Immune Response News and Research

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Certain cells from a mother can cause immunity illness in children

Certain cells from a mother persist in their children’s bodies and can provoke an immune response in which the child’s body attacks itself, according to Mayo Clinic research published in the current issue of the Journal of Immunology (http://www.jimmunol.org).

23 Apr 2004

A promising new therapy for rheumatoid arthritis

A promising new therapy for rheumatoid arthritis (RA) developed by researchers at the University of California, San Diego (UCSD) School of Medicine re-educates the body's immune system to prevent an attack against healthy joint tissue.

21 Apr 2004

Possible breakthrough in AIDS and cancer research

Mayo Clinic researchers have found a way to revive immunity in mice that have abnormal or deficient immune systems. The discovery may lead to a means of restoring immunity to individuals with immunodeficiency diseases such as AIDS and cancer.

20 Apr 2004

Functional genomics provide improved drug discovery

Functional genomics and proteomics have been quite successful in identifying functions of potential therapeutic targets such as encoded proteins.

20 Apr 2004

Iron may significantly improve women's attention, short-term and long-term memory

Young women who took iron supplementation for 16 weeks significantly improved their attention, short-term and long-term memory, and their performance on cognitive tasks, even though many were not considered to be anemic when the study began, according to researchers at Pennsylvania State University.

19 Apr 2004

Gene discovery could improve anemia treatment in patients

Patients with inflammatory diseases such as arthritis, chronic infections and some types of cancer, often become anemic – a condition called anemia of chronic disease (ACD). While ACD rarely kills patients, it can make their lives miserable.

18 Apr 2004

New insights into how tumors neutralize CD8 T cells

Scientists have speculated that this may be because the immune response is not strong enough, or because it does not last long enough to have an effect. Hence the increasing efforts to develop cancer vaccines that induce, strengthen, and increase the duration of immunological attack against cancer cells.

16 Apr 2004

Bad hygiene may be good for you

A group of scientists at The Scripps Research Institute have found a connection between poor T cell survival in the body and the development of autoimmunity.

16 Apr 2004

FDA approval for skin cancer cream

3M has received an "approvable" letter from the U.S. Food and Drug Administration (FDA) in response to its supplemental new drug application on Aldara (imiquimod) Cream, 5% for the treatment of superficial basal cell carcinoma (sBCC), a common form of non-melanoma skin cancer.

14 Apr 2004

Growth hormones combat Crohn’s disease, cardiac disorders and improve fertility in invitro fertilisation

New treatments for breast cancer, skin and wound healing and obesity will be revealed at an international conference in Cairns, Australia next week.

13 Apr 2004

New research into Human Papilloma Virus (HPV) and Cervical Cancer

Cervical cancer is the second-most prevalent cancer in women and, despite encouraging improvements in screening leading to earlier detection, cervical cancer still kills many women every year. The risk of cervical cancer is increased by infection with certain types of human papilloma virus (HPV).

12 Apr 2004

Latest developments in prostate cancer research

New research on genes linked to hereditary prostate cancer helps scientists better understand how prostate cancer grows. Tests to find abnormal prostate cancer genes could also help tell which men are at high risk. They could then be tested more often. Further research could provide answers about the chemical changes that lead to prostate cancer. Then, perhaps, we could design drugs to reverse those changes.

12 Apr 2004

Protein kinase complex influences the outer layer of skin to control the eventual shape of the full-grown skeleton and skull

Continuing studies about an important regulatory protein kinase complex called I-kappa-B kinase (or IKK) have now shown that a subunit of IKK – IKK alpha – influences the outer layer of skin in developing mice to control the eventual shape of the full-grown skeleton and skull.

7 Apr 2004

New method to induce embryonic stem cells to develop into bone marrow and blood cells

Researchers at Northwestern University have devised a method to induce embryonic stem cells to develop into bone marrow and blood cells. Injecting the stem cells into the bone marrow cavity of mice whose bone marrow cells had been depleted restored production of blood cells, including cells of the immune system, which normally are created in the bone marrow.

6 Apr 2004

Scientists studying vaccinia virus, a relative of smallpox, have determined that a gene necessary for virus replication also has a key role in turning off inflammation

Scientists at the University of Illinois at Urbana-Champaign studying vaccinia virus, a close relative of smallpox, have determined that a gene necessary for virus replication also has a key role in turning off inflammation, a crucial anti-viral immune response of host cells.

6 Apr 2004

Gene of immune system linked to severe adverse drug reaction called Stevens-Johnson syndrome (SJS)

In a study of Han Chinese patients, researchers have for the first time directly linked a gene of the immune system to a severe adverse drug reaction called Stevens-Johnson syndrome (SJS), according to a Duke University Medical Center medical geneticist and collaborators in Taiwan.

1 Apr 2004

SARS virus vaccine stimulates protective immune response

An experimental vaccine prevents the SARS virus from replicating in laboratory mice, according to a new report in the April 1 issue of Nature. Scientists at the Vaccine Research Center (VRC) of the National Institute of Allergy and Infectious Diseases (NIAID), one of the National Institutes of Health, developed the vaccine. The vaccine was tested in a mouse model of SARS infection recently validated by other NIAID investigators.

31 Mar 2004

Novel vaccine technology to suppress the growth of certain tumors

MedImmune, Inc. and Cerus Corporation have announced preclinical results demonstrating the effectiveness of a novel therapeutic vaccine technology in suppressing the growth of certain tumors.

From Baxter International Inc. 29 Mar 2004

Immunomodulator induces long-term anti-tumor activity

EntreMed, Inc., a clinical-stage biopharmaceutical company developing therapeutic candidates primarily for the treatment of cancer, today reported that three months following administration with ENMD 0996, preclinical animal models showed inhibition of metastases. Data presented demonstrated that ENMD 0996 specifically blocks the activity of basic fibroblast growth factor (FGF-2), a naturally-occurring protein that stimulates angiogenesis, but had no effect on other angiogenesis stimulators.

29 Mar 2004

Renowned researchers, scientists share advances in prevention, diagnosis, therapy

Leading researchers are gathering today for the 95th Annual Meeting of the American Association for Cancer Research (AACR), the premier multidisciplinary assembly, which features the latest developments in basic, prevention, translational and clinical cancer research. The meeting occurs from March 27 – 31, 2004 at the Orlando Convention Center, Fla.

27 Mar 2004