Immune Response News and Research

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Researchers study Lassa fever patient's immune response and viral persistence

When an American nurse working in West Africa became ill with Lassa fever and was evacuated to the U.S. for treatment in 2016, it provided a rare opportunity.

22 Jun 2017

Microscopic fungus exacerbates Crohn's disease symptoms, mice study shows

A microscopic fungus called Candida tropicalis triggered gut inflammation and exacerbated symptoms of Crohn's disease, in a recent study conducted at Case Western Reserve University School of Medicine.

22 Jun 2017

Scientists develop new algorithm to decipher how immune system recognizes and binds antigens

Scientists from St. Jude Children's Research Hospital and Fred Hutchinson Cancer Research Center have developed an algorithm that functions like a Rosetta Stone to help decipher how the immune system recognizes and binds antigens.

22 Jun 2017

Scientists discover biological fingerprint in children with tuberculosis meningitis

Children with tuberculosis meningitis - a brain and spinal cord infection that leads to disability and death -- have a biological fingerprint that can be used to assess the severity of the condition, help decide the best course of treatment, and provide clues for novel treatments, scientists at the Francis Crick Institute, Imperial College London and the University of Cape Town reveal.

21 Jun 2017

Researchers find new evidence that autoimmunity plays role in Parkinson's disease

Researchers have found the first direct evidence that autoimmunity- in which the immune system attacks the body's own tissues- plays a role in Parkinson's disease, the neurodegenerative movement disorder.

21 Jun 2017

Combination of immunotherapies effective against mouse model of rhabdomyosarcoma

Rhabdomyosarcoma, a cancer made up of cells that normally develop into skeletal muscles, is the most common soft tissue cancer in children. If it is detected early and localized in certain areas, rhabdomyosarcoma is usually curable with traditional therapies like surgery, radiation, and chemotherapy.

20 Jun 2017

Researchers show effective oral treatment option for patients with rheumatoid arthritis

Patients suffering from rheumatoid arthritis are treated for around six months with the standard anti-rheumatic agent methotrexate, to which many patients respond very well.

19 Jun 2017

Viral vectors for gene transfer can travel to distant areas in the brain, study shows

Gene transfer is seen as a hopeful therapy for Alzheimer's and Parkinson's patients. The approach involves using harmless laboratory-produced viruses to introduce important genes into the brain cells.

16 Jun 2017

Wayne State awarded NIH grant to identify new therapeutic targets for bacterial keratitis

Wayne State University recently received a five-year, $1.925 million grant from the National Eye Institute of the National Institutes of Health to test the role of microRNAs (miRNAs) - a newly recognized level of gene expression regulation - in bacterial keratitis – an infection of the cornea caused by bacteria - as well as to identify new therapeutic targets and alternative treatment strategies.

15 Jun 2017

Targeting regulatory T cells could be effective approach to treating cancers, research shows

Researchers at University of Pittsburgh School of Medicine and UPMC have discovered a clue that could unlock the potential of immunotherapy drugs to successfully treat more cancers.

15 Jun 2017

Researchers use quantum dots to decipher design features for new therapies aimed at MS

Researchers in the University of Maryland Fischell Department of Bioengineering (BIOE) Jewell Laboratory are using quantum dots - tiny semiconductor particles commonly used in nanotechnology - to decipher the features needed to design specific and effective therapies for multiple sclerosis (MS) and other autoimmune diseases.

14 Jun 2017

Altered virus could help more patients to become eligible for human gene therapy trials

For many patients, participating in gene therapy clinical trials isn't an option because their immune system recognizes and fights the helpful virus used for treatment.

13 Jun 2017

Dietary practices get reflected in the genes of Europeans, study reveals

A recently published Cornell University study describes how shifts in the diets of Europeans after the introduction of farming 10,000 years ago led to genetic adaptations that favored the dietary trends of the time.

13 Jun 2017

New way to produce protein antigen may lead to preventative vaccine for schistosomiasis

Cornell and Ludwig Institute for Cancer Research scientists have developed a way to produce a protein antigen that may be useful as vaccine for schistosomiasis – a parasitic disease that infects millions of people, mostly in tropical and subtropical climates – according to new research in the journal Protein Expression and Purification, June 2017.

12 Jun 2017

Clinical study shows new mechanism that BCG vaccine uses to reverse advanced type 1 diabetes

Interim results from a FDA-approved clinical trial testing the generic vaccine bacillus Calmette-Guérin (BCG) to reverse advanced type 1 diabetes are being presented at the 75th Scientific Sessions of the American Diabetes Association.

12 Jun 2017

Scientists create 'immunoswitch' particles that slow cancer growth in test animals

Scientists at Johns Hopkins have created a nanoparticle that carries two different antibodies capable of simultaneously switching off cancer cells' defensive properties while switching on a robust anticancer immune response in mice.

8 Jun 2017

Anti-heroin vaccine developed at TSRI proven effective in primate models

A vaccine developed at The Scripps Research Institute (TSRI) to block the "high" of heroin has proven effective in non-human primates. This is the first vaccine against an opioid to pass this stage of preclinical testing.

6 Jun 2017

Greater gut bacteria diversity linked to longer progression-free survival in metastatic melanoma patients

The blend of bacteria in the digestive tract of metastatic melanoma patients is associated with disease progression or delay in patients treated with immunotherapy, researchers at The University of Texas MD Anderson Cancer Center report at the 2017 annual meeting of the American Society of Clinical Oncology.

6 Jun 2017

New breakthrough offers hope for allergy sufferers

Scientists from The University of Queensland believe they have discovered a single treatment that could be a life-long cure for potentially fatal allergies such as asthma.

5 Jun 2017

Gene therapy could give protection from severe allergies

A single treatment giving life-long protection from severe allergies such as asthma could be made possible by immunology research at The University of Queensland.

2 Jun 2017

Immune Response News and Research

Researchers study Lassa fever patient's immune response and viral persistence

Microscopic fungus exacerbates Crohn's disease symptoms, mice study shows

Scientists develop new algorithm to decipher how immune system recognizes and binds antigens

Scientists discover biological fingerprint in children with tuberculosis meningitis

Researchers find new evidence that autoimmunity plays role in Parkinson's disease

Combination of immunotherapies effective against mouse model of rhabdomyosarcoma

Researchers show effective oral treatment option for patients with rheumatoid arthritis

Viral vectors for gene transfer can travel to distant areas in the brain, study shows

Wayne State awarded NIH grant to identify new therapeutic targets for bacterial keratitis

Targeting regulatory T cells could be effective approach to treating cancers, research shows

Researchers use quantum dots to decipher design features for new therapies aimed at MS

Altered virus could help more patients to become eligible for human gene therapy trials

Dietary practices get reflected in the genes of Europeans, study reveals

New way to produce protein antigen may lead to preventative vaccine for schistosomiasis

Clinical study shows new mechanism that BCG vaccine uses to reverse advanced type 1 diabetes

Scientists create 'immunoswitch' particles that slow cancer growth in test animals

Anti-heroin vaccine developed at TSRI proven effective in primate models

Greater gut bacteria diversity linked to longer progression-free survival in metastatic melanoma patients

New breakthrough offers hope for allergy sufferers

Gene therapy could give protection from severe allergies

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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