Ibuprofen News and Research

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Ibuprofen is a drug used to treat fever, swelling, pain, and redness by preventing the body from making a substance that causes inflammation. It is a type of nonsteroidal anti-inflammatory drug (NSAID). Ibuprofen is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic effects. Ibuprofen inhibits the activity of cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes. This leads to decreased prostaglandin synthesis, by prostaglandin synthase, the main physiologic effect of ibuprofen. Ibuprofen also causes a decrease in the formation of thromboxane A2 synthesis, by thromboxane synthase, thereby inhibiting platelet aggregation.

Ibuprofen improves cognitive function in rats induced with chronic liver failure

Cognitive impairment is one of the neurological effects in patients with hepatic encephalopathy (abnormal brain function due to severe liver disease).

2 Aug 2007

The future of Alzheimer's disease research

Imagine the day when a routine visit to the family doctor includes a simple blood test to predict the risk for developing Alzheimer's disease (AD).

26 Jul 2007

Paracetamol for pain relief after surgical removal of lower wisdom teeth

The commonly used and inexpensive analgesic acetaminophen (Tylenol or paracetamol) is an effective pain reliever after surgical removal of lower wisdom teeth, according to a new systematic review of 21 studies.

18 Jul 2007

New way to increase stem cells in blood

Researchers at Children's Hospital Boston report finding a new way to increase stem cells in blood, suggesting a possible treatment to help patients who undergo chemotherapy or bone marrow transplant for leukemia and other cancers recover their immune function more quickly.

23 Jun 2007

All pain medications may raise risk of heart attack or stroke

Not long ago, choosing a pain reliever meant finding one that eased your pain without being too hard on the stomach.

1 Jun 2007

JRRD releases issue on pain

Effects of depression and pain severity on satisfaction in medical outpatients: Analysis of the Medical Outcomes Study, pg. 143 Patient satisfaction is a critical measure of healthcare quality.

1 Jun 2007

Researchers look at benefits of aspirin for colon cancer prevention

A colon cancer researcher at the Ireland Cancer Center of University Hospitals Case Medical Center (UHCMC) has laid out the roadmap for how medical science should employ aspirin and new aspirin-like drugs for use in preventing colon cancer in certain high-risk individuals.

24 May 2007

COX inhibitors may weaken protective qualities of estrogen therapy

Researchers from the University of Pennsylvania School of Medicine found in a database study of women heart patients that COX inhibitors such as traditional nonsteroidal anti-inflammatory drugs (NSAIDs) may undermine any purported protection against heart disease in participants taking estrogen therapy.

24 May 2007

Facts about rheumatoid arthritis and aging

For the better part of three decades, Sherrie Kossoudji has endeavored each day to manage the inflammation, chronic pain, tight joints and other types of physical strife caused by rheumatoid arthritis.

8 May 2007

Doctors say too many Brits addicted to OTC drugs

Doctors in Britain are warning about the dangers of becoming addicted to over-the-counter (OTC) medicines; they say more research is needed on how many misuse OTC drugs.

7 May 2007

Naproxen and celecoxib do not prevent Alzheimer's disease

Over-the-counter pain medication naproxen and prescription pain reliever celecoxib do not prevent Alzheimer's disease, according to a study published April 25, 2007, in the online edition of Neurology, the scientific journal of the American Academy of Neurology.

26 Apr 2007

Researchers study the possible use of carboranes

When protein plaque builds up in the blood, it can result in serious diseases such as heart disease and Alzheimer's.

25 Apr 2007

Time for FDA to set the record straight on common painkillers

The U.S. Food and Drug Administration (FDA) has caused an unnecessary scare about some pain relievers by adding a warning to drugs that are safe, says Curt Furberg, M.D., Ph.D., from Wake Forest University School of Medicine.

25 Apr 2007

Migraine sufferers keep their marbles later in life

Researchers in the United States are suggesting that women who have suffered a lifetime of migraine experience have less cognitive decline than women without migraine.

24 Apr 2007

Mixing certain allergy medications with other medicines can have hazardous effects on your health

Allergy season is here, and over-the-counter allergy medications are flying off the shelves.

24 Apr 2007

Migraines may help women protect their memory

Women with a lifetime history of migraine showed less of a performance decline over time on cognitive tests than women who didn't have migraines.

24 Apr 2007

Aspirin, cancer and lung inflamation

Two new studies by researchers at the at the Mayo Clinic have found that taking aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs) on a regular basis may offer some protection against cancer.

18 Apr 2007

Associations between smoking, caffeine and NSAID use and Parkinson's disease

Individuals with Parkinson's disease are less likely to smoke or consume high doses of caffeine than their family members who do not have the disease, according to a report in the April issue of Archives of Neurology, one of the JAMA/Archives journals.

10 Apr 2007

Smoking and drinking lots of coffee may protect against Parkinson's disease

In what must be a rare example of smoking supposedly providing some benefit, researchers in the U.S. say in families with a history of Parkinson's disease, those who smoke cigarettes and drink lots of coffee appear to reduce their risk of developing the disease.

9 Apr 2007