Immunization News and Research

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Novel predictors of severe respiratory syncytial virus infections among infants below the age of one

Researchers examined predictors for hospitalization due to respiratory syncytial virus (RSV) infections to develop a clinical model for guiding immunization and prophylactic treatment of one-year-old infants against RSV infections.

3 Mar 2023

Does the incidence of reported myocarditis or pericarditis after BNT162b2 vaccination vary by age, sex, and inter-dose interval among adolescents aged 12 to 17?

Researchers conducted a population-based cohort study among 12 to 17-year-old adolescents in Ontario, Canada, to estimate the incidence of myocarditis or pericarditis after BNT162b2 vaccination.

3 Mar 2023

New solutions to boost Africa’s vaccine production

The COVID-19 pandemic has highlighted the importance of vaccines in controlling infectious disease in sub-Saharan Africa and renewed interest in vaccine research and development across the continent.

28 Feb 2023

Study findings likely to guide the design of engineered TAPBPR variants with tailored HLA specificity

Researchers at Children's Hospital of Philadelphia (CHOP) have identified variants of a chaperone molecule that optimizes the binding and presentation of foreign antigens across the human population, which could open the door to numerous applications where robust presentation to the immune system is important, including cell therapy and immunization. The findings were published today in Science Advances.

24 Feb 2023

Study highlights COVID-19 vaccine safety among children

Researchers evaluate COVID-19 vaccine-associated serious adverse events following immunization among five- to 17-year-old children.

23 Feb 2023

Is the advantage conferred by the heterologous regimen conserved after a booster dose of mRNA-based COVID-19 vaccine?

Researchers compared the efficacy of a third COVID-19 vaccine dose and that of homologous and heterologous regimens.

23 Feb 2023

Clec9A-RBD immunization could trigger robust and sustained systemic and mucosal immune responses against rapidly evolving SARS-CoV-2 variants

Researchers assessed the impact of a single-dose dendritic cell vaccine candidate on immune responses against SARS-CoV-2.

23 Feb 2023

CDC evaluation of the efficacy of monovalent mRNA vaccines in preventing symptomatic SARS-CoV-2 infection in 3 to 5-year-olds

The complete primary series monovalent mRNA vaccines protect children aged three to five against symptomatic infection for up to four months.

22 Feb 2023

CDC provides vaccine efficacy estimates of Pfizer and Moderna vaccines in kids ages 3-5

Vaccination coverage among infants and children varied according to age, race and ethnicity, jurisdiction, and rural and urban settings

22 Feb 2023

First clinical trial of GABA/GAD focused exclusively on children with recent onset Type 1 diabetes

For the first time, humans with newly diagnosed Type 1 diabetes, or T1D, have received two treatments called GABA and GAD that have shown promise in animal studies and in isolated human pancreas islets. This investigator-initiated clinical trial, published in Nature Communications, focused exclusively on children with recent onset T1D.

22 Feb 2023

RBD-NTD-subunit protein vaccine provides a promising booster vaccination strategy capable of protecting against known SARS-CoV-2 variants

Researchers assessed the impact of SARS-CoV-2 spike NTD incorporation into the RBD protein vaccine.

22 Feb 2023

Adults who received COVID-19 vaccines reported short-term reductions in depressive and anxiety symptoms

A recent study on Swedish adults explored the prevalence of mental health symptoms before and after immunization with coronavirus disease 2019 (COVID-19) vaccines. The study is published in the journal PLOS ONE.

16 Feb 2023

Nirmatrelvir-ritonavir therapy effective against Omicron BA.4/BA.5

Researchers examine non-hospitalized adult patients with COVID-19 treated with nirmatrelvir-ritonavir.

15 Feb 2023

Promising HIV vaccine candidate by Texas Biomed stops the virus upon entry

The National Institutes of Health has awarded $3.8 million to Texas Biomedical Research Institute to further develop a promising HIV vaccine candidate that stops the virus upon entry, before it begins rapidly spreading throughout the body.

15 Feb 2023

Study finds RSV responsible for most infant hospitalizations in the European Union

In a recent study posted to the medRxiv* preprint server, researchers used statistical modeling to estimate hospitalizations due to respiratory syncytial virus (RSV) infections in children under five years of age in 28 nations of the European Union (EU) and Norway.

15 Feb 2023

Changes in SARS-CoV-2 antibody titers after COVID-19 vaccination

Researchers assess longitudinal alterations in SARS-CoV-2 IgG antibody titers after vaccination.

13 Feb 2023

SARS-CoV-2 infection and Ad26.COV2.S vaccination may increase risk of stroke post-vaccination

Researchers examined the factors associated with stroke following coronavirus disease 2019 (COVID-19) vaccination.

13 Feb 2023

The immunogenicity of two leading malaria vaccine candidates delivered as mRNA-LNP vaccines

Researchers evaluated the immunogenicity of two vaccine candidates, Pfs25 and PfCSP, based on the mRNA-lipid nanoparticle (LNP) platform.

13 Feb 2023

Public health agencies turn to locals to extend reach into immigrant communities

When covid-19 vaccines became available, Colorado public health officials initially relied on mass vaccination events publicized through Facebook, email, and texts, and required Coloradans to book appointments online.

10 Feb 2023

Maternal covid-19 vaccination during pregnancy may reduce risk of hospital admission in infants

Two doses of mRNA covid-19 vaccine during pregnancy are highly effective against delta and moderately effective against omicron infection, and are linked to a lower risk of hospital admission in infants under six months of age, finds a Canadian study published by The BMJ today.

9 Feb 2023

Immunization News and Research

Novel predictors of severe respiratory syncytial virus infections among infants below the age of one

Does the incidence of reported myocarditis or pericarditis after BNT162b2 vaccination vary by age, sex, and inter-dose interval among adolescents aged 12 to 17?

New solutions to boost Africa’s vaccine production

Study findings likely to guide the design of engineered TAPBPR variants with tailored HLA specificity

Study highlights COVID-19 vaccine safety among children

Is the advantage conferred by the heterologous regimen conserved after a booster dose of mRNA-based COVID-19 vaccine?

Clec9A-RBD immunization could trigger robust and sustained systemic and mucosal immune responses against rapidly evolving SARS-CoV-2 variants

CDC evaluation of the efficacy of monovalent mRNA vaccines in preventing symptomatic SARS-CoV-2 infection in 3 to 5-year-olds

CDC provides vaccine efficacy estimates of Pfizer and Moderna vaccines in kids ages 3-5

First clinical trial of GABA/GAD focused exclusively on children with recent onset Type 1 diabetes

RBD-NTD-subunit protein vaccine provides a promising booster vaccination strategy capable of protecting against known SARS-CoV-2 variants

Adults who received COVID-19 vaccines reported short-term reductions in depressive and anxiety symptoms

Nirmatrelvir-ritonavir therapy effective against Omicron BA.4/BA.5

Promising HIV vaccine candidate by Texas Biomed stops the virus upon entry

Study finds RSV responsible for most infant hospitalizations in the European Union

Changes in SARS-CoV-2 antibody titers after COVID-19 vaccination

SARS-CoV-2 infection and Ad26.COV2.S vaccination may increase risk of stroke post-vaccination

The immunogenicity of two leading malaria vaccine candidates delivered as mRNA-LNP vaccines

Public health agencies turn to locals to extend reach into immigrant communities

Maternal covid-19 vaccination during pregnancy may reduce risk of hospital admission in infants

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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