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Study reveals accelerated progression of Alzheimer's in people with Down syndrome

Nearly all adults with Down syndrome will develop evidence of Alzheimer's disease by late middle age.

16 Apr 2024

Research unveils a cellular shield against harmful effects of UV-induced RNA damage

UV radiation in the sunlight causes sunburn and increases the risk of skin cancer by damaging our DNA but also our RNA.

18 Mar 2024

Maternal obesity linked to liver cancer risk in offspring

Obesity, which could reach 50% of the population in certain developed countries by 2030, is a major public health concern.

12 Mar 2024

New insights into the evolution of genomic imprinting

Some of our genes can be expressed or silenced depending on whether we inherited them from our mother or our father.

6 Mar 2024

Study reveals novel mechanism for longevity of oocytes

Oocytes are immature egg cells that develop in almost all female mammals before birth. The propagation of future generations depends on this finite reserve of cells surviving for many years without incurring damage.

20 Feb 2024

What are your concerns about the possibility of having children? Survey of parenthood intentions for 16–18-year-old students

Researchers surveyed 16- to 18-year-old undergraduates about their plans to become parents in England.

15 Feb 2024

Parental traits offer new clues to predicting neurodevelopmental disorders in children

Predicting the trajectory of neurodevelopmental and psychiatric disorders like autism or schizophrenia is difficult because they can be influenced by many different genetic and environmental factors.

8 Feb 2024

APOE4 genetic risk factors for Alzheimer's disease associated with increased risk of subclinical atherosclerosis

Scientists at the Centro Nacional de Investigaciones Cardiovasculares in Madrid have found that one of the most potent genetic risk factors for Alzheimer disease, apolipoprotein E4 (APOE4), is also associated with an increased risk of developing subclinical atherosclerosis in middle age.

23 Jan 2024

Childless by choice becomes new normal for young UK adults, survey finds

A comprehensive new survey reveals the changing face of UK families amid recent economic, social, and political turmoil.

18 Jan 2024

Research uncovers cells-of-origin for breast cancer in BRCA2 mutation carriers

Australian scientists have pinpointed likely 'cells-of-origin', the source cells that can grow into breast cancer, in women carrying a faulty BRCA2 gene who are at high risk of developing the disease.

16 Jan 2024

Epigenetic changes can contribute to the development of type 2 diabetes

Do epigenetic changes cause type 2 diabetes, or do the changes occur only after a person has become ill? A new study by researchers at Lund University provides increased support for the idea that epigenetic changes can cause type 2 diabetes.

13 Dec 2023

ANU research uncovers protein's role in autoimmune disease and cancer

A protein in the immune system programmed to protect the body from fungal infections is also responsible for exacerbating the severity of certain autoimmune diseases such as irritable bowel disease (IBS), type 1 diabetes, eczema and other chronic disorders, new research from The Australian National University (ANU) has found.

6 Dec 2023

Obesity linked to prostate cancer risk: New study uncovers inherited dangers from fathers

Obesity contributes to prostate cancer risk and can be inherited from obese fathers, as shown in a review of over 280 studies examining obesity's impact on carcinogenesis and heritability.

23 Nov 2023

Facing financial ruin as costs soar for elder care

Margaret Newcomb, 69, a retired French teacher, is desperately trying to protect her retirement savings by caring for her 82-year-old husband, who has severe dementia, at home in Seattle.

14 Nov 2023

What's really behind the male infertility crisis? New study seeks answers

This comprehensive study in Nature Reviews Urology tackles critical questions in male infertility, from its diagnosis and treatment to its impact on overall health. The review calls for a deeper understanding of male reproductive issues, better diagnostic methods, and improved public and medical awareness of the topic.

15 Oct 2023

Disinfectants used in food production may exacerbate antibiotic resistance

Yes, say researchers - who suspect that disinfectants used in food production may in fact be exacerbating a global public health problem.

5 Oct 2023

Study shows consanguinity may raise risk of type 2 diabetes and other common diseases

A new study finds that consanguinity – unions between close relatives – may increase the risk of common diseases such as type 2 diabetes and post-traumatic stress disorder (PTSD).

30 Sep 2023

Unions between close relatives may increase the risk of common diseases, study finds

A new study finds that consanguinity – unions between close relatives - may increase the risk of common diseases such as type 2 diabetes and post-traumatic stress disorder (PTSD).

26 Sep 2023

AlphaMissense revolutionizes genetic mutation analysis for disease prediction

AlphaMissense, an adaptation of AlphaFold, offers a highly accurate model for predicting the pathogenicity of human proteome-wide missense variants at the single amino acid level. The model outperforms existing methods, providing valuable insights for diagnosing rare diseases and developing targeted therapies.

20 Sep 2023

Researchers find new genes that contribute to hypoplastic left heart syndrome

By identifying genes in patients and testing their effects in fruit flies, researchers from Sanford Burnham Prebys have found new genes that contribute to hypoplastic left heart syndrome (HLHS), a rare, life-threatening heart disease that occurs in infants.

17 Jul 2023