Inflammation News and Research

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Health benefits of modified formulation of curcumin supplements

The health benefits of over-the-counter curcumin supplements might not get past your gut, but new research shows that a modified formulation of the spice releases its anti-inflammatory goodness throughout the body.

7 Nov 2014

Obeticholic acid improves liver health in people with nonalcoholic steatohepatitis

An experimental drug aimed at treating a common liver disease showed promising results and potential problems in a multicenter clinical trial funded by the National Institutes of Health. The FLINT study found that people with nonalcoholic steatohepatitis (NASH) who took obeticholic acid (OCA) had improved liver health during that period, including decreased inflammation and fat in the liver and decreased body weight versus people receiving a placebo. OCA was also associated with increases in itching and total cholesterol.

7 Nov 2014

Asthma patients using behavioral therapy can improve lung health over the long-term

Asthma patients taught to habitually resist the urge to take deep breaths when experiencing symptoms were rewarded with fewer symptoms and healthier lung function, according to a new study from Southern Methodist University, Dallas.

6 Nov 2014

UCLA study: Asthma harms more than just the lungs, may be more harmful than previously thought

Asthma may be more harmful than was previously thought, according to UCLA researchers who found that genetic damage is present in circulating, or peripheral, blood. Doctors previously thought that the genetic damage it caused was limited to the lungs.

5 Nov 2014

Study suggests possible link between body fat and risk of immunotherapy toxicity

Immunotherapy that can be effective against tumors in young, thin mice can be lethal to obese ones, a new study by UC Davis researchers has found.

4 Nov 2014

Study: Tonsil removal for children with sleep apnea decreases asthma severity

Surgical removal of the tonsils and adenoids in children suffering from sleep apnea is associated with decreased asthma severity, according to the first large study of the connection, published in the journal PLOS Medicine.

4 Nov 2014

Study reports IL-37's activity in the adaptive immune system

A University of Colorado Cancer Center study published in this month's Proceedings of the National Academy of Sciences describes the activity of a recently discovered communication molecule of the body's immune system, Interleukin 37 or IL-37. It has been known to limit inflammation and the current study reports its activity in the adaptive immune system: IL-37 inhibits the ability of the immune system to recognize and target new antigens.

4 Nov 2014

UC Davis researchers link increased body fat and lethal drug reactions in mice

Immunotherapy that can be effective against tumors in young, thin mice can be lethal to obese ones, a new study by UC Davis researchers has found. The findings, published online today in The Journal of Experimental Medicine, suggest a possible link between body fat and the risk of toxicity from some types of immunotherapy.

3 Nov 2014

Wimpy antibody prevents more serious self-inflicted forms of kidney disease, researchers say

An antibody abundant in mice and previously thought to offer poor assistance in fighting against infection may actually play a key role in keeping immune responses in check and preventing more serious self-inflicted forms of kidney disease, researchers say.

3 Nov 2014

Researchers find independent predictors of end stage renal disease in teens

Researchers at örebro University found that high blood pressure, being overweight, elevation of a blood marker indicating inflammation, or the presence of protein in the urine in otherwise healthy teenage males were all independent predictors of end stage renal disease (ESRD) in later in life.

31 Oct 2014

Data reveals sustained local control for early stage lung cancer patients who receive SBRT

Analysis of data from an institutional patient registry on stereotactic body radiotherapy (SBRT) indicates excellent long-term, local control, 79 percent of tumors, for medically inoperable, early stage lung cancer patients treated with SBRT from 2003 to 2012, according to research presented today at the 2014 Chicago Multidisciplinary Symposium in Thoracic Oncology.

31 Oct 2014

Study identifies new targets for developing novel treatment for alcohol dependence

Bacteria in the gastrointestinal tract fulfill many vital functions and are critical for digestion. Yet, these same bacteria can induce strong inflammatory responses by the immune system if they penetrate the gut and enter the bloodstream.

31 Oct 2014

New research shows link between perinatal exposure to BPA and risk of food intolerance in later life

If it seems like more people are allergic to, or intolerant of, more and different kinds of foods than ever before, there might be a reason why. A new research published in November 2014 issue of The FASEB Journal, scientists show, for the first time, that there is a link between perinatal exposure to Bisphenol A (BPA) at low doses and the risk to develop food intolerance in later life.

