Immunosuppression News and Research

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Immunosuppression involves an act that reduces the activation or efficacy of the immune system. Some portions of the immune system itself have immuno-suppressive effects on other parts of the immune system, and immunosuppression may occur as an adverse reaction to treatment of other conditions.

Study identifies risk factors for severe COVID-19 in hospitalized children in Canada

Researchers evaluated the risk factors for severe COVID-19 among hospitalized children in Canada.

12 Apr 2022

Researchers design RNA molecules for delivering therapies directly to beta cells

Investigators at the University of Miami Miller School of Medicine have designed RNA molecules that home to human pancreatic beta cells, the cells that produce insulin and are destroyed in patients with type 1 and type 2 diabetes.

7 Apr 2022

Patient outcomes after influenza, RSV, or SARS-CoV-2 hospitalization

A recent study posted to the medRxiv* preprint server investigated the elements that predicted all-cause mortality among individuals hospitalized due to influenza, respiratory syncytial virus (RSV), or severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

7 Apr 2022

Evaluating serological responses to repeated COVID-19 vaccination in kidney transplant recipients

Researchers analyzed whether repeated vaccinations against COVID-19 increase serological response in non-responding kidney transplant recipients.

29 Mar 2022

New pancreatic islet cryopreservation protocol could pave the way for diabetes cure

Engineering and medical researchers at the University of Minnesota Twin Cities and Mayo Clinic have developed a new process for successfully storing specialized pancreatic islet cells at very low temperatures and rewarming them, enabling the potential for on-demand islet transplantation.

24 Mar 2022

SARS-CoV-2 mRNA vaccines may prevent COVID-19-associated mechanical ventilation and death

Researchers performed a case-control study to evaluate the effectiveness of SARS-CoV-2 messenger ribonucleic acid vaccines.

23 Mar 2022

Frail and older males more vulnerable to COVID-19 than females

Researchers evaluated the association of biological sex, frailty, and age with the vaccine-elicited immunity against SARS-CoV-2.

17 Mar 2022

Viral load reduction effectiveness of SARS-CoV-2 BNT162b2 mRNA booster vaccine wanes with time

In a new study, researchers conducted a retrospective analysis of the SAR-CoV-2 reverse transcriptase - quantitative polymerase chain reaction test measurements.

9 Mar 2022

Relationship between immunological responses in the acute phase of SARS-CoV-2 infection and long-term cognitive deficits

A recent study reported that monocytosis during the acute phase of coronavirus disease 2019 could forecast anosognosia in long COVID.

8 Mar 2022

Researchers develop scoring tools to determine hospitalization and mortality risk in COVID-19 patients

Researchers conducted a large retrospective study on a cohort of severe acute respiratory syndrome coronavirus 2 SARS-CoV-2 patients, developing and validating a simple and precise scoring tool to risk stratify COVID-19 ambulatory and emergency department patients for subsequent hospitalizations and mortalities.

8 Mar 2022

Study explores COVID-19 vaccine effectiveness in ankylosing spondylitis patients

Researchers estimated the immunogenicity of SARS-CoV-2 vaccination in a Belgian cohort of patients with ankylosing spondylitis.

7 Mar 2022

Third dose of COVID mRNA vaccine safe and effective in kidney transplant patients

An new study reports that a third dose of the Pfizer BNT162b2 vaccine produces high levels of anti-spike IgG antibodies in kidney transplant recipients.

6 Mar 2022

Adenosine receptor agonists provide therapeutic target in mouse SARS-CoV-2 infection

A new study describes the efficacy of adenosine receptor agonists in the treatment of SARS-CoV-2 infection.

2 Mar 2022

Declining immune responses against SARS-CoV-2 variants in dialysis patients post-vaccination

Researchers examined systemic B and T cell responses 16 weeks after BNT162b2 vaccination, and the potency of vaccine-induce neutralizing antibodies, in hemodialysis patients and healthcare workers with no comorbidities.

25 Feb 2022

Study on Omicron related mortality in cancer patients during recent COVID wave

A recent pre-proof study published in the journal Cancer Cell assessed the CFR of cancer patients during the third wave of the coronavirus disease 2019 (COVID-19) pandemic caused by the SARS-CoV-2 Omicron variant.

23 Feb 2022

Merkel cell carcinoma has a higher post-treatment recurrence rate than other skin cancers

Patients treated for Merkel cell carcinoma (MCC) face a five-year recurrence rate of 40%-;markedly higher than the recurrence rates for melanoma and other skin cancers, according to research published today in JAMA Dermatology.

23 Feb 2022

Study demonstrates that TMPRSS2, which is key to SARS-CoV-2 cell entry, is a tumor suppressor

The role played by the host enzyme TMPRSS2 in infection and cancer is the focus of a new study.

23 Feb 2022

REGEN-COV antibody combination to prevent COVID-19 severity

A new study assessed the effectiveness of REGEN-COV, a combination of casirivimab and imdevimab monoclonal antibodies, in the prevention of COVID-19 disease severity.

22 Feb 2022

Prevalence of chemosensory loss induced by SARS-CoV-2 Omicron variant in Italy

Researchers conducted a prospective cohort study to determine the prevalence of chemosensory dysfunction in mild to moderate COVID-19 patients in Italy.

22 Feb 2022

Drugs that increase fetal hemoglobin levels may help people with sickle cell disease

Sickle cell anemia is an inherited blood disorder where red blood cells become sickle/crescent shaped. It causes frequent infections, swelling in the hands and legs, pain, severe tiredness and delayed growth or puberty.

18 Feb 2022

Immunosuppression News and Research

Further Reading

Study identifies risk factors for severe COVID-19 in hospitalized children in Canada

Researchers design RNA molecules for delivering therapies directly to beta cells

Patient outcomes after influenza, RSV, or SARS-CoV-2 hospitalization

Evaluating serological responses to repeated COVID-19 vaccination in kidney transplant recipients

New pancreatic islet cryopreservation protocol could pave the way for diabetes cure

SARS-CoV-2 mRNA vaccines may prevent COVID-19-associated mechanical ventilation and death

Frail and older males more vulnerable to COVID-19 than females

Viral load reduction effectiveness of SARS-CoV-2 BNT162b2 mRNA booster vaccine wanes with time

Relationship between immunological responses in the acute phase of SARS-CoV-2 infection and long-term cognitive deficits

Researchers develop scoring tools to determine hospitalization and mortality risk in COVID-19 patients

Study explores COVID-19 vaccine effectiveness in ankylosing spondylitis patients

Third dose of COVID mRNA vaccine safe and effective in kidney transplant patients

Adenosine receptor agonists provide therapeutic target in mouse SARS-CoV-2 infection

Declining immune responses against SARS-CoV-2 variants in dialysis patients post-vaccination

Study on Omicron related mortality in cancer patients during recent COVID wave

Merkel cell carcinoma has a higher post-treatment recurrence rate than other skin cancers

Study demonstrates that TMPRSS2, which is key to SARS-CoV-2 cell entry, is a tumor suppressor

REGEN-COV antibody combination to prevent COVID-19 severity

Prevalence of chemosensory loss induced by SARS-CoV-2 Omicron variant in Italy

Drugs that increase fetal hemoglobin levels may help people with sickle cell disease

Exploring the intersection of biology and proteomics

Unlocking the Secrets of Multiple Sclerosis Progression: Brain-Immune Cell Communication

Passing on Polycystic Ovary Syndrome: Health risks for male offspring of women with PCOS

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