed and the blood is made to bypass it, is one of the most invasive of all medical procedures. Nearly a third of all patients undergoing heart surgery experience kidney failure, yet little is known about why kidney injury occurs or how to prevent it.

9 Jun 2016

Yale researchers identify mechanisms responsible for human egg aging

Yale School of Medicine researchers have identified the molecular pathways involved in the aging of human eggs. This research could eventually lead to treatments to correct age-related damage and improve fertility in women age 40 and older.

8 Jun 2016

Accumulation of fat droplets makes cancer cells more aggressive

It has been established that not all cancer cells are equally aggressive - most can be neutralised with radiation and chemotherapy. Researchers at Lund University in Sweden have now discovered that some cancer cells can accumulate fat droplets, which appear to make them more aggressive and increase their ability to spread.

3 Jun 2016

Cardioprotective effect proposed for metformin

A large retrospective analysis suggests that metformin could be cardioprotective in insulin-dependent patients with Type 2 diabetes.

21 May 2016

MERS individuals develop severe critical illness, higher mortality than non-MERS SARI patients

Patients with Middle East Respiratory Syndrome (MERS) develop more severe critical illness and have higher mortality than patients with non-MERS severe acute respiratory infection (SARI), according to investigators involved with the largest study of critically ill patients with MERS.

19 May 2016

New set of practice guidelines from WMS may help in treatment, prevention of drowning

Drowning is a global threat to human health. Each year, more than 372,000 people die as a result of drowning, with many of those deaths being preventable by simple water safety measures. In order to arm professionals with the most up-to-date clinical protocols, the Wilderness Medical Society has issued a new set of practice guidelines for both the treatment and prevention of drowning, published in the society's official journal, Wilderness and Environmental Medicine.

10 May 2016

Researchers examine critical role of hypoxia in induction, amplification of FOP lesions

The cellular response to the lack of oxygen fans the flames of flare-ups in a rare bone disorder. In fibrodysplasia ossificans progressiva (FOP), a mutation triggers bone growth in muscles, which limits motion, breathing, and swallowing, among a host of progressive symptoms.

3 May 2016