Immune Response News and Research

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Scientists develop potential new therapy for targeting skin cancer metastases in the brain

Investigators from Brigham and Women's Hospital (BWH) and the Harvard Stem Cell Institute have a potential solution for how to kill tumor cells that have metastasized to the brain.

10 Jul 2017

UMMS scientists design human protein-based tumor-targeting MRI contrast agent

A team led by Gang Han, PhD, has designed a human protein-based, tumor-targeting Magnetic Resonance Imaging contrast that can be easily cleared by the body.

10 Jul 2017

JAX researchers explore how dendritic cells promote adaptive immunity to virus

A research team led by Jackson Laboratory Professor Karolina Palucka, M.D., Ph.D., in collaboration with a research team at Institut Curie in France led by Dr. Nicolas Manel, have addressed a long-standing puzzle of immunology: How do dendritic cells (DCs) do their job of promoting adaptive immunity to a virus while avoiding getting infected themselves?

7 Jul 2017

Novel vaccine approach appears to protect fetus from CMV infection, animal study shows

Long before the Zika virus became a global fear, cytomegalovirus, or CMV, was commonly infecting developing fetuses and causing many of the same brain and developmental impairments.

6 Jul 2017

Scientists develop novel DNA-based strategy to protect against broad array of influenza viruses

A novel, synthetic, DNA-based strategy to provide protection against a broad array of influenza viruses has been developed in preclinical models by scientists at The Wistar Institute, MedImmune (the global biologics research and development arm of AstraZeneca) and Inovio Pharmaceuticals, Inc.

6 Jul 2017

Study: Personalized neoantigen vaccine stimulates strong anti-tumor response in melanoma patients

A personal cancer treatment vaccine that targets distinctive "neoantigens" on tumor cells has been shown to stimulate a potent, safe, and highly specific immune anti-tumor response in melanoma patients, report scientists from Dana-Farber Cancer Institute and the Broad Institute of MIT and Harvard.

5 Jul 2017

Discovery could impact understanding, treatment of autoimmune and inflammatory diseases

Scientists from the Research Institute of the McGill University Health Centre may have cracked the code to understanding the function of special cells called regulatory T Cells.

5 Jul 2017

Combination treatment could be more effective against common infection

The common and highly resistant Pseudomonas aeruginosa bacterium is a fatal threat to weakened and ill patients.

4 Jul 2017

New portable device can quickly find markers of sepsis from single drop of blood

A new portable device can quickly find markers of deadly, unpredictable sepsis infection from a single drop of blood.

3 Jul 2017

NEI-funded research aims to prevent or reverse progression of cataracts

Research funded by the National Eye Institute aims to reverse progression of cataracts- the most common cause of blindness worldwide- or to prevent them from forming altogether.

30 Jun 2017

Scientists find new clues to how RSV causes disease

By age 2, most children have been infected with respiratory syncytial virus (RSV), which usually causes only mild cold symptoms. But people with weakened immune systems, such as infants and the elderly, can face serious complications, including pneumonia and -- in some cases -- death.

30 Jun 2017

Proteins impeding antitumor immunity could be 'Achilles heel' of some cancers

By comparing variations in protein expression in tumor samples from a single melanoma patient, researchers from the Johns Hopkins Bloomberg~Kimmel Institute and the Memorial Sloan-Kettering Cancer Center say their findings have the potential to reveal some of the mechanisms underlying response or resistance to immunotherapy drugs.

28 Jun 2017

Study: Postponing lymph node biopsy after melanoma diagnosis does not affect long-term outcomes

Postponing lymph node biopsy more than 30 days after melanoma diagnosis doesn't adversely impact long-term clinical outcomes, according to new study findings published online as an "article in press" on the Journal of the American College of Surgeons website ahead of print publication.

28 Jun 2017

Study develops dissolvable microneedle patches for administering influenza vaccine

Study findings published online in The Lancet on June 27, 2017 have found that an experimental patch of dissolving microneedles can produce robust immune responses for influenza. The microneedle patches can be administered safely and can be a substitute for the needle-and-syringe vaccination. With further advancements, they could remove the uneasiness in using an injection and inconvenience of visiting a flu clinic, as well as offering cost benefits.

28 Jun 2017

New cranberry derivative could help patients dependent on tube feeding

Synesis, a University of Wisconsin-Madison spinoff developing a patented formula for liquid nutrition, is advancing a plant-based additive designed to reduce or eliminate severe side effects of tube feeding.

28 Jun 2017

Bandage-strip sized microneedle patches can transform flu vaccination method

A National Institutes of Health-funded study led by a team at the Georgia Institute of Technology and Emory University has shown that an influenza vaccine can produce robust immune responses and be administered safely with an experimental patch of dissolving microneedles.

28 Jun 2017

Study finds link between upper GI infections and protein implicated in Parkinson’s disease

Acute and chronic infections in a person's upper gastrointestinal tract appear to be linked to Parkinson's disease, say scientists at Georgetown University Medical Center and their collaborators at the National Institutes of Health and other institutions.

28 Jun 2017

Four-food elimination diet can resolve symptoms of eosinophilic esophagitis in children

Children with eosinophilic esophagitis (EoE) – a chronic inflammatory disease that injures the esophagus – who temporarily eliminated cow's milk, wheat, egg and soy from their diet for eight weeks had their symptoms and esophageal swelling resolve, according to a study published in Clinical Gastroenterology and Hepatology.

27 Jun 2017

Researchers study Lassa fever patient's immune response and viral persistence

When an American nurse working in West Africa became ill with Lassa fever and was evacuated to the U.S. for treatment in 2016, it provided a rare opportunity.

22 Jun 2017

Microscopic fungus exacerbates Crohn's disease symptoms, mice study shows

A microscopic fungus called Candida tropicalis triggered gut inflammation and exacerbated symptoms of Crohn's disease, in a recent study conducted at Case Western Reserve University School of Medicine.

22 Jun 2017

Immune Response News and Research

Scientists develop potential new therapy for targeting skin cancer metastases in the brain

UMMS scientists design human protein-based tumor-targeting MRI contrast agent

JAX researchers explore how dendritic cells promote adaptive immunity to virus

Novel vaccine approach appears to protect fetus from CMV infection, animal study shows

Scientists develop novel DNA-based strategy to protect against broad array of influenza viruses

Study: Personalized neoantigen vaccine stimulates strong anti-tumor response in melanoma patients

Discovery could impact understanding, treatment of autoimmune and inflammatory diseases

Combination treatment could be more effective against common infection

New portable device can quickly find markers of sepsis from single drop of blood

NEI-funded research aims to prevent or reverse progression of cataracts

Scientists find new clues to how RSV causes disease

Proteins impeding antitumor immunity could be 'Achilles heel' of some cancers

Study: Postponing lymph node biopsy after melanoma diagnosis does not affect long-term outcomes

Study develops dissolvable microneedle patches for administering influenza vaccine

New cranberry derivative could help patients dependent on tube feeding

Bandage-strip sized microneedle patches can transform flu vaccination method

Study finds link between upper GI infections and protein implicated in Parkinson’s disease

Four-food elimination diet can resolve symptoms of eosinophilic esophagitis in children

Researchers study Lassa fever patient's immune response and viral persistence

Microscopic fungus exacerbates Crohn's disease symptoms, mice study shows

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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