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Study suggests new targets for treating rare genetic disorder and cancer

The combined action of two enzymes, Srs2 and Exo1, prevents and repairs common genetic mutations in growing yeast cells, according to a new study led by scientists at NYU Langone Medical Center.

2 Jun 2014

Findings could lead to treatments for blood disorders associated with iron deficiencies and overloads

A UCLA research team has discovered a new hormone called erythroferrone, which regulates the iron supply needed for red blood-cell production.

2 Jun 2014

New software tool helps identify genetic mutations linked to increased risk for cancer

Researchers at The University of Texas MD Anderson Cancer Center and other institutions have applied a newly developed software tool to identify genetic mutations that contribute to a person's increased risk for developing common, complex diseases, such as cancer.

31 May 2014

CIRM grants $5.6 million to develop HIV/AIDS therapeutic using Sangamo's ZFN genome-editing technology

Sangamo BioSciences, Inc. announced that the California Institute for Regenerative Medicine (CIRM) has granted a $5.6 million Strategic Partnership Award to fund clinical studies at City of Hope to develop a potentially curative ZFP Therapeutic for HIV/AIDS based on the application of Sangamo's zinc finger nuclease (ZFN) genome-editing technology in hematopoietic stem/progenitor cells (HSPCs).

31 May 2014

Researchers develop virtual platform that measures level of addiction of smokers

In Mexico, 21.7 percent of the population smokes, which is associated with 95 percent of  lung cancer cases and the development of 29 more different conditions.

31 May 2014

Physicians and scientists to discuss health, fitness and well-being at ACSM Annual Meeting

The 61st ACSM Annual Meeting brings more than 6,000 physicians, scientists, educators, students and others to the Orange County Convention Center in Orlando, May 27-31.

30 May 2014

Blood gene expression profile identifies patients with elevated risk of cardiovascular death

A study of 338 patients with coronary artery disease has identified a gene expression profile associated with an elevated risk of cardiovascular death. Used with other indicators such as biochemical markers and family history, the profile - based on a simple blood test - may help identify patients who could benefit from personalized treatment and counseling designed to address risk factors.

30 May 2014

Reduced glomerular filtration rate is independent risk factor for renal and urothelial cancer

Researchers who investigated the level of kidney function and subsequent cancer risk in more than one million adults have found that reduced glomerular filtration rate (GFR) — a key measure of reduced kidney function and chronic kidney disease (CKD) — is an independent risk factor for renal and urothelial cancer but not other cancer types.

30 May 2014

Women with PCOS more likely to experience chronic low-grade inflammation during pregnancy

Women who have polycystic ovary syndrome - the most common hormone disorder in women of reproductive age - are more likely to experience chronic low-grade inflammation during pregnancy than counterparts who do not have the condition, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM).

30 May 2014

Critically ill patients receiving steroids in ICU are more likely to develop delirium

New Johns Hopkins research suggests that critically ill patients receiving steroids in a hospital’s intensive care unit (ICU) are significantly more likely to develop delirium. Results of their research, they say, suggest minimizing the use of steroids could reduce delirium in the ICU.

28 May 2014

Stem cells in outer blood vessel wall appear to involve in brain reaction following stroke

Two years ago, a new type of stem cell was discovered in the brain that has the capacity to form new cells.

28 May 2014

Study suggests proton therapy may be effective, less toxic treatment option for head and neck cancer

In a small study, researchers from The University of Texas MD Anderson Cancer Center found that 93 percent of head and neck cancer patients treated with multi-field optimization intensity modulated proton therapy (MFO-IMPT) were cancer-free 28 months after treatment.

28 May 2014

Patients receiving steroids in hospital's ICU more likely to develop delirium, says study

New Johns Hopkins research suggests that critically ill patients receiving steroids in a hospital's intensive care unit (ICU) are significantly more likely to develop delirium. Results of their research, they say, suggest minimizing the use of steroids could reduce delirium in the ICU.

28 May 2014

Researchers develop active agents that may improve healing of inflammatory illnesses

It is something like the police force of our body: the immune system. It disables intruding pathogens, it dismantles injured tissue and boosts wound healing. In this form of 'self-defense' inflammatory reactions play a decisive role.

27 May 2014

Peptide antibodies hit immune-response-stifling MDSCs without harming other vital cells

Scientists have found a way to target elusive cells that suppress immune response, depleting them with peptides that spare other important cells and shrink tumors in preclinical experiments, according to a paper published online by Nature Medicine.

26 May 2014

Experts discuss potential advantages of bioresorbable vascular scaffolds at EuroPCR 2014

At EuroPCR 2014 yesterday, experts discussed the development in evidence for bioresorbable vascular scaffolds, which represent an era of vascular restoration in interventional cardiology.

23 May 2014

Eliminating scar tissue, inflammation may make tumors more deadly, find researchers

New research represents a significant change in the understanding of how pancreatic cancer grows - and how it might be defeated.

23 May 2014

Pain receptors may hold key to treating obesity, diabetes and improving metabolic health

Blocking a pain receptor in mice not only extends their lifespan, it also gives them a more youthful metabolism, including an improved insulin response that allows them to deal better with high blood sugar.

23 May 2014

EMA grants Advanced Therapy Medicinal Product classification for TxCell's Col-Treg

TxCell SA, a biotechnology company developing innovative, personalized cell-based immunotherapies using antigen specific regulatory T-cells (Ag-Tregs) for severe chronic inflammatory and autoimmune diseases, announces today that Col-Treg, its second therapeutic candidate from its ASTrIA platform, has been granted Advanced Therapy Medicinal Product (ATMP) classification by the Committee for Advanced Therapies (CAT) of the European Medicines Agency.

22 May 2014

Effects of radiofrequency ablation and complete endoscopic resection are equal in dysplastic Barrett's esophagus

According to a new systematic review article, radiofrequency ablation and complete endoscopic resection are equally effective in the short-term treatment of dysplastic Barrett's esophagus, but adverse event rates are higher with complete endoscopic resection.

22 May 2014

Inflammation News and Research

Study suggests new targets for treating rare genetic disorder and cancer

Findings could lead to treatments for blood disorders associated with iron deficiencies and overloads

New software tool helps identify genetic mutations linked to increased risk for cancer

CIRM grants $5.6 million to develop HIV/AIDS therapeutic using Sangamo's ZFN genome-editing technology

Researchers develop virtual platform that measures level of addiction of smokers

Physicians and scientists to discuss health, fitness and well-being at ACSM Annual Meeting

Blood gene expression profile identifies patients with elevated risk of cardiovascular death

Reduced glomerular filtration rate is independent risk factor for renal and urothelial cancer

Women with PCOS more likely to experience chronic low-grade inflammation during pregnancy

Critically ill patients receiving steroids in ICU are more likely to develop delirium

Stem cells in outer blood vessel wall appear to involve in brain reaction following stroke

Study suggests proton therapy may be effective, less toxic treatment option for head and neck cancer

Patients receiving steroids in hospital's ICU more likely to develop delirium, says study

Researchers develop active agents that may improve healing of inflammatory illnesses

Peptide antibodies hit immune-response-stifling MDSCs without harming other vital cells

Experts discuss potential advantages of bioresorbable vascular scaffolds at EuroPCR 2014

Eliminating scar tissue, inflammation may make tumors more deadly, find researchers

Pain receptors may hold key to treating obesity, diabetes and improving metabolic health

EMA grants Advanced Therapy Medicinal Product classification for TxCell's Col-Treg

Effects of radiofrequency ablation and complete endoscopic resection are equal in dysplastic Barrett's esophagus

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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