In Utero News and Research

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SARS-CoV-2 infection and immunity in pregnancy and fetal development

A review conducted by a team of researchers from the Icahn School of Medicine at Mount Sinai, the University of Colorado, and Active Motif, Incorporated compiles information on SARS-CoV-2 virology, in utero transmission from infected pregnant mothers to fetuses, new findings on possible methods of SARS-CoV-2 cellular trafficking through exosomes, and the transcriptomic effects of SARS-CoV-2 infection, in order to inform future studies aimed at a better understanding of COVID-19 and the development of therapeutic solutions against SARS-CoV-2.

30 Dec 2021

Hormone levels in the womb before birth linked to the risk of developing migraine in adulthood

Hormone levels in the womb before birth have been potentially linked to the risk of developing migraine in adulthood, reveals a new study of genetic and environmental information from the world's largest database of twins.

16 Dec 2021

Infantile cataracts are more common and problematic than thought

Three days after Canyon Brown was born, the attending pediatrician discovered a problem.

8 Dec 2021

Cannabis vapor exposure generationally affects sperm counts and motility in mice

An intense but short-term exposure to cannabis vapor lowered sperm counts and slowed sperm movement, or motility, not only in the directly exposed male mice but also in their sons.

2 Dec 2021

Study uncovers major disparities in preferred HIV medication uptake in low- and middle-income countries

A new study uncovered large and persistent disparities by sex and age in the uptake of a preferred HIV medication in low- and middle-income countries, potentially subjecting some women to worse HIV treatment outcomes if the situation is not corrected quickly.

30 Nov 2021

U of U Health scientists lead new studies investigating the long-term effects of COVID-19

University of Utah Health scientists are on the leading edge of a pair of large studies investigating the long-term effects of COVID-19.

30 Oct 2021

Breastfeeding and later introduction to gluten may have a protective effect against type 1 diabetes

Research on the role of diet in the development of type 1 diabetes is generally of low evidence, but there are some high-quality studies indicating that longer breastfeeding and later introduction to gluten may reduce the risk of disease.

18 Oct 2021

Mothers pass on the legacy of stress exposure to future generations

A mother's response to stress can even influence her grandchildren. Biologists at the University of Iowa found that roundworm mothers subjected to heat stress passed, under certain conditions and through modifications to their genes, the legacy of that stress exposure not only to their offspring but even to their offspring's children.

13 Oct 2021

An investigation of SARS-CoV-2 infection in diabetic pregnancies

Researchers discuss the basic and clinical science of the potential inter-relationships between diabetes mellitus and COVID-19 in pregnancies.

11 Oct 2021

More severe SARS-CoV-2 infection associated with greater risk of preterm birth

Researchers at the Wayne State University School of Medicine and the National Institutes of Health's Perinatology Research Branch in Detroit have discovered that the more severely infected with COVID-19 a mother is, the more likely she is to experience preterm birth.

8 Oct 2021

Research on twins indicates strong genetic influences in COVID-19

A new study discusses the strong possibility of multifactorial causation for SARS-CoV-2 infection using data from twin studies.

6 Oct 2021

COVID-19 infection during pregnancy increases risk of developing pre-eclampsia, study finds

A newly published study found that women who contract COVID-19 during pregnancy are at significantly higher risk of developing pre-eclampsia, the leading cause of maternal and infant death worldwide.

22 Sep 2021

Children with CZS-associated microcephaly show severe neurodevelopmental impairments

At age two, children who were born with neurological abnormalities due to congenital Zika Virus (ZIKV) have a range of neurodevelopmental profiles that can be tracked using a routine neurological assessment, according to a new study published this week in the open-access journal PLOS ONE by Dr. Albert Ko of Yale University, US and Dr. Federico Costa of The Federal University of Bahia, Brazil, and their colleagues.

15 Sep 2021

Maternal obesity during pregnancy may heighten the risk of colorectal cancer in adult offspring

Infants whose mothers were obese during pregnancy may have a heightened risk of developing colorectal cancer later in life, according to new research led by public health experts at The University of Texas Health Science Center at Houston.

27 Aug 2021

Mild maternal infections can have permanent impacts on offspring immunity

During pregnancy, mild infections in the mother can have permanent and tissue-specific impacts on offspring immunity, according to a new study in mice.

27 Aug 2021

Report reveals rising rates of diabetes among youth in the United States

Diagnosed cases of type 1 and type 2 diabetes are surging among youth in the United States. From 2001 to 2017, the number of people under age 20 living with type 1 diabetes increased by 45%, and the number living with type 2 diabetes grew by 95%.

24 Aug 2021

Maternal obesity may raise the risk of bowel cancer in adult offspring

An obese mum-to-be may be raising the risk of bowel cancer in her adult children, suggests research of more than 18,000 mother and child pairs, published online in the journal Gut.

24 Aug 2021

Study finds unacceptably alarming rise in gestational diabetes among U.S. women

The rate of gestational diabetes has shot up 30 percent in young U.S. women over the past decade and more than doubled in U.S. women who identify as Asian-Indian compared with non-Hispanic White women, reports a new Northwestern Medicine study published in JAMA.

23 Aug 2021

Researchers develop a cell culture test to detect substances that harm the placenta and embryo

Researchers at ETH Zurich have developed a cell culture test to detect substances that are directly or indirectly harmful to embryos. Based on an existing test used for developing new drugs and chemicals, the augmented version is designed to help reduce the number of animal experiments.

22 Jul 2021

Early life exposure to antibiotics could alter brain development

Antibiotic exposure early in life could alter human brain development in areas responsible for cognitive and emotional functions, according to a Rutgers researcher.

14 Jul 2021