Inflammation News and Research

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Discovery of fundamental mechanism within cells that link obesity and type 2 diabetes

Researchers from the Harvard School of Public Health have discovered what they believe is the fundamental mechanism within cells that links two fast-rising public health threats: obesity and Type 2 diabetes.

18 Oct 2004

Study underscores the relative safety of infliximab, when used properly

Rheumatoid arthritis patients receiving the recommended starting dose (3mg/kg) of infliximab (REMICADE®) have no more serious rate of infections than do patients taking methotrexate alone

18 Oct 2004

COX-2 agents have influenced the way physicians prescribe rheumatology medication

COX-2 agents, with their perceived reduction in side effects, have contributed substantially to a dramatic increase in NSAIDs (non-steroidal anti-inflammatory drugs) prescription utilization and influenced the way physicians prescribe rheumatology medication

18 Oct 2004

Pneumococcal vaccinations help protect patients with rheumatoid arthritis against serious pneumococcal infections of the lungs, brain, blood, and ears

Rheumatoid arthritis patients have an approximately two-fold increased morbidity and mortality in infections compared to a population without the disease.

18 Oct 2004

Location of body fat on older women can indicate the likelihood of heart disease

The location of body fat on older women can indicate the likelihood of heart disease, according to a new study published in The Journal of Clinical Endocrinology & Metabolism.

16 Oct 2004

Low dose aspirin dosages trigger the body to generate its own anti-inflammatory compounds

Researchers at Brigham and Women’s Hospital (BWH) and colleagues have demonstrated for the first time in humans in a randomized clinical trial that low-dose aspirin - dosages equivalent to one baby aspirin (81 mg) - trigger the body to generate its own anti-inflammatory compounds that help fight unwanted inflammation.

13 Oct 2004

University of Cambridge executes exclusive patent licences and collaborative research and development agreement with Gene Networks International

The University of Cambridge has entered into two licence agreements with Gene Networks International (GNI), granting exclusive rights to Cambridge's intellectual property related to angiogenesis (the growth of new blood vessels) and inflammation that may have implications in the identification of new drug targets for a range of diseases.

13 Oct 2004

Herbal, nutritional supplements linked to side effects ranging from dry eye to retinal hemorrhages and transient visual loss

An estimated 42 percent of Americans use herbal medicines or nutritional supplements. Many people taking these products and their physicians are unaware of the adverse reactions they can cause.

13 Oct 2004

Researchers have discovered an effective new way to treat giant cell arteritis

Mayo Clinic researchers have discovered an effective new way to treat giant cell arteritis (GCA), a debilitating cause of headaches, fatigue, muscle pain and even blindness. The findings of this research will be presented at the American College of Rheumatology Annual Scientific Meeting.

13 Oct 2004

Research in children has shown that blood loss after heart surgery can be minimized if fresh whole blood is used for transfusions

A standard medical practice at some of the nation's largest children's hospitals – using whole, recently donated blood for certain infant open heart surgeries – may do more harm than good.

13 Oct 2004

Transparent gel could soon become the first and best choice for sealing corneal incisions

The substance, known as a hydrogel, promises to be a useful tool in the kit used for the most common of ophthalmic surgeries: cataract removal. Currently, 11 million such surgeries are performed worldwide annually, a figure expected to increase as the world's population grows older.

12 Oct 2004

Biomedical engineers receive $11.5 million to study how white blood cells navigate

We all know the power of touch: A whack on the skull – or a hug – can convey more information than other forms of communication ever can. It turns out the same is true inside our bodies

12 Oct 2004

Global effort to relieve chronic pain

The World Health Organization (WHO) co-sponsors the first Global Day Against Pain, which seeks to draw global attention to the urgent need for better pain relief for sufferers from diseases such as cancer and AIDS.

11 Oct 2004

Signaling pathway could be a valuable target for future drug therapies against systemic lupus erythematosus

Medical investigators at the Hospital for Special Surgery have identified an important new signaling pathway they believe could be a valuable target for scientists to aim at with future drug therapies that might one day reverse diseases such as systemic lupus erythematosus, according to a recent article published in “Nature Immunology.”

11 Oct 2004

Exposure to tobacco smoke and pollutants increases childhood risk of asthma

Children prenatally exposed to pollutants, such as motor vehicle exhaust, and postnatally exposed to environmental tobacco smoke (ETS) may be more likely to suffer from asthma and related symptoms early in life.

11 Oct 2004

Atheromatosis, which lies behind heart attacks, stroke, and other cardiovascular problems, has a major impact on public health

These two diseases are completely different from each other, but they do have one common denominator: inflammation. Researchers at Lund University in Sweden can now show that it might also be possible to treat them with the same drug.

10 Oct 2004

Progestin in hormone therapy could dramatically affect heart attack severity

“One type of hormone therapy limited heart muscle damage to only 5 percent while another resulted in permanent damage to 35 percent of muscle,” said J. Koudy Williams, Ph.D., lead investigator, from Wake Forest Baptist. “If we can learn more about this mechanism we might be able to identify better hormone therapies for postmenopausal women.”

10 Oct 2004

Immune responses to airborne fungi could cause the stuffy noses and airway inflammation among sufferers of chronic rhinosinusitis

A team led by Mayo Clinic researchers has determined that over-reactive immune responses to airborne fungi could cause the stuffy noses and airway inflammation among sufferers of chronic rhinosinusitis.

10 Oct 2004

Researchers have found a starting point to establishing the genetic basis for sinus disease

In a three-year analysis of more than 10,500 genes, one-third of the human genome, researchers at Johns Hopkins have found a starting point to establishing the genetic basis for sinus disease and the growth of nasal polyps, illnesses not well understood despite their prevalence.

8 Oct 2004

Research shows C. botulinum uses SONO to detect nitric oxide

A deadly bacterium's defense against a mortal molecular enemy illuminates the origins and structure of a vital protein involved in human cell signaling, University of Texas Medical School scientists report in Science Express.

8 Oct 2004

Inflammation News and Research

Discovery of fundamental mechanism within cells that link obesity and type 2 diabetes

Study underscores the relative safety of infliximab, when used properly

COX-2 agents have influenced the way physicians prescribe rheumatology medication

Pneumococcal vaccinations help protect patients with rheumatoid arthritis against serious pneumococcal infections of the lungs, brain, blood, and ears

Location of body fat on older women can indicate the likelihood of heart disease

Low dose aspirin dosages trigger the body to generate its own anti-inflammatory compounds

University of Cambridge executes exclusive patent licences and collaborative research and development agreement with Gene Networks International

Herbal, nutritional supplements linked to side effects ranging from dry eye to retinal hemorrhages and transient visual loss

Researchers have discovered an effective new way to treat giant cell arteritis

Research in children has shown that blood loss after heart surgery can be minimized if fresh whole blood is used for transfusions

Transparent gel could soon become the first and best choice for sealing corneal incisions

Biomedical engineers receive $11.5 million to study how white blood cells navigate

Global effort to relieve chronic pain

Signaling pathway could be a valuable target for future drug therapies against systemic lupus erythematosus

Exposure to tobacco smoke and pollutants increases childhood risk of asthma

Atheromatosis, which lies behind heart attacks, stroke, and other cardiovascular problems, has a major impact on public health

Progestin in hormone therapy could dramatically affect heart attack severity

Immune responses to airborne fungi could cause the stuffy noses and airway inflammation among sufferers of chronic rhinosinusitis

Researchers have found a starting point to establishing the genetic basis for sinus disease

Research shows C. botulinum uses SONO to detect nitric oxide

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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