Interleukin 3 News and Research

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Stand Up to Cancer supports potential approach to more efficiently target pancreatic cancer

Research on a new way of deploying the immune system against pancreatic cancer, an exceptionally lethal cancer that has so far resisted new immunotherapies, will receive $1 million in initial funding from Stand Up to Cancer.

21 Nov 2018

Inexpensive and effective drug does not reduce major adverse cardiovascular event rates

When it comes to reducing inflammation to decrease the risk of heart disease and stroke, results from the much-anticipated Cardiovascular Inflammation Reduction Trial indicate that targeting the right inflammatory pathways in at-risk patients is crucial.

12 Nov 2018

Researchers use mRNA-loaded carriers to target genetic instructions of protein in immune cells

Delivering an effective therapeutic payload to specific target cells with few adverse effects is considered by many to be the holy grail of medical research. A new Tel Aviv University study explores a biological approach to directing nanocarriers loaded with protein "game changers" to specific cells.

30 Oct 2018

Researchers identify new potential target to inhibit progression of liver disease

Naglaa Shoukry, Ph. D., and her team have made a significant breakthrough in their research aiming to limit the progression of liver disease.

26 Oct 2018

Study shows close link between cytokine interleukin-1ß and obesity-promoted colon cancer

A new study describes the mechanistic relationship between the cytokine interleukin-1β, (IL-1β) and obesity, showing that when IL-1β levels are increased in obesity, IL-1 receptor signaling activates multiple pathways leading to colon cancer.

18 Oct 2018

Scientists work to speed regeneration and recovery of your sense of taste

When it's a significant injury, not just a hot pizza, that damages your tongue and taste buds, you appear to need a cell type best known for its inflammation-promoting skills to help restore your sense of taste.

12 Oct 2018

Study reveals new way to target HER2-negative metastatic breast cancer

A cytokine signature found in certain kinds of breast cancer cells can not only serve as a diagnostic tool for HER2-negative cancers but also offer an effective treatment target.

20 Sep 2018

Resveratrol decreases pain severity and levels of inflammatory biomarkers in osteoarthritis patients

In what researchers state is the first pilot clinical trial to assess the effects of resveratrol on pain severity and levels of inflammatory biomarkers in patients with mild to moderate knee osteoarthritis, the scientists compared treatment with a nonsteroidal anti-inflammatory drug combined with either resveratrol or placebo over 90 days.

18 Sep 2018

Case Western Reserve professor wins $2 million grant to study colorectal cancer

Lan Zhou, MD, PhD, associate professor of pathology at Case Western Reserve University School of Medicine, has received a five-year, $2 million grant from the National Cancer Institute of the National Institutes of Health to study human colorectal cancer.

14 Sep 2018

Study: Children with acute lymphoblastic leukemia are immunologically disparate at birth

Neonatal concentrations of eight detectable inflammatory markers were significantly different in children later diagnosed with B-cell precursor acute lymphoblastic leukemia (ALL) compared with controls.

14 Sep 2018

Researchers describe mechanism that sets stage for fate decision of T cells

After a pathogen infects the body, the immune system responds with a remarkable -- and remarkably complicated -- cascade of events.

14 Sep 2018

Dietary fiber may delay memory loss, brain inflammation during old age

As mammals age, immune cells in the brain known as microglia become chronically inflamed. In this state, they produce chemicals known to impair cognitive and motor function.

14 Sep 2018

New study links stress with biological disease markers in leukemia patients

Patients with chronic lymphocytic leukemia who feel more stress also have more cancer cells in their blood and elevated levels of three other markers of more advanced disease.

12 Sep 2018

Study shows B cells could play reciprocal roles in pathogenesis of systemic sclerosis

Systemic sclerosis (SSc, also known as scleroderma), a connective tissue disorder of autoimmune etiology, is characterized by excessive fibrosis in the skin and various internal organs.

30 Aug 2018

Study adds more evidence to underlying autoimmune mechanisms in type 1 diabetes

Immune reactions are usually a good thing-;the body's way of eliminating harmful bacteria and other pathogens. But people also rely on molecular "brakes," or checkpoints, to keep immune systems from attacking their own cells and organs and causing so-called autoimmune disease.

29 Aug 2018

Scientists reveal how immune system strives to protect the lungs of infants with flu

The immune system appears to put a premium on maintaining lung function in infants infected with the influenza virus by mounting a rapid response to repair damaged cells, according to research led by St. Jude Children’s Research Hospital. The findings appear today in the scientific journal Immunity.

29 Aug 2018

Delivering miRNAs to treat patients with inflammatory bowel disease

Inflammatory bowel disease, such as Crohn disease and ulcerative colitis, are chronic inflammatory diseases of unknown cause, and the number of IBD patients is on the rise.

28 Aug 2018

New findings reveal potential role of interleukin-1 alpha in risk for heart attacks, strokes

XBiotech Inc. announced today the publication of findings that point toward a white blood cell-derived interleukin-1 alpha (IL-1⍺) as a cause of blood clots that could lead to heart attacks or strokes.

28 Aug 2018

Researchers reveal an unlikely protector against growth of metastatic breast cancer

At the time of initial diagnosis, most patients with breast cancer show no signs that their cancer has spread elsewhere in the body. Yet, up to 30 percent of patients will ultimately experience metastasis, with breast cancer taking root and growing at other sites in the body, sometimes months, years or even decades later.

27 Aug 2018

Blood test could identify bladder cancer patients who may not benefit from immunotherapy

Patients who are unlikely to benefit from a commonly used immunotherapy for bladder cancer could be identified by a simple blood test, according to researchers at Brighton and Sussex Medical School.

21 Aug 2018

Interleukin 3 News and Research

Stand Up to Cancer supports potential approach to more efficiently target pancreatic cancer

Inexpensive and effective drug does not reduce major adverse cardiovascular event rates

Researchers use mRNA-loaded carriers to target genetic instructions of protein in immune cells

Researchers identify new potential target to inhibit progression of liver disease

Study shows close link between cytokine interleukin-1ß and obesity-promoted colon cancer

Scientists work to speed regeneration and recovery of your sense of taste

Study reveals new way to target HER2-negative metastatic breast cancer

Resveratrol decreases pain severity and levels of inflammatory biomarkers in osteoarthritis patients

Case Western Reserve professor wins $2 million grant to study colorectal cancer

Study: Children with acute lymphoblastic leukemia are immunologically disparate at birth

Researchers describe mechanism that sets stage for fate decision of T cells

Dietary fiber may delay memory loss, brain inflammation during old age

New study links stress with biological disease markers in leukemia patients

Study shows B cells could play reciprocal roles in pathogenesis of systemic sclerosis

Study adds more evidence to underlying autoimmune mechanisms in type 1 diabetes

Scientists reveal how immune system strives to protect the lungs of infants with flu

Delivering miRNAs to treat patients with inflammatory bowel disease

New findings reveal potential role of interleukin-1 alpha in risk for heart attacks, strokes

Researchers reveal an unlikely protector against growth of metastatic breast cancer

Blood test could identify bladder cancer patients who may not benefit from immunotherapy

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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