Interstitial Cystitis News and Research

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Interstitial cystitis (IC) is a condition that results in recurring discomfort or pain in the bladder and the surrounding pelvic region. The symptoms vary from case to case and even in the same individual. People may experience mild discomfort, pressure, tenderness, or intense pain in the bladder and pelvic area. Symptoms may include an urgent need to urinate, a frequent need to urinate, or a combination of these symptoms. Pain may change in intensity as the bladder fills with urine or as it empties. Women’s symptoms often get worse during menstruation. They may sometimes experience pain during vaginal intercourse.

Researchers explore single-cell sequencing technologies to understand molecular mechanisms of autoimmune diseases

A new review discussed the applications of single-cell ribonucleic acid sequencing (scRNA-seq) in understanding