Infectious Diseases News and Research

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Human protein may offer novel target for blocking HIV infection

A research group supported by the National Institutes of Health (NIH) has uncovered a new route for attacking the human immunodeficiency virus (HIV) that may offer a way to circumvent problems with drug resistance. In findings published today in the online edition of the Proceedings of the National Academy of Sciences, the researchers report that they have blocked HIV infection in the test tube by inactivating a human protein expressed in key immune cells.

29 Apr 2008

U.S., British HIV/AIDS researchers pessimistic about prospects of vaccine, survey finds

Leading HIV/AIDS researchers in Britain and the U.S. are pessimistic about the prospects of developing an HIV vaccine following the recent failure of a Merck vaccine candidate, according to a survey conducted by London's Independent, the Independent reports (Connor/Green, Independent, 4/24).

26 Apr 2008

Doctors should consider alternatives to antibiotics for sinusitis

When suffering through a sinus infection, many people ask for an antibiotic to speed their recovery. However, a recent review of clinical trials found that while antibiotics can provide minor improvements in uncomplicated sinusitis cases, most patients recover without the drugs within two weeks.

24 Apr 2008

United Arab Emirates establishes committee to develop HIV/AIDS strategy

The United Arab Emirates has established a committee to develop a national HIV/AIDS control and prevention strategy, Nada Al Marzouqi, National AIDS Program manager at the Ministry of Health, said recently, the Khaleej Times reports.

23 Apr 2008

Red colobus monkeys in Uganda found to harbor antibodies to an unknown orthopoxvirus

Researchers report this month that red colobus monkeys in a park in western Uganda have been exposed to an unknown orthopoxvirus, a pathogen related to the viruses that cause smallpox, monkeypox and cowpox. Most of the monkeys screened harbor antibodies to a virus that is similar - but not identical - to known orthopoxviruses.

22 Apr 2008

NIAID tackles drug-resistant tuberculosis

Tuberculosis (TB) has long been one of the world’s great killers. Now, forms of drug-resistant TB--multidrug (MDR) and extensively drug-resistant (XDR)--are occurring at an ominous and accelerating rate. To help in the fight against drug-resistant TB, the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, has formulated an MDR and XDR TB research agenda.

22 Apr 2008

Monkey malaria - the next bird flu?

An expert at the NIH has highlighted the threat of an emergent highly virulent form of malaria, questioning whether the disease has made the jump from animal to man.

22 Apr 2008

Daily Star examines antiretroviral access in Bangladesh

Bangladesh's Daily Star on Friday examined how most people living with HIV/AIDS in the country do not have access to antiretroviral drugs. According to the Star, the country's Essential Drugs Company does not manufacture or provide antiretrovirals to Bangladesh's only infectious diseases hospital because of the drugs' high cost.

21 Apr 2008

Commitment to conducting more basic research in search for HIV/AIDS vaccine 'prudent,' editorial says

The cancellation last fall of a Merck HIV/AIDS vaccine trial was "branded as a 'catastrophe' by one scientist and as setting the race for a cure 'back to square one' by others," a Washington Post editorial says, adding, "The hyperbole is understandable, but some perspective is in order."

21 Apr 2008

HHS Secretary Leavitt meets with health officials in Vietnam to discuss health issues, including HIV/AIDS

HHS Secretary Mike Leavitt on Thursday met with health officials in Ho Chi Minh City, Vietnam, to discuss health issues, including HIV/AIDS, Thanhnien News reports.

21 Apr 2008

MaxCyte introduces large scale transfection technology - accelerates cell-based assay development

MaxCyte has announced the introduction of its ITF Inline Transfection System, a validated platform for preparative transfection, based on unique flow electroporation technology.

21 Apr 2008

BioAlliance Pharma announces preliminary results from U.S. phase III trial for Loramyc

BioAlliance Pharma SA today announced the preliminary positive results for its US pivotal Phase III clinical trial with Loramyc (miconazole Lauriad), Mucoadhesive Buccal Tablets (MBT) developed for the treatment of OroPharyngeal Candidiasis in immunocompromised population. This trial was conducted to support an NDA filing to market the product in the US.

21 Apr 2008

Raptor Pharmaceuticals initiates phase IIa clinical study for Convivia

Raptor Pharmaceuticals Corp. has announced that its clinical development subsidiary, Bennu Pharmaceuticals Inc. , has initiated the Company's first clinical-stage program after dosing the first cohort in a Phase IIa study of oral 4-methylpyrazole ("4-MP") in subjects with ALDH2 deficiency, or ethanol intolerance, as the initial development stage of its Convivia program.

21 Apr 2008

HIV/AIDS prevention strategies for Ukraine discussed at Canadian forum

HIV/AIDS experts from Ukraine and Canada attended a forum in Winnipeg, Canada, on Thursday to discuss the epidemic in the former Soviet state, the Winnipeg Free Press reports.

18 Apr 2008

Purdue's new vaccine under development may provide protection against highly pathogenic bird flu

A new vaccine under development may provide protection against highly pathogenic bird flu and its evolving forms, according to researchers at Purdue University and the Centers for Disease Control and Prevention who discovered the new preventative drug and have tested it in mice.

17 Apr 2008

Scientists create monoclonal antibody libraries against avian influenza

An international group of American and Turkish research scientists, led by Sea Lane Biotechnologies, has created the first comprehensive monoclonal antibody libraries against avian influenza (H5N1) using samples from survivors of the 2005/2006 "bird flu" outbreak in Turkey.

15 Apr 2008

New mucosal vaccine against anthrax effective in early tests

Early studies show that a new mucosal vaccine against anthrax has the potential to provide military personnel with more effective and efficient protection against a "popular" bioweapon, according to a study published in the journal Clinical and Vaccine Immunology (CVI).

13 Apr 2008

Doxycycline effective against filariasis in Southeast Asia

Doxycycline alone is more effective against the most common form of filariasis in Southeast Asia than the standard treatment, with significantly fewer side effects, according to a new study published in the May 1 issue of Clinical Infectious Diseases and currently available online.

10 Apr 2008

Manipulating the immune system like a parasite

One day it may be possible to mimic the tactics used by parasites to trick the body into accepting transplanted tissues or organs.

10 Apr 2008

Hepatitis B virus triggers cell 'suicide' in patients with chronic infection

Scientists from UCL (University College London) have identified a key difference between people who can fight the Hepatitis B virus (HBV) off successfully and those who fail to do so - that a group of cells important in controlling the disease are triggered to 'commit suicide' in patients who are chronically infected.

9 Apr 2008