Immunodeficiency News and Research

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Immunodeficiency (or immune deficiency) is a state in which the immune system's ability to fight infectious disease is compromised or entirely absent.

New discoveries in treatment for patients with non-Hodgkin's lymphoma

Three scientific studies - each highlighting new discoveries in treatment for patients with non-Hodgkin's lymphoma - were announced at the Society of Nuclear Medicine's 52nd Annual Meeting June 18–22 in Toronto.

20 Jun 2005

Prototype drug shows promise in slowing replication of the virus responsible for SARS

A prototype drug created by researchers at the University of Illinois at Chicago shows promise in slowing replication of the virus responsible for severe acute respiratory syndrome, or SARS.

8 Jun 2005

Risk factors for tuberculosis in the United States overlap with many of the risk factors associated with persistent homelessness

...including being male or having a history of incarceration or substance abuse, according to a report in the June 8 issue of JAMA, a theme issue on tuberculosis.

8 Jun 2005

Gene therapy for arthritis is both feasible and safe

Gene therapy for arthritis and other non-terminal, debilitating conditions and diseases is both feasible and safe, report researchers who conducted the world's first such test on the approach in patients with advanced rheumatoid arthritis.

6 Jun 2005

HIV protease inhibitors block programmed cell death in vivo

The immunodeficiency that arises in HIV may be due to excessive programmed cell death of immune CD4 T cells.

3 Jun 2005

Research provides roadmap for the development of human therapies for cytomegalovirus (CMV)

McGill University Health Centre (MUHC) researchers have defined genetic resistance to the widespread virus, cytomegalovirus (CMV)--a member of the viral group that causes some of the world's most prevalent diseases, such as herpes, chicken pox and mononucleosis.

26 May 2005

Antiretroviral therapy may prevent excess risk of some cancers in people with HIV

In people infected with human immunodeficiency virus (HIV), highly active anti-retroviral therapy (HAART) may prevent most excess cases of Kaposi sarcoma and non-Hodgkin lymphoma, according to a new study in the March 16 issue of the Journal of the National Cancer Institute.

18 May 2005

Antibiotic minocycline might help alleviate HIV's negative effects on the brain and central nervous system

By studying animals, Johns Hopkins researchers have discovered that the antibiotic minocycline might help alleviate HIV's negative effects on the brain and central nervous system, problems that can develop even though antiretroviral therapy controls the virus elsewhere in the body.

1 May 2005

HIV epidemic among young men unabated because many are unaware they are infected

U.S. health officials say many young gay and bisexual men who are HIV-positive are unaware they have the virus.

26 Apr 2005

As syphilis rates increase in Los Angeles County, new study suggests the disease is increasing HIV rates

The syphilis epidemic among men who have sex with men in Los Angeles County may be contributing to rates of HIV in this population, according to a new report published in the Journal of Acquired Immune Deficiency Syndrome.

23 Apr 2005

Clinical study of MDX-010/MDX-1379 combination shows durable responses in patients with metastatic melanoma

Medarex, Inc. and Bristol-Myers Squibb Company announced today that complete or partial responses in seven of 56 patients with metastatic melanoma showed durability ranging from four months to the longest still ongoing at over 34 months, with five of the seven responses ongoing for more than two years.

20 Apr 2005

Key discovery about non-Hodgkin lymphoma

There is a surprise benefit to being either an only child, the oldest sibling or even enduring some allergies – you are significantly less likely to develop non-Hodgkin lymphoma (NHL), according to new research from the University of New South Wales (UNSW).

19 Apr 2005

Method of gene therapy accurately corrects mutations in disease-causing genes

Harnessing the strength of a natural process that repairs damage to the human genome, a researcher from UT Southwestern Medical Center has helped establish a method of gene therapy that can accurately and permanently correct mutations in disease-causing genes.

5 Apr 2005

DNA repair kit announced by scientists

A study by scientists at Sangamo BioSciences, Inc. has demonstrated the use of the Company's zinc finger DNA-binding protein (ZFP) technology to achieve highly efficient, permanent correction of a disease-causing gene in primary human cells.

5 Apr 2005

Method of gene therapy that can accurately and permanently correct mutations in disease-causing genes

4 Apr 2005

New chemicals to inhibit HIV infection

In corporation with peers from the Mount Sinai School of Medicine, New York University, researchers from the University of Science and Technology of China (USTC), a CAS affiliate, have come up with new chemical inhibitors against HIV reproduction, marking a significant progress in the development of anti-AIDS drugs based on natural host resistance.

4 Apr 2005

Primary health care providers should incorporate HIV testing into routine patient care for all sexually active individuals

Primary health care providers should incorporate human immunodeficiency virus (HIV) testing into routine patient care for all sexually active individuals, regardless of risk factors, say a group of physician/researchers at Emory University School of Medicine, Brown Medical School, and the Johns Hopkins School of Medicine.

30 Mar 2005

HIV patients who delay seeking care are much sicker when they begin care

Patients recently diagnosed with human immunodeficiency virus (HIV) are significantly more likely to seek medical treatment if they are followed even briefly by a case manager, according to findings of the national Antiretroviral Treatment Access Study (ARTAS).

30 Mar 2005

AIDS virus initially more destructive than first thought

The AIDS virus destroys more than half of the immune cells that might recognize and help fight it, within days of infection according to US researchers, and this revelation might necessitate a re-evaluation of how the deadly infection should be tackled.

28 Mar 2005

New study to evaluate Pegasys and Copegus to treat hepatitis C in liver transplant patients

Roche has initiated a new study to evaluate treatment strategies to reduce post-transplant recurrence of hepatitis C infection with the most prescribed hepatitis C treatment combination in the U.S., Pegasys (peginterferon alfa-2a) and Copegus (ribavirin, USP).

21 Mar 2005