Insulin Resistance News and Research

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Insulin Resistance is a condition in which the body does not respond to insulin properly. This is most common in Type II diabetes or associated with obesity, ketoacidosis, infection, and certain rare conditions. Diminished effectiveness of insulin in lowering blood glucose levels requiring 200 units or more of insulin per day to prevent hyperglycemia or ketosis.

Resveratrol helps prevent metabolic syndrome in offspring

Researchers in the Faculty of Medicine & Dentistry at the University of Alberta have discovered that resveratrol, a powerful antioxidant found in common foods, prevents a syndrome in some offspring that could lead to later health issues such as diabetes.

3 Sep 2011

Aerobic exercise best for belly fat reduction: Study

A new study has shown that the best type of exercise to burn unhealthy belly fat is aerobic exercise. The results showed that people who did aerobics for eight months lost about 2.5 square inches of belly fat, as measured on a CT scan. That's about 1.5 times as much as people who did a combination of aerobic exercise and weight lifting, and about 20 times as much as those who only lifted weights.

31 Aug 2011

Low-glycemic foods, high protein intake reduce body weight and fat mass

A new study out of Madrid, Spain shows that low-glycemic foods, and moderately high-protein intake has been shown to reduce body weight and fat mass.

29 Aug 2011

Obesity may predipose healthy young children to Type 2 diabetes, confirms study

Research led by Dr. Melinda Sothern, Professor of Public Health and Jim Finks Endowed Chair in Health Promotion at LSU Health Sciences Center New Orleans, has found that obese 7-9-year-old children had nearly three times the liver fat and almost double the belly fat of their nonobese counterparts and that insulin resistance was more than double and insulin sensitivity less than half respectively.

26 Aug 2011

Study: Aerobic training effectively reduces belly fat

Aerobic exercise is your best bet when it comes to losing that dreaded belly fat, a new study finds.

26 Aug 2011

Study finds biological indicators that help explain why obese people develop chronic diseases

UC Davis Health System researchers have discovered biological indicators that help explain why some obese people develop chronic diseases such as diabetes and heart disease, and others do not.

25 Aug 2011

MDA announces $13.7M in grants to 40 new muscular dystrophy research initiatives

The Muscular Dystrophy Association today announced funding, totaling $13.7 million, for 40 new research initiatives targeting nearly two dozen progressive neuromuscular diseases.

24 Aug 2011

Researchers show that Sirt3 enzyme decreases in skeletal muscle of diabetes patients

Researchers at the Joslin Diabetes Center have shown that an enzyme found in the mitochondria of cells is decreased in the skeletal muscle of those with diabetes, a finding that could lead to the development of drugs to boost the activity of this enzyme in an effort to fight the disease.

23 Aug 2011

Waist circumference does not effectively predict children with increased risk of diabetes

Waist circumference, a measure of belly fat, is not a better predictor than body mass index for identifying children with an increased risk of developing type 2 diabetes, according to a study by University of Michigan researchers.

20 Aug 2011

BTI completes SUGARDOWN human clinical study on blood sugar management

Boston Therapeutics, Inc. (BTI), a public company registered with the SEC and a developer of diabetes therapeutics, announced today the completion of a trial in healthy volunteers performed at the University of Sydney on SUGARDOWN, a dietary supplement designed to reduce post-meal elevation of blood glucose.

18 Aug 2011

New pathway for type 2 diabetes

Newly diagnosed type 2 diabetics tend to have one thing in common: obesity. Exactly how diet and obesity trigger diabetes has long been the subject of intense scientific research.

16 Aug 2011

Fat interferes with body's sugar sensors to trigger type 2 diabetes

Researchers from the United States have identified how a high-fat diet can trigger type 2 diabetes, in experiments on mice and human tissue. They reveal in their study published in the journal Nature Medicine that fat interferes with the body's sugar sensors. The authors add that deeper understanding of the processes involved could help them develop a cure.

15 Aug 2011

CPAP withdrawal leads to return of obstructive sleep apnea

The benefits of continuous positive airway pressure machines (CPAP) for patients with obstructive sleep apnea (OSA) are quickly reversed when the therapy is withdrawn, according to Swiss research.

12 Aug 2011

Negative physiological changes may raise risk of type 2 diabetes

According to the Centers for Disease Control and Prevention, 25 percent of Americans have inactive lifestyles and 75 percent do not meet the weekly exercise recommendations to maintain good health.

3 Aug 2011

UCSD researchers examine association of energy balance, breast cancer

A team of researchers from the University of California, San Diego School of Medicine and UC San Diego Moores Cancer Center will be participating in a cooperative agreement initiative, funded by the National Cancer Institute of the National Institutes of Health, with four other major cancer centers.

30 Jul 2011

AACE declares obesity as a disease state

The American Association of Clinical Endocrinologists has declared that there is significant clinical evidence to declare obesity as a disease state. The decision was made in a unanimous vote of the AACE Board of Directors at their quarterly meeting, July 23, in Dallas, TX.

30 Jul 2011

Muscle mass may influence risk for diabetes: Study

According to a new study greater muscle mass may reduce the odds of developing diabetes. There have been studies that show having less body fat reduces diabetes risk and that exercise can help too, but the new study by UCLA scientists suggests a link between higher muscle mass and a lower risk of diabetes.

29 Jul 2011

Relative muscle mass inversely linked with insulin resistance and pre-diabetes

A recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM) found that the greater an individual's total muscle mass, the lower the person's risk of having insulin resistance, the major precursor of type 2 diabetes.

28 Jul 2011

New study shows high prevalence of gout in the U.S.

A new study shows the prevalence of gout in the U.S. has risen over the last twenty years and now affects 8.3 million (4%) Americans.

28 Jul 2011

Takeda resubmits alogliptin and fixed-dose combination therapy NDA to FDA

Takeda Pharmaceutical Company Limited announced today that Takeda Global Research & Development Center, Inc., resubmitted two New Drug Applications to the United States Food and Drug Administration for alogliptin and the fixed-dose combination therapy alogliptin/pioglitazone, which combines alogliptin with pioglitazone in a single tablet.

26 Jul 2011