Immunodeficiency News and Research

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Immunodeficiency (or immune deficiency) is a state in which the immune system's ability to fight infectious disease is compromised or entirely absent.

AIDS virus initially more destructive than first thought

The AIDS virus destroys more than half of the immune cells that might recognize and help fight it, within days of infection according to US researchers, and this revelation might necessitate a re-evaluation of how the deadly infection should be tackled.

28 Mar 2005

New study to evaluate Pegasys and Copegus to treat hepatitis C in liver transplant patients

Roche has initiated a new study to evaluate treatment strategies to reduce post-transplant recurrence of hepatitis C infection with the most prescribed hepatitis C treatment combination in the U.S., Pegasys (peginterferon alfa-2a) and Copegus (ribavirin, USP).

21 Mar 2005

Antiretroviral therapy may prevent some cancers in people with HIV

In people infected with human immunodeficiency virus (HIV), highly active antiretroviral therapy (HAART) may prevent most excess cases of Kaposi sarcoma and non-Hodgkin lymphoma, according to a new study in the March 16 issue of the Journal of the National Cancer Institute.

15 Mar 2005

HIV-1 spread through six transmission lines in the UK

Contrary to the prevailing belief that the HIV epidemic in the UK can be traced back to one source, a new study suggests that HIV spread via at least six independent virus introductions and subsequent transmission chains.

14 Mar 2005

Research could lead to new drugs that combat HIV infection by shutting down the virus's assembly lines

After infecting a susceptible cell, the human immunodeficiency virus hijacks that cell's normal machinery to produce carbon copies of itself. New HIV particles roll off the cellular assembly lines, burst like bubbles out of the cell, and float off to invade other cellular factories.

14 Mar 2005

HIV is not an independent risk factor for severe heart disease

Infection with human immunodeficiency virus (HIV) is no longer an automatic death sentence, thanks to the use of highly active anti-retroviral therapy (HAART).

8 Mar 2005

Study looks at the ability of some monkey species to resist developing AIDS

The Tulane National Primate Research Center received a five-year grant of more than $2 million from the National Institute of Allergy and Infectious Diseases to study the ability of some monkey species to resist developing AIDS.

7 Mar 2005

Scientists gain new insight into DiGeorge syndrome

A collaboration of European scientists has uncovered new insight into the most common chromosomal microdeletion syndrome in humans.

28 Feb 2005

Virologists make major step towards understanding the process of HIV infection

A working group of virologists headed by Professor Hans-Georg Kräusslich at Heidelberg University Hospitals, jointly with Professor Hanswalter Zentgraf, Division of Applied Tumor Virology of the Deutsches Krebsforschungszentrum (German Cancer Research Center, DKFZ), have been the first to label Human Immunodeficiency Viruses (HIV) for visual investigations without inhibiting the functional characteristics of the virus.

28 Feb 2005

New study following 12,574 individuals over the course of three years of HAART

Although clinical progression to AIDS of patients infected with Human immunodeficiency virus (HIV) has declined since the introduction of Highly Active Antiretroviral Therapy (HAART), there is little data on the changes in incidence of AIDS-defining events during the first few years of therapy.

28 Feb 2005

Scientists identify immune-system mutation

A team of Fox Chase Cancer Center scientists led by immunologist Dietmar J. Kappes, Ph.D., has identified the genetic mutation that keeps a mouse strain from developing white blood cells, or lymphocytes, called helper T cells. The report by Kappes and his colleagues appears in the Feb. 24 issue of Nature.

27 Feb 2005

Gel provides protection from HIV and herpes

Mount Sinai School of Medicine researchers demonstrated that a gel applied in the vagina provides protection from both the human immunodeficiency virus (HIV) and the herpes simplex Virus. The study, presented at the 12th Conference on Retroviruses and Opportunistic Infections, is the first to show that a gel can retain anti-viral activity within the human vagina.

27 Feb 2005

Microsoft combs through millions of strains of human immunodeficiency virus (HIV)

Microsoft Research has pioneered promising new ways to combat one of humankind's most deadly viruses with advanced software typically used to analyze large computer databases and complex digital images, or to separate spam from legitimate e-mail.

23 Feb 2005

Antibody that neutralizes most HIV strains

A group of scientists from The Scripps Research Institute and several other institutions has solved the structure of a rare human antibody that broadly neutralizes human immunodeficiency virus (HIV), which causes acquired immunodeficiency syndrome (AIDS).

22 Feb 2005

New 3-DCR HIV strain does not respond to three classes of anti-retroviral medication

A highly resistant strain of rapidly progressive human immunodeficiency virus (HIV) has been diagnosed for the first time in a New York City resident who had not previously undergone antiviral drug treatment, according to the Department of Health and Mental Hygiene (DOHMH).

13 Feb 2005

Need for routine voluntary screening for HIV

A new cost-effectiveness analysis has led researchers from Duke University Medical Center and the Veterans Affairs (VA) Palo Alto Health Care System to recommend that routine voluntary screening for HIV

10 Feb 2005

Researchers have discovered an ample source of stem cells in an uncharted part of the umbilical cord

The study, published in the February issue of Stem Cells, outlines how researchers discovered that the jelly-like connective tissue surrounding the blood vessels of the human umbilical cord, the so-called "Wharton's Jelly," is rich in mesenchymal progenitor cells – cells that generate bone, cartilage and other tissues – and can be harvested to generate an abundant supply in a short amount of time.

9 Feb 2005

HIV-infected parents peport limiting physical contact with their children

Over one-fourth of HIV-infected parents reported avoiding certain physical interactions, like hugging or kissing, with their children due to a fear of transmitting the disease or of contracting an infection from them, according to an article in the February issue of Archives of Pediatrics & Adolescent Medicine.

7 Feb 2005

Important clue to understanding the origins of the AIDS epidemic

Medical Research Council (MRC) scientists have uncovered an important clue to understanding the origins of the AIDS epidemic. The work suggests that harnessing natural mechanisms of resistance to HIV infection might provide new methods for combating AIDS.

12 Jan 2005