Ibuprofen News and Research

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Ibuprofen is a drug used to treat fever, swelling, pain, and redness by preventing the body from making a substance that causes inflammation. It is a type of nonsteroidal anti-inflammatory drug (NSAID). Ibuprofen is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic effects. Ibuprofen inhibits the activity of cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes. This leads to decreased prostaglandin synthesis, by prostaglandin synthase, the main physiologic effect of ibuprofen. Ibuprofen also causes a decrease in the formation of thromboxane A2 synthesis, by thromboxane synthase, thereby inhibiting platelet aggregation.

NSAID use linked to higher risk of blood clots in women of reproductive age, association stronger in women on high-risk hormonal contraception

A new paper published in The BMJ explores the effect of these drugs used concomitantly on the risk of venous thromboembolism (VTE).

8 Sep 2023

Women using NSAIDs alongside hormonal contraception may be at increased risk of blood clots

Women who use non-steroidal anti-inflammatory painkillers alongside hormonal contraception appear to be at a small increased risk of blood clots known as venous thromboembolism (VTE), finds a large Danish study published by The BMJ today.

7 Sep 2023

New guideline supports use of acetaminophen and NSAIDs for pediatric dental pain

Acetaminophen or non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen are recommended as first-line treatments for managing short-term dental pain in children under age 12, according to a new clinical practice guideline developed by the American Dental Association Science & Research Institute (ADASRI), the University of Pittsburgh School of Dental Medicine and the Center for Integrative Global Oral Health at the University of Pennsylvania School of Dental Medicine.

25 Aug 2023

Study explores the effectiveness of caffeine consumption for headaches: trigger or remedy?

Caffeine has a dual role in headaches as it can induces or remediate them.

20 Jul 2023

Researchers convert β-Pinene into renewable feedstock for sustainable paracetamol and ibuprofen

Researchers have developed scalable processes to convert β-pinene into 4-IPEC, a feedstock for synthesizing sustainable versions of paracetamol and ibuprofen.

19 Jul 2023

Seven risk factors for early onset colorectal cancer in males identified

Colorectal cancer incidence and deaths are declining for individuals age 50 and older, but are increasing for those under 50.

27 Jun 2023

Study finds lack of high certainty evidence on the efficacy and safety of analgesics for low back pain

Despite nearly 60 years of research, there is still a lack of high certainty evidence on the effectiveness and safety of commonly used painkillers (analgesics) for short bouts of low back pain, finds an analysis of the evidence published by The BMJ.

23 Mar 2023

Routine monitoring of wastewater could provide early warning for the next epidemic

Researchers analyzing wastewater say that routine monitoring at sewage treatment works could provide a powerful early warning system for the next flu or norovirus epidemic, alerting hospitals to prepare and providing public health agencies with vital health information.

22 Mar 2023

Exploring airway-to-brain sensory pathways in influenza-induced illness

In a recent study published in the Nature journal, researchers assessed the role of the airway-to-brain sensory pathways in influenza-induced illness.

13 Mar 2023

Study illuminates how the brain senses infection

A new study led by researchers at Harvard Medical School illuminates how the brain becomes aware that there is an infection in the body.

8 Mar 2023

New approach to pain management can reduce opioid use after urethroplasty

For men undergoing surgery to repair scarring in the urethra (urethroplasty), a new approach to pain management can reduce the need for strong opioid drugs without compromising pain control, reports a study in Urology Practice, an Official Journal of the American Urological Association.

21 Feb 2023

Acute tubulointerstitial nephritis and uveitis in children post-COVID-19

A new study reported a novel form of post-acute coronavirus disease 2019 (COVID-19) syndrome in children.

31 Jan 2023

Fluid on the lungs associated with open water swimming

Fluid on the lungs, or pulmonary edema as it's formally known, is a relatively little known hazard associated with open water swimming, warn doctors in the journal BMJ Case Reports after treating a woman with the condition.

10 Jan 2023

Are patients with a history of MIS-C at increased risk of adverse reactions from COVID-19 vaccination?

Researchers investigated the reactogenicity of the COVID-19 vaccine in pediatric patients with MIS-C.

5 Jan 2023

Machine learning analysis suggests that there are four sub-phenotypes of long COVID

Researchers identified PASC [post-acute sequelae of coronavirus disease 2019 (COVID-19)] sub-phenotypes depending on conditions diagnosed within 1 to 3 months of acute infection by SARS-CoV-2.

6 Dec 2022

Anti-inflammatory pain relievers may worsen inflammation in osteoarthritis

Taking anti-inflammatory pain relievers like ibuprofen and naproxen for osteoarthritis may worsen inflammation in the knee joint over time, according to a new study being presented next week at the annual meeting of the Radiological Society of North America.

21 Nov 2022

RSV and kids: What you need to know

An overview on the prevalence, symptoms, and management of RSV in children.

2 Nov 2022

Short-term NSAID use linked with first-time heart failure hospitalization in patients with type 2 diabetes

Short-term use of non-steroidal anti-inflammatory drugs (NSAIDs) is associated with a first-time hospitalization for heart failure in patients with type 2 diabetes, according to research presented at ESC Congress 2022.

23 Aug 2022

Low-cost intervention could easily be used to right-size opioid prescribing after surgery

A small tweak to hospitals' prescribing systems might make a big difference in reducing risk from leftover opioid pain medication, while still making sure surgery patients get relief from their post-operation pain, a new study suggests.

30 Jun 2022

What you need to know about monkeypox

The World Health Organization said June 25 that monkeypox wasn't yet a public health emergency of international concern. More than 4,500 cases have been reported worldwide, with more than 300 in the U.S. And with public health officials unable to follow all chains of transmission, they're likely undercounting cases.

29 Jun 2022