Inherit News and Research

RSS

Selfish mutant mtDNA exploits cellular defenses to cause many diseases

Mitochondrial disorders are a chameleon-like set of diseases that take many different forms and vary widely from individual to individual.

12 Jul 2016

New lung-targeted gene therapy shows promise in improving treatment for emphysema

Researchers have developed a new strategy using lung-targeted gene therapy that may lead to improved treatments for inherited diseases including emphysema.

6 Jul 2016

Scientists identify genetic mutations linked to synchronous colorectal cancers

Researchers have identified genetic mutations affecting the immune system which may lead to the development of more than one bowel tumour at the same time. Understanding how these cancers develop could improve targeting of therapies, according to the study published in Nature Communications.

5 Jul 2016

Study could offer new ways to enhance cancer immunotherapy

When an immune T cell divides into two daughter cells, the activity of an enzyme called mTORC1, which controls protein production, splits unevenly between the progeny, producing two cells with different properties.

4 Jul 2016

New study sheds light on impact of unknown genetic mutations in cystic fibrosis patients

When it comes to cystic fibrosis (CF), more than 2,000 different genetic mutations have been reported. However, only 200 of them have been categorized - leaving a genetic soup of 1,800 others for scientists and genetic counselors to figure out.

8 Jun 2016

Study shows birth defects in immune system function may contribute to malnutrition

Malnourished children are most likely to die from common infections, not starvation alone, and immune disorder may be part of the cause, according to a review led by Queen Mary University of London.

27 May 2016

Researchers partially restore lost function of isolated cystic fibrosis lung cells

In experiments with isolated cystic fibrosis lung cells, University of Alabama at Birmingham researchers and colleagues from two other institutions have partially restored the lost function of those cells.

26 May 2016

Researchers identify new molecular targets for recovering motor function in men afflicted with SBMA

Michigan State University researchers used an old-fashioned neurobiology technique to explore new avenues for treatments to reverse a late-onset neurodegenerative disease that robs men of the capacity to walk, run, chew and swallow.

9 May 2016

Key protein involved in mitosis helps prevent abnormal distribution of chromosomes

A tension-sensitive "fail safe" protein helps make sure that when our cells divide the two resulting cells inherit the normal number of chromosomes, researchers from the University of Washington and the Fred Hutchinson Cancer Research Center report today, May 5, in the journal Cell.

6 May 2016

Existing UK law fails to protect best interests of children born to surrogates, say experts

In an article in the Medical Law Review, Dr Kirsty Horsey, of the University of Kent, describes cases that show current surrogacy law in the UK is 'fraying at the edges'.

5 May 2016

Novel spoken-language intervention could benefit children, adolescents with developmental disabilities

Sean Sawicki, who has fragile X syndrome, can be hard to understand and doesn't always have the attention span to carry on a sustained conversation. But a novel intervention developed by UC Davis MIND Institute researchers seems to be making a difference.

28 Apr 2016

Novel method could help analyze GWAS results for sporadic diseases

Using a novel method, Whitehead Institute researchers have determined how a non-coding mutation identified in genome-wide association studies can contribute to sporadic Parkinson's disease (PD). The approach could be used to analyze GWAS results for other sporadic diseases with genetic causes, such as multiple sclerosis, diabetes, and cancer.

21 Apr 2016

Using Proteomics to Understand Alzheimer’s: An Interview with Dr Renã Robinson

In our bioanalytical mass spectrometry lab we use proteomics techniques to try to understand more about Alzheimer's disease. The primary thrust of our research is that we're interested in understanding the changes that take place outside of the brain and how those correlate with what's taking place inside the brain

From Pittcon 21 Apr 2016

Study: British adults agree to donate heart, kidney and lungs, but not eyes for transplant

Despite a shortage of corneas for transplant purposes, new research reveals that eyes are the one body part we are least likely to donate.

19 Apr 2016

Study shows how homosexuality exists among humans throughout history

Around half of all heterosexual men and women potentially carry so-called homosexuality genes that are passed on from one generation to the next. This has helped homosexuality to be present among humans throughout history and in all cultures, even though homosexual men normally do not have many descendants who can directly inherit their genes.

13 Apr 2016

Commonly used fungicides could cause gene expression changes in brain cells

Scientists at the UNC School of Medicine have found a class of commonly used fungicides that produce gene expression changes similar to those in people with autism and neurodegenerative conditions, including Alzheimer's disease and Huntington's disease.

31 Mar 2016

DNA changes may affect a person's lifespan

Scientists have identified DNA changes that can cut a person's lifespan by up to three years.

31 Mar 2016

Qlucore’s Omics Explorer enables researchers to study genetic influences behind Li-Fraumeni Syndrome

While childhood cancer is rare (adult malignancies after 20 years are 20-30 times more common in general) it remains a major cause of death by disease in children. 15,700 children are diagnosed with cancer each year in the USA.

31 Mar 2016

New TAU study pinpoints precise mechanism that regulates inheritance of epigenetic responses

According to epigenetics -- the study of inheritable changes in gene expression not directly coded in our DNA -- our life experiences may be passed on to our children and our children's children. Studies on survivors of traumatic events have suggested that exposure to stress may indeed have lasting effects on subsequent generations. But how exactly are these genetic "memories" passed on?

29 Mar 2016

Research: X and Y DNA swapping may occur more often than previously thought

It turns out that the rigid "line in the sand" over which the human sex chromosomes---the Y and X--- go to avoid crossing over is a bit blurrier than previously thought. Contrary to the current scientific consensus, Arizona State University assistant professor Melissa Wilson Sayres has led a research team that has shown that X and Y DNA swapping may occur much more often.

24 Mar 2016

Inherit News and Research

Selfish mutant mtDNA exploits cellular defenses to cause many diseases

New lung-targeted gene therapy shows promise in improving treatment for emphysema

Scientists identify genetic mutations linked to synchronous colorectal cancers

Study could offer new ways to enhance cancer immunotherapy

New study sheds light on impact of unknown genetic mutations in cystic fibrosis patients

Study shows birth defects in immune system function may contribute to malnutrition

Researchers partially restore lost function of isolated cystic fibrosis lung cells

Researchers identify new molecular targets for recovering motor function in men afflicted with SBMA

Key protein involved in mitosis helps prevent abnormal distribution of chromosomes

Existing UK law fails to protect best interests of children born to surrogates, say experts

Novel spoken-language intervention could benefit children, adolescents with developmental disabilities

Novel method could help analyze GWAS results for sporadic diseases

Using Proteomics to Understand Alzheimer’s: An Interview with Dr Renã Robinson

Study: British adults agree to donate heart, kidney and lungs, but not eyes for transplant

Study shows how homosexuality exists among humans throughout history

Commonly used fungicides could cause gene expression changes in brain cells

DNA changes may affect a person's lifespan

Qlucore’s Omics Explorer enables researchers to study genetic influences behind Li-Fraumeni Syndrome

New TAU study pinpoints precise mechanism that regulates inheritance of epigenetic responses

Research: X and Y DNA swapping may occur more often than previously thought

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

Latest News