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Biomarkers responsible for exhaustion in cancer linked to fatigue in Parkinson's disease

Biological markers responsible for extreme exhaustion in patients with cancer have now been linked to fatigue in those with Parkinson's disease, according to new research from Rice University.

10 Aug 2018

Physical activity can help reduce risk of heart disease in older adults

Adults in their early 60s, who spend less time sitting and more time engaged in light to vigorous physical activity, benefit with healthier levels of heart and vessel disease markers, according to new research in Journal of the American Heart Association, the Open Access Journal of the American Heart Association/American Stroke Association.

9 Aug 2018

New device uses single drop of blood to diagnose mild traumatic brain injury

Every year in Europe, three million people are admitted into hospitals for suspected mild traumatic brain injury cases. Yet 90% of these patients will be able to return home safely, as no trauma has been detected.

30 Jul 2018

Newly identified target may lead to discovery of treatments for chronic inflammatory diseases

Inflammation is part of the body's natural healing process. But when it becomes chronic, inflammation can lead to cancer, Alzheimer's disease and other conditions.

26 Jul 2018

Mother's microbiome determines offspring's risk of developing autism

The risk of developing autism-spectrum disorders is determined by the mother's microbiome - the collection of microorganisms that naturally live inside us - during pregnancy, new research from the University of Virginia School of Medicine suggests.

18 Jul 2018

Viral immunotherapy shows promise to treat pediatric brain tumors

A viral immunotherapy using a herpes virus to treat brain tumors has been shown to be safe and well-tolerated in a pediatric study from the University of Alabama at Birmingham and Children's of Alabama.

4 Jul 2018

Novel, stem cell-based model mimics mechanisms of Alzheimer's disease

Scientists in Dresden, Germany, have been successful in mimicking mechanisms of Alzheimer's disease in a novel, stem cell-based model system that reproduces features of human brain tissue.

3 Jul 2018

Scientists discover protein crucial for activating inflammation

Researchers from the University of Illinois at Chicago have identified a protein that is crucial for activating inflammation -; both the good kind of inflammation that leads to healing wounds and fighting infection, as well as excessive inflammation where the immune system can damage tissues and organs.

27 Jun 2018

Novel cellular pathway may clarify how arterial inflammation develops into atherosclerosis

Investigators have identified a new cellular pathway that may help explain how arterial inflammation develops into atherosclerosis-;deposits of cholesterol, fats and other substances that create plaque, clog arteries and promote heart attacks and stroke. The findings could lead to improved therapies for atherosclerosis, a leading cause of death worldwide.

22 Jun 2018

Canakinumab reduces gout rate by more than half in atherosclerosis patients, study shows

The results of a study presented today at the Annual European Congress of Rheumatology (EULAR 2018) demonstrate that canakinumab significantly reduced the rate of gout by more than half compared to placebo, regardless of baseline serum urate level.

18 Jun 2018

Research sheds light on pathways involved in transmitting itch sensations from skin to brain

Researchers from North Carolina State University have pinpointed a particular neuropeptide associated with transmitting itch signals in mice with atopic dermatitis.

14 Jun 2018

Study: Immunization with beneficial bacteria can have long-lasting anti-inflammatory effects on the brain

Immunization with beneficial bacteria can have long-lasting anti-inflammatory effects on the brain, making it more resilient to the physical and behavioral effects of stress, according to new research by University of Colorado Boulder scientists.

7 Jun 2018

Researchers identify biomarkers that may predict risk of osteolysis

Hip replacements relieve pain and restore mobility for hundreds of thousands of patients in the United States each year, but of the more than 400,000 hip replacements performed in the U.S. annually, about 10 percent will fail within 10 to 15 years.

7 Jun 2018

Scientists identify 'hidden' driver that helps prime the anti-tumor immune response

Like exposing a crime boss whose authority has gone undetected, St. Jude Children's Research Hospital scientists have identified a hidden driver that influences production of the T cells that fight cancer and infections. The study appears today as an advance online publication in the journal Nature.

31 May 2018

Penn investigators discover source of immune molecule involved in nasal polyps, asthma

A new discovery about how the immune system responds to common sinus infections and asthma could explain why patients develop these issues in the first place and ultimately may lead to improved targeted therapies.

23 May 2018

Researchers find new method to treat severe asthma

Researchers from McMaster University and the Firestone Institute for Respiratory Health at St. Joseph's Healthcare Hamilton, together with colleagues at other partnering institutions, have developed a new method to treat severe asthma.

23 May 2018

Investigational drug offers hope of relief for celiac disease patients exposed to gluten

An investigational new drug offers hope of relief for celiac disease patients who are inadvertently exposed to gluten while on a gluten-free diet.

22 May 2018

Researchers uncover clues to early lung transplant failure

Among organ transplant patients, those receiving new lungs face a higher rate of organ failure and death compared with people undergoing heart, kidney and liver transplants. One of the culprits is inflammation that damages the newly transplanted lung.

22 May 2018

Researchers discover new disease mechanism in chronic tobacco smokers

Research published in the journal Clinical Science suggests that an immune signaling protein called interleukin-26 is increased among chronic smokers with lung disease and this involvement reveals disease mechanisms of interest for developing more effective therapy for these hard-to-treat patients.

21 May 2018

Study: Single surface protein can amplify multiple key pathways in acute myeloid leukemia

Researchers from the Albert Einstein College of Medicine in New York have discovered that a signaling protein elevated in patients with acute myeloid leukemia plays a much wider role in the disease than previously thought.

18 May 2018