Inflammation News and Research

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Musical memory organized at least partially independent of the hippocampus

Together with his team, Prof. Christoph Ploner, director of the Department of Neurology at the Virchow campus, examined a professional cellist who suffered from encephalitis caused by a herpes virus. As a result of the inflammation, the patient developed serious disturbances in memory. Both his memory for the past (retrograde amnesia), as well as the acquisition of new information (anterograde amnesia) were affected.

22 Aug 2012

CIRT to determine whether methotrexate can reduce heart attacks, strokes and CVD deaths

An international multi-site trial has launched to determine whether a common anti-inflammatory drug can reduce heart attacks, strokes, and deaths due to cardiovascular disease in people at high risk for them. This study is being supported by the National Heart, Lung, and Blood Institute (NHLBI), a part of the National Institutes of Health.

22 Aug 2012

GM-CSF depletion suppresses pain in people with arthritis-related conditions

The research relates to a family of molecules firstly discovered in Melbourne that applied to blood cell development. One of these, granulocyte macrophage colony-stimulating factor or GM-CSF, acts as a messenger between cells acting at a site of inflammation.

22 Aug 2012

HDL cholesterol benefits reduced with high C-reactive protein

The cardioprotective effects of high-density lipoprotein cholesterol are compromised in the presence of elevated high-sensitivity C-reactive protein, report researchers.

21 Aug 2012

Stem-cell therapy holds promise for postinjury arthritis prevention

A novel stem-cell treatment may hold the key to treating osteoarthritis triggered by joint injury, suggest results from an animal study.

21 Aug 2012

Berry wines may help people with diabetes decrease their blood sugar

In evaluating the bioactive compounds of Illinois blueberry and blackberry wines, University of Illinois scientists have found compounds that inhibit enzymes responsible for carbohydrate absorption and assimilation. And that could mean a tasty way to help people with diabetes decrease their blood sugar.

21 Aug 2012

Methyl-glyoxal could play a major role in abdominal obesity, insulin resistance and type 2 diabetes

Researchers at Mount Sinai School of Medicine have identified a common compound in the modern diet that could play a major role in the development of abdominal obesity, insulin resistance, and type 2 diabetes.

21 Aug 2012

New attack on arthritis pain

A research team from the University of Melbourne is working on a new therapy that can potentially control the pain caused by diseases such as rheumatoid arthritis and osteoarthritis.

21 Aug 2012

Live bacteria in more than 90% of middle ear effusions

Live bacteria are present in more than 90% of middle ear effusions, research shows.

20 Aug 2012

Injectable controlled-release capsules against gum disease

Scientists are trying to open a new front in the battle against gum disease, the leading cause of tooth loss in adults and sometimes termed the most serious oral health problem of the 21st century. They described another treatment approach for the condition in a report here today at the 244th National Meeting & Exposition of the American Chemical Society, the world's largest scientific society.

20 Aug 2012

Resveratrol might help improve mobility and prevent life-threatening falls among older people

In a stride toward better health in later life, scientists reported today that resveratrol, the so-called "miracle molecule" found in red wine, might help improve mobility and prevent life-threatening falls among older people.

20 Aug 2012

Diabetes Research Institute to receive JDRF-HCT grant for islet encapsulation study

JDRF, in collaboration with The Leona M. and Harry B. Helmsley Charitable Trust (HCT), announced today that it has finalized a grant in the area of islet cell encapsulation to Dr. Camillo Ricordi, M.D. and a team of investigators at the Diabetes Research Institute (DRI), based at the University of Miami (FL).

17 Aug 2012

Mepolizumab almost halves exacerbations in severe asthma patients

The largest study of patients with severe asthma to date, published in The Lancet special issue on respiratory medicine, shows that those treated with the monoclonal antibody mepolizumab experienced an almost 50% reduction in severe exacerbations, emergency room visits, and hospitalisations compared with patients given placebo.

17 Aug 2012

Nostrum, VCU sign license agreement to develop inhaled dapsone for respiratory diseases

Virginia Commonwealth University and Nostrum Pharmaceuticals, LLC, are pleased to announce the signing of a license agreement for the development of inhaled dapsone for the treatment of respiratory diseases.

17 Aug 2012

CDC recommends hepatitis C screening for all patients born from 1945-1965

Without other risk factors, all Americans born between 1945 and 1965 should have a one-time screening for the hepatitis C virus (HCV) according to new recommendations being published early online today in Annals of Internal Medicine, the flagship journal of the American College of Physicians. The Centers for Disease Control and Prevention (CDC) also recommends that all persons identified with HCV should receive a brief alcohol screening and intervention and be referred to appropriate care and treatment services for HCV and related conditions.

17 Aug 2012

T. gondii can cause inflammation in the brain

A parasite thought to be harmless and found in many people may actually be causing subtle changes in the brain, leading to suicide attempts.

17 Aug 2012

PKS-positive E. coli may encourage development of colon cancer

Scientists at the University of Liverpool have identified a type of E. coli bacteria that may encourage the development of colon cancer.

17 Aug 2012

Blood typifies coronary risk

Individuals with an A, B, or AB blood type have a significantly higher risk for coronary heart disease than those with an O blood type, say experts.

16 Aug 2012

People with no dementia symptoms and high protein levels more likely to avoid the disease

People who are free of dementia and have high levels of a protein that indicates the presence of inflammation have relatives who are more likely to avoid the disease as well, according to a new study published in the August 15, 2012, online issue of Neurology, the medical journal of the American Academy of Neurology.

16 Aug 2012

Tofacitinib drug shows promise against moderate-to-severe ulcerative colitis

An investigational drug currently under FDA review for the treatment of rheumatoid arthritis has now shown positive results in patients with moderate-to-severe ulcerative colitis, according to researchers at the University of California San Diego, School of Medicine.

16 Aug 2012