Immune Response News and Research

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Understanding of metal-free enzymes used by bacteria could lead to new effective antibiotics

Some bacterial pathogens, including those that cause strep throat and pneumonia, are able to create the components necessary to replicate their DNA without the usually required metal ions.

19 Oct 2018

LJI and UC San Diego awarded $ 4.5 million as part of NCI's Cancer Moonshot initiative

Researchers at La Jolla Institute for Immunology and UC San Diego have been awarded $ 4.5 million as part of the National Cancer Institute's Cancer Moonshot initiative.

19 Oct 2018

New DNA vaccine strategy protects mice against lethal challenge by multiple H3N2 viruses

Researchers developed a novel DNA influenza vaccine based on four micro-consensus antigenic regions selected to represent the diversity of seasonal H3N2 viruses across decades.

18 Oct 2018

New findings reveal potential cellular players in tumor microenvironment

New findings presented today by CytoReason reveals possible new cellular players in the tumor microenvironment that could impact the treatment process for the most in-need patients - those who have already failed to respond to ipilimumab (anti-CTLA4) immunotherapy.

16 Oct 2018

Rice University chemist wins big award to study small surfaces

It's one thing to start a chemical reaction and get a result, but it's quite another thing to watch it in progress. Rice University chemist Matt Jones wants to see it happen.

16 Oct 2018

Researchers develop fibrin-targeting immunotherapy to protect against neurodegeneration

Normally, the blood protein fibrin does not enter the brain. But in several neurological disorders, the blood-brain barrier--which keeps large molecules in the blood from entering the brain--becomes abnormally permeable, allowing fibrin to leak into the brain and trigger inflammation.

16 Oct 2018

Potential 'early warning markers' for sepsis discovered

A multi-site research collaboration supported by a Technology Strategy Board Grant has shown that immune response signatures could be used as an early warning test for the serious condition sepsis in patients attending emergency departments with suspected infection.

15 Oct 2018

First-of-its-kind study to test a personalized vaccine in cancer patient

Tamara Strauss has been living with high-grade, stage IV pancreatic neuroendocrine cancer for more than three years. Current treatments, although effective for her, are highly toxic.

15 Oct 2018

Researchers to study the use of CRISPR on human liver on-a-chip platform

Two Arizona State University professors are among the first recipients of Somatic Cell Genome Editing grants from the National Institutes of Health Common Fund. The $2,600,000, five-year grant will fund the first study of the genome editing technology CRISPR to be used on a "human liver on-a-chip" platform.

15 Oct 2018

Sugar, a “sweet” tool to understand brain injuries

Australian researchers have developed ground-breaking new technology which could prove crucial in treating brain injuries and have multiple other applications, including testing the success of cancer therapies.

14 Oct 2018

Researchers develop two-pronged approach for targeting Ebola virus

In a new study researchers have developed a two-pronged approach for targeting Ebola virus infection using linked nucleic acid (LNA) antisense oligonucleotides (ASOs)designed to interfere both genes essential for translation of Ebola virus genes and to block production of an intracellular human protein needed for the virus to enter cells.

12 Oct 2018

A new vaccine shows promise in protecting people from rabies, Lassa fever

A novel vaccine designed to protect people from both Lassa fever and rabies showed promise in preclinical testing, according to new research published in Nature Communications.

12 Oct 2018

Active role of water in a promising biomarker against cancer

The UPV/EHU's Department of Physical Chemistry and the Biofísika Institute have conducted a multidisciplinary study of the Tn antigen that appears in 90% of cancers.

12 Oct 2018

Computational model helps predict immune response in patients undergoing heart surgery

A research team led by Peter Sloot, professor of Complex Adaptive Systems at the UvA, has managed to pinpoint the mechanisms behind the immune response triggered in patients undergoing open heart surgery.

11 Oct 2018

New vaccine shows effective protection in animal models of Lassa fever

Lassa fever belongs to the same class of hemorrhagic fevers as Ebola. Like Ebola, it has been a major health threat in Western Africa, infecting 100,000-300,000 people and killing 5,000 per year.

11 Oct 2018

Researchers unravel fresh clues as to how kidney stones form

Kidney stones--solid, pebble-like grit that forms when too much of certain minerals like calcium are in the urine--can strike men, women, and increasingly, children, and the presence and pain of stones afflicts more than 12 percent of the world's population.

11 Oct 2018

Study sheds light on lupus's autoimmune origins in precursor cells

In the autoimmune disease systemic lupus erythematosus or SLE, the immune system produces antibodies against parts of the body itself. How cells that produce those antibodies escape the normal "checks and balances" has been unclear, but recent research from Emory University School of Medicine sheds light on a missing link.

11 Oct 2018

Healthy gut microbiome shown to be important for recovery after heart attack

The community of microorganisms that live in the human gut has been shown to confer all kinds of health benefits. Now, an international team of researchers has shown in mice that a healthy gut microbiome is important for recovery after a heart attack.

10 Oct 2018

Researchers devise a simple way to boost efficacy of malarial TBVs

For decades, scientists have been trying to develop a vaccine that prevents mosquitoes from spreading malaria among humans.

9 Oct 2018

Arcus Biosciences announces presentation of final results from Phase 1 study of AB928 at ESMO 2018

Arcus Biosciences, Inc., a clinical-stage biopharmaceutical company focused on creating innovative cancer immunotherapies, today announced that it will present final results from the Phase 1 study of AB928, its dual adenosine receptor antagonist, in healthy volunteers during a poster display session at the European Society of Medical Oncology 2018 Congress, being held October 19-23, 2018, in Munich, Germany.

8 Oct 2018