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Scientists uncover two Crohn’s disease subtypes using lab-grown intestines, offering hope for personalized therapies

Researchers used stem-cell derived organoids from Crohn's disease patients to identify two molecular subtypes, paving the way for personalized treatments targeting specific disease characteristics.

2 Oct 2024

Inflammatory proteins linked to higher risk of endometrial cancer

Study identifies key inflammatory and immune response proteins linked to endometrial cancer risk through both observational and Mendelian Randomization analyses, revealing the roles of IL-6 and HSD11B1.

1 Oct 2024

Iron retention in skin linked to psoriasis: Could hepcidin be the missing piece in treatment?

This study reveals hepcidin's significant role in psoriasis, linking iron retention to inflammation and keratinocyte growth, suggesting new therapeutic targets.

1 Oct 2024

Researchers identify a protein that recharges T cells for long-lasting cancer remission

Research shows Fc–IL-4 revitalizes exhausted CD8+ T cells, boosting antitumor responses and highlighting the potential of combining type 1 and type 2 immunity.

30 Sep 2024

Diet and gut dysbiosis linked to rheumatoid arthritis

Review highlights how gut dysbiosis and dietary factors are linked to rheumatoid arthritis, influencing disease progression and inflammation. Researchers explore how specific diets may help modulate the gut microbiome to improve symptoms.

29 Sep 2024

Understanding the role of TIPS in improving renal function amid cirrhosis

Cirrhosis is one of the leading causes of mortality from non-communicable diseases, with complications arising as liver function deteriorates.

26 Sep 2024

Researchers gain new understanding of how immune cells respond to heat during fever

The study reveals that moderate fever enhances CD4 T cell activity while reducing regulatory T cell suppression, highlighting temperature's immune effects.

25 Sep 2024

A faster, cheaper method to detect immune autoantibodies in whole blood

Researchers developed a quick and affordable whole-blood assay to detect autoantibodies against type I IFNs, enabling rapid diagnostics for immune disorders. This new method has potential clinical impact by addressing key limitations of current tests.

25 Sep 2024

Microbial biomarkers identified in lupus and IBD offer pathways for targeted therapies

Research connects gut microbiota to lupus and IBD, uncovering microbial markers and pathways that could inform targeted therapies for autoimmune disorders.

24 Sep 2024

Brazil nuts reduce inflammation and improve gut health in women on restricted diets

Brazil nut consumption in an energy-restricted diet significantly reduced inflammation and improved intestinal permeability in overweight/obese women, likely due to selenium’s anti-inflammatory properties.

23 Sep 2024

Blood microRNAs can predict conversion from mild cognitive impairment to dementia due to Alzheimer’s disease

This study identifies serum miRNA signatures as promising biomarkers for Alzheimer's, enhancing prediction of MCI conversion to AD with clinical relevance.

23 Sep 2024

Yoyo dieting alters gut health, driving weight regain and inflammation

Researchers from Deakin University reveal how yoyo dieting disrupts gut health, leading to weight regain and obesity-related complications. The study highlights the roles of gut microbiota, hormones, and inflammation in the weight cycling process.

23 Sep 2024

Dietary antigens reduce small intestine cancer by boosting immune T-cells

Study shows that dietary antigens can suppress small intestine carcinogenesis by activating T-cells through Peyer's patches. Adding bovine serum albumin (BSA) or ovalbumin (OVA) to antigen-free diets restored immune function and reduced tumor growth in mice.

22 Sep 2024

Interleukin News and Research

Scientists uncover two Crohn’s disease subtypes using lab-grown intestines, offering hope for personalized therapies

Inflammatory proteins linked to higher risk of endometrial cancer

Iron retention in skin linked to psoriasis: Could hepcidin be the missing piece in treatment?

Researchers identify a protein that recharges T cells for long-lasting cancer remission

Diet and gut dysbiosis linked to rheumatoid arthritis

Understanding the role of TIPS in improving renal function amid cirrhosis

Researchers gain new understanding of how immune cells respond to heat during fever

A faster, cheaper method to detect immune autoantibodies in whole blood

Microbial biomarkers identified in lupus and IBD offer pathways for targeted therapies

Brazil nuts reduce inflammation and improve gut health in women on restricted diets

Blood microRNAs can predict conversion from mild cognitive impairment to dementia due to Alzheimer’s disease

Yoyo dieting alters gut health, driving weight regain and inflammation

Dietary antigens reduce small intestine cancer by boosting immune T-cells

Childhood adversity linked to elevated health risks, differing by sex and stress

Cardiovascular disease pathways associated with psoriasis, but not other immune-mediated diseases

Blackcurrant supplements show promise in preventing bone density loss in post-menopausal women

Microbial-immune interactions in severe asthma: Insights into pathogen dominance and treatment approaches

Salt can boost antitumor responses of T cells

New discovery offers hope for overcoming CAR-T cell therapy resistance

New research aims to target IL-6 for treating diabetic retinopathy

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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