Infectious Diseases News and Research

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International community, U.S. should increase resources, mandate for fighting NCDs in developing world

In this Foreign Affairs essay, Thomas Bollyky, a senior fellow for global health, economics and development at the Council on Foreign Relations, examines the increase of non-communicable diseases (NCDs) in the developing world.

10 May 2012

Researchers use clever screening methods to speed vaccine production

Infectious diseases-both old and new-continue to exact a devastating toll, causing some 13 million fatalities per year around the world. Vaccines remain the best line of defense against deadly pathogens and now Kathryn Sykes and Stephen Johnston, researchers at Arizona State University's Biodesign Institute, along with co-author Michael McGuire from the University of Texas Southwestern Medical Center are using clever functional screening methods to attempt to speed new vaccines into production that are both safer and more potent.

10 May 2012

IDRI, Aeras partner to develop new TB vaccine candidate

Aeras and the Infectious Disease Research Institute (IDRI) announce today a new agreement to conduct joint development activities with respect to IDRI's novel tuberculosis vaccine candidate. This collaboration reflects the missions of the two non-profit product development partnerships to use cutting-edge science to develop products that address critical diseases of underserved populations around the world, including tuberculosis.

10 May 2012

Inovio first quarter total revenue decreases to $1.7 million

Inovio Pharmaceuticals, Inc. today reported financial results for the quarter ended March 31, 2012.

10 May 2012

One in six cancer cases worldwide related to preventable or curable infections

New research shows that one in six cancers - amounting to two million a year globally - are caused by largely treatable or preventable infections.

9 May 2012

Reusable grocery bag can play a role in spreading norovirus infection

Oregon investigators recently mapped the trail of an outbreak of a nasty stomach bug among participants in a girls' soccer tournament to a reusable open top grocery bag stored in a hotel bathroom. Their findings, which illustrate the role that inanimate objects can play in spreading norovirus infection, appear in The Journal of Infectious Diseases.

9 May 2012

Advaxis commences enrollment in ADXS-HPV Phase 1/2 study for head and neck cancer

Advaxis, Inc.,, a leader in developing the next generation of immunotherapies for cancer and infectious diseases, announced that two patients have been enrolled into REALISTIC, a Phase 1/2 study being sponsored by Cancer Research UK (CRUK) to investigate the use of ADXS-HPV for the treatment of HPV positive head and neck cancer. HPV is associated with 40-70% of head and neck cancers.

8 May 2012

Certain males at higher risk of infection after receiving experimental HIV vaccine

A long-term follow-up analysis of participants in the Step Study, an international HIV-vaccine trial, has confirmed that certain subgroups of male study participants were at higher risk of becoming infected after receiving the experimental vaccine compared to those who received a placebo.

8 May 2012

Metformin blocks uveitis in laboratory rats

University of Texas Medical Branch at Galveston researchers have discovered that a drug already prescribed to millions of people with diabetes could also have another important use: treating one of the world's leading causes of blindness.

8 May 2012

Cholera strain in Haiti evolving, CDC reports

"The cholera strain in Haiti is evolving, researchers reported Thursday, a sign that it may be taking deeper root in the nation less than two years after it appeared and killed thousands of people," the Associated Press/USA Today reports.

8 May 2012

VOA News examines South Africa's rural public health sector

VOA News features a five-part series on South Africa's rural public health sector, which the news service writes is "plagued by a high burden of infectious diseases, severe doctor and nurse shortages, lack of medicines and essential medical equipment and incompetent management," resulting in high patient death rates.

8 May 2012

Meningitis B vaccine on the horizon

Meningitis B is particularly dangerous for children, leading to 120 deaths in the UK every year. There are around 1,200 new cases of meningitis B every year. Around 1 in 10 victims die and another 15 per cent are left with permanent disabilities - often limbs have to be amputated due to blood poisoning. The infection causes inflammation of the membranes surrounding the spinal cord and brain. Symptoms include a severe headache, vomiting, a rash, sensitivity to light and a stiff neck.

8 May 2012

NovaDigm reports positive data from Phase 1 NDV-3 vaccine program

NovaDigm Therapeutics, a company developing innovative vaccines for fungal and bacterial infections, today announced the presentation of positive data for its NDV-3 vaccine program in a second Phase 1 study.

7 May 2012

NFID to host 15th Annual Conference on Vaccine Research from May 7–9

The National Foundation for Infectious Diseases will host the 15th Annual Conference on Vaccine Research, May 7–9, 2012, at the Hyatt Regency Inner Harbor in Baltimore, MD.

5 May 2012

One of the controversial avian flu studies published in full finally

After endless debates and controversies on whether two studies that demonstrated how bird flu, also known as avian H5N1 influenza, or avian flu, should be published, one of them has appeared in the latest issue of the journal Nature in its entirety. The two studies aimed for publication in journals Nature and Science show how the bird flu virus could become transmissible from mammal-to-mammal; as humans are mammals, the same would apply to humans.

4 May 2012

Viewpoints: Doctor-led frugality; George will on his son's life with Down syndrome; Facebook spurs organ donors

In case you missed it, a recommendation came out last month that physicians cut back on using 45 common tests and treatments. ... Most doctors will agree with the recommendations on the list. But the problem of overuse is less one of bad doctors although there are a few; the problem is more one of good doctors working in a bad system. ... But we have to start somewhere -; and this list is a good start. Now it needs to be extended.

4 May 2012

UCLA creates crowd-sourced online gaming system to detect malaria

Online crowd-sourcing - in which a task is presented to the public, who respond, for free, with various solutions and suggestions - has been used to evaluate potential consumer products, develop software algorithms and solve vexing research-and-development challenges. But diagnosing infectious diseases?

4 May 2012

GenVec receives NIAID’s Phase I SBIR grant to support RSV vaccine program

GenVec, Inc. announced today that it has received a Phase I Small Business Innovation and Research (SBIR) grant from the National Institute of Allergy and Infectious Diseases (NIAID) of the National Institutes of Health (NIH) to support the Company's Respiratory Syncytial Virus (RSV) vaccine program.

4 May 2012

Scientists identify first gene associated with congenital asplenia

Researchers at Weill Cornell Medical College and Rockefeller University have identified the first gene to be linked to a rare condition in which babies are born without a spleen, putting those children at risk of dying from infections they cannot defend themselves against. The gene, Nkx2.5, was shown to regulate genesis of the spleen during early development in mice.

4 May 2012

Event launches report on U.S. global health R&D

A post on the Global Health Technologies Coalition's (GHTC) "Breakthroughs" blog describes an event to launch a recent report from GHTC and Policy Cures on "data on U.S. investments over the past 10 years in global health research and development (R&D)."

3 May 2012