31 Oct 2014

Aging astrocytes lose ability to protect motor neurons, reveal Cedars-Sinai ALS researchers

Lou Gehrig's disease, also known as amyotrophic lateral sclerosis, or ALS, attacks muscle-controlling nerve cells – motor neurons – in the brain, brainstem and spinal cord, leading to progressive weakness and eventual paralysis of muscles throughout the body. Patients typically survive only three to five years after diagnosis.

31 Oct 2014

UMass Amherst epidemiologist investigates risk of early menopause

The estimated 10 percent of women in Western nations who enter menopause before age 45 have an elevated risk of cardiovascular disease, as well as lower fertility. Now epidemiologist Elizabeth Bertone-Johnson at the University of Massachusetts Amherst is conducting the first large study to investigate whether vitamin D deficiency, inflammatory factors, hormones and other factors are associated with risk of early menopause, funded by NIH.

29 Oct 2014

CHOP, Temple University to jointly investigate new methods for eradicating HIV

The Children's Hospital of Philadelphia and Temple University have received a joint $4.3 million, four-year grant from the National Institute of Mental Health to investigate new methods to eradicate HIV that lurks in brain cells despite conventional antiviral treatments.

28 Oct 2014

TxCell demonstrates therapeutic potential of Col-Treg for treatment of autoimmune uveitis

TxCell SA, a biotechnology company developing innovative, economically viable, personalized T cell immunotherapies using antigen specific regulatory T-cells (Ag-Tregs) for severe chronic inflammatory and autoimmune diseases, announces today that TxCell researchers have achieved positive results for Col-Treg, its second product candidate from its ASTrIA platform, in a model of autoimmune uveitis, a leading cause of blindness with very limited treatment options.

28 Oct 2014

Roskamp Institute Discovers New Target For Drugs To Treat Alzheimer's Disease

Scientists at the Roskamp Institute, a not-for-profit biomedical research facility specializing in Alzheimer's disease research, have isolated a key molecule that gives researchers a new drug target for the treatment of the progressive, irreversible neurological disorder.

28 Oct 2014

RPC1063 drug candidate has potential to improve treatment for ulcerative colitis patients

Positive new clinical data were released today on a drug candidate for ulcerative colitis that was first discovered and synthesized at The Scripps Research Institute.

28 Oct 2014

Research could pave way for more effective drugs to treat inflammation

Six Case Western Reserve scientists are part of an international team that has discovered two compounds that show promise in decreasing inflammation associated with diseases such as ulcerative colitis, arthritis and multiple sclerosis.

25 Oct 2014

Inflammation News and Research

Health benefits of modified formulation of curcumin supplements

Obeticholic acid improves liver health in people with nonalcoholic steatohepatitis

Asthma patients using behavioral therapy can improve lung health over the long-term

UCLA study: Asthma harms more than just the lungs, may be more harmful than previously thought

Study suggests possible link between body fat and risk of immunotherapy toxicity

Study: Tonsil removal for children with sleep apnea decreases asthma severity

Study reports IL-37's activity in the adaptive immune system

UC Davis researchers link increased body fat and lethal drug reactions in mice

Wimpy antibody prevents more serious self-inflicted forms of kidney disease, researchers say

Researchers find independent predictors of end stage renal disease in teens

Data reveals sustained local control for early stage lung cancer patients who receive SBRT

Study identifies new targets for developing novel treatment for alcohol dependence

New research shows link between perinatal exposure to BPA and risk of food intolerance in later life

Aging astrocytes lose ability to protect motor neurons, reveal Cedars-Sinai ALS researchers

UMass Amherst epidemiologist investigates risk of early menopause

CHOP, Temple University to jointly investigate new methods for eradicating HIV

TxCell demonstrates therapeutic potential of Col-Treg for treatment of autoimmune uveitis

Roskamp Institute Discovers New Target For Drugs To Treat Alzheimer's Disease

RPC1063 drug candidate has potential to improve treatment for ulcerative colitis patients

Research could pave way for more effective drugs to treat inflammation

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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