Immunoglobulin News and Research

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A SARS-CoV-2 spike-targeting bispecific T-cell engager strategy for controlling SARS-CoV-2 infection

Researchers described a novel strategy for controlling severe acute respiratory syndrome coronavirus 2.

5 Jun 2023

MFAP5, a microfibril-associated protein, unveiled as key player in scar formation and wound healing

MFAP5, a microfibril-associated protein, plays a significant role in wound healing by regulating fibroblast function, collagen deposition, and angiogenesis, suggesting its potential as a modulator of scar formation.

1 Jun 2023

Key insights into immune responses after COVID-19 vaccination in Indigenous people

Researchers evaluated immune responses to COVID-19 BNT162b2 mRNA vaccinations among Indigenous Australian First Nations (FN) individuals by comorbidity and ethnicity.

1 Jun 2023

What was SARS-CoV-2 antibody seroprevalence in Italian blood donors?

Researchers evaluated titers and types of severe acute respiratory syndrome coronavirus 2 antibodies in voluntary blood donors.

1 Jun 2023

Dutch scientists unveil the integral role of CD5L protein in IgM structure and function

Researchers in the Netherlands assessed the structure of human circulatory IgM and its relationship with the small CD5L protein.

31 May 2023

Green Mediterranean diet reshapes DNA methylation, boosts metabolism

Study explores the effects of a green-MED diet enriched in polyphenols and reduced in red/processed meat on the methylome and transcriptome levels. It aims to uncover the molecular mechanisms underlying the observed metabolic improvements.

30 May 2023

Study shows how IgA acts as a "tuner" to keep the immune system in check

IgA deficiency is the most common primary immune deficiency worldwide, but its presentation has puzzled physcians and researchers.

26 May 2023

The potential clinical benefit of the Multabody platform as a therapeutic for SARS-CoV-2

The potential clinical benefit of the Multabody platform as a therapeutic for SARS-CoV-2.

26 May 2023

T-cell-inducing mRNA COVID-19 vaccine improves effectiveness

Researchers develop a lipid nanoparticle-formulated mRNA-based antigen encoding three SARS-CoV-2 peptides derived from non-structural proteins.

25 May 2023

National-level comprehensive mapping of high-fatality SARS-CoV-2 outbreaks in nursing homes

Researchers analyzed data from three SARS-CoV-2 outbreaks among nursing homes in Belgium.

24 May 2023

Cross-reactivity between Epstein-Barr virus and protein in multiple sclerosis sheds light on disease development

Research uncovers the association between multiple sclerosis (MS) and antibody reactivity to specific amino acids in CRYAB, along with the increased risk when combined with high EBNA1 responses. The study provides evidence of antibody and T cell cross-reactivity between EBNA1 and CRYAB, highlighting the role of EBV adaptive immune responses in MS development.

21 May 2023

Breast milk shields newborns: COVID-19 antibodies and microbiota from vaccinated mothers provide dual defense

Research paper discusses the differences in microbiota between high and low IgA subjects after the second dose of the COVID-19 vaccine. The study found that certain microbial features in breast milk can predict levels of anti-SARS-CoV-2 antibodies in breast milk one week post-second dose.

21 May 2023

Synthetic delivery vector STxB induces mucosal immunity against viral antigens

Research describes the development of a synthetic delivery vector called STxB for mucosal vaccination. It induces mucosal immunity, including resident memory CD8+ T cells and IgA antibodies, against antigens derived from mucosal viruses when administered intranasally in mice.

21 May 2023

A novel role for macrophage-activation signaling in orchestrating the recruitment process in response to the SARS-CoV-2 spike protein

Researchers derived peptides from the SARS-CoV-2 spike protein to assess COVID-19-associated inflammatory changes using zebrafish models.

19 May 2023

Novel antibodies target human receptors to neutralize SARS-CoV-2 variants and future sarbecoviruses

Researchers generated six human monoclonal antibodies that prevented infection.

17 May 2023

New process for automated and highly accurate reporting of NGS-based clonality testing

A new research paper was published in Oncotarget's Volume 14 on May 12, 2023, entitled, "Development and implementation of an automated and highly accurate reporting process for NGS-based clonality testing."

16 May 2023

Study indicates that the Omicron wave and the rollout of vaccines led to almost 100% seropositivity and boosted anti-spike IgG titers in children and adolescents

Researchers discussed the presence of persistent humoral immunity among children and adolescents during COVID-19.

15 May 2023

Breast milk microbes shape infant gut health

Research investigates the association between the microbial communities in human milk and infant gut. The study found that milk microbial communities have a long-term effect on the infant gut microbiome both through sharing of microbes and other molecular mechanisms.

9 May 2023

SARS-CoV-2 infection leads to higher IgA levels in breast milk than vaccination

Researchers explore the presence and effectiveness of SARS-CoV-2 antibodies in breastmilk following infection, vaccination, or both.

8 May 2023

The safety and efficacy of FINLAY-FR-2/1A, a new protein-based COVID-19 vaccine

Research paper reports the results of a phase 3 clinical trial evaluating the efficacy and safety of the FINLAY-FR-2 and FINLAY-FR-1A vaccines in Iranian adults.

7 May 2023

Immunoglobulin News and Research

A SARS-CoV-2 spike-targeting bispecific T-cell engager strategy for controlling SARS-CoV-2 infection

MFAP5, a microfibril-associated protein, unveiled as key player in scar formation and wound healing

Key insights into immune responses after COVID-19 vaccination in Indigenous people

What was SARS-CoV-2 antibody seroprevalence in Italian blood donors?

Dutch scientists unveil the integral role of CD5L protein in IgM structure and function

Green Mediterranean diet reshapes DNA methylation, boosts metabolism

Study shows how IgA acts as a "tuner" to keep the immune system in check

The potential clinical benefit of the Multabody platform as a therapeutic for SARS-CoV-2

T-cell-inducing mRNA COVID-19 vaccine improves effectiveness

National-level comprehensive mapping of high-fatality SARS-CoV-2 outbreaks in nursing homes

Cross-reactivity between Epstein-Barr virus and protein in multiple sclerosis sheds light on disease development

Breast milk shields newborns: COVID-19 antibodies and microbiota from vaccinated mothers provide dual defense

Synthetic delivery vector STxB induces mucosal immunity against viral antigens

A novel role for macrophage-activation signaling in orchestrating the recruitment process in response to the SARS-CoV-2 spike protein

Novel antibodies target human receptors to neutralize SARS-CoV-2 variants and future sarbecoviruses

New process for automated and highly accurate reporting of NGS-based clonality testing

Study indicates that the Omicron wave and the rollout of vaccines led to almost 100% seropositivity and boosted anti-spike IgG titers in children and adolescents

Breast milk microbes shape infant gut health

SARS-CoV-2 infection leads to higher IgA levels in breast milk than vaccination

The safety and efficacy of FINLAY-FR-2/1A, a new protein-based COVID-19 vaccine

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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