Inflammation News and Research

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Potential new ways to design vaccines, antibiotics

A University of Louisville scientist has determined for the first time how the bacterium that causes Legionnaires' disease manipulates our cells to generate the amino acids it needs to grow and cause infection and inflammation in the lungs.

18 Nov 2011

NewYork-Presbyterian/Columbia opens Center for Acute Respiratory Failure

NewYork-Presbyterian Hospital/Columbia University Medical Center has officially opened the Center for Acute Respiratory Failure, which offers, among other services, expertise in using lung bypass technology to help adult patients whose lungs are rapidly shutting down.

18 Nov 2011

Emory-Georgia Tech symposium to focus on health and human microbiome

The Seventh Annual Symposium on Predictive Health, to be held on Friday, Dec. 2, 2011, will focus on health and the human microbiome. The human microbiome consists of the microscopic organisms, such as bacteria, fungi and viruses, which reside throughout the body.

18 Nov 2011

Researchers identify protein that affects production of extracellular vesicles

Researchers at NYU Langone Medical Center have discovered a protein called TAT-5 that affects the production of extracellular vesicles, small sacs of membrane released from the surface of cells, capable of sending signals to other cells.

17 Nov 2011

Vitamin D and its good and bad effects on the heart

Vitamin D in excess may not be beneficial and may even harm the heart says a new study. Scientists have long known that low levels of the nutrient can hurt the heart, but new research shows that higher than normal levels can make it beat too fast and out of rhythm, a condition called atrial fibrillation. The study was presented at the annual meeting of the American Heart Association.

17 Nov 2011

ACR special issue focuses on assessing adult pain

Assessment of patient outcomes allows physicians and researchers to measure the success or failure of diagnostics and treatments that patients receive. One set of measurement tools focuses on assessing adult pain and is included in a special issue of Arthritis Care & Research, a journal of the American College of Rheumatology (ACR), providing physicians and researchers with a single resource of 250 patient outcomes measurements in rheumatology.

17 Nov 2011

Complications from preventable surgical-site infections leading to hospital readmissions after colon surgery

Nearly one-quarter of privately insured colon surgery patients are readmitted to the hospital within three months of discharge at a cost of roughly $9,000 per readmission, according to Johns Hopkins researchers, who've identified a major area for quality improvement and cost reduction in health care.

17 Nov 2011

Psoriasis may alter cholesterol composition and decrease HDL function

Collaborative research from Perelman School of Medicine at the University of Pennsylvania has shown that psoriasis patients have an increased risk of heart attack, stroke and cardiovascular death, especially if the psoriasis is moderate to severe. Now, Penn researchers have discovered the potential underlying mechanism by which the inflammatory skin disease impacts cardiovascular health.

17 Nov 2011

Probiotic before radiation therapy can protect intestine from damage

Scientists at Washington University School of Medicine in St. Louis have shown that taking a probiotic before radiation therapy can protect the intestine from damage — at least in mice.

17 Nov 2011

TNF inhibitors may minimally increase risk of serious infections

Biologic drugs have revolutionized treatment of autoimmune diseases during the past decade despite belief there is an increased risk for serious infections from using them. But new research from the University of Alabama at Birmingham Center for Education and Research on Therapeutics reveals that a class of biologics called tumor necrosis factor antagonists, or TNF inhibitors, may only minimally increase risk compared to more traditional therapies.

17 Nov 2011

Researchers identify hepcidin hormone as potential target for atherosclerosis

Researchers at Emory University School of Medicine have identified hepcidin, a hormone that regulates iron levels in the body, as a potential target for treating atherosclerosis.

17 Nov 2011

Severity of smoke-inhalation injury may play a role in overall pulmonary inflammatory response

A study of burn patients has found that those who suffered the most severe smoke inhalation also had more inflammation and spent more time on ventilators and in intensive care.

17 Nov 2011

CIHR honors University of Calgary scientist with prestigious award for medical research

University of Calgary researcher Paul Kubes, PhD, is the recipient of one of Canada's top awards for medical research. An internationally-recognized scientist specializing in visualizing the mammalian immune system, Kubes will accept the 2011 Canada's Health Researcher of the Year award from the Canadian Institutes of Health Research (CIHR) at a ceremony in Ottawa this evening.

17 Nov 2011

Mycophenolate mofetil superior to azathioprine for lupus nephritis

A new large, international study finds that the immunosuppressant drug mycophenolate mofetil is superior to azathioprine, an older immunosuppressant, as a maintenance therapy for lupus nephritis.

17 Nov 2011

Dipyrone may reduce brain damage after stroke

An older nonsteroidal anti-inflammatory drug (NSAID) called dipyrone may offer a new approach to reducing injury to brain tissue after a stroke, according to a study in the October issue of Neurosurgery, official journal of the Congress of Neurological Surgeons.

17 Nov 2011

Leading alcohol researchers to discuss latest genetic findings at Loyola meeting

Leading alcohol researchers from the United States and Canada will discuss their latest findings at an all-day meeting Nov. 18 at Loyola University Chicago Stritch School of Medicine.

16 Nov 2011

Coronary calcium scoring can determine risk of cardiac events

If your doctor says you have a negative stress test, or that your cholesterol or blood pressure are normal, how assured can you be that you're not likely to have a heart attack in the next seven to 10 years?

16 Nov 2011

Sex during adolescence can have negative effects on body and mood well into adulthood

A new study suggests that sex during adolescence can have lasting negative effects on the body and mood well into adulthood, most likely because the activity occurs when the nervous system is still developing.

16 Nov 2011

Scientists discover definitive role for brain in regulating loss of muscle mass

Patients with cancer, heart disease and other chronic illness struggle not only with complications inherent to their disease, they also experience an involuntary loss of weight and muscle mass triggered by the body's natural response to infection and inflammation. Increasing nutrition intake does not mitigate the process and there is no treatment.

16 Nov 2011

Two proteins conspire to promote amyotrophic lateral sclerosis

Two proteins conspire to promote a lethal neurological disease, according to a study published online this week in the Journal of Experimental Medicine.

15 Nov 2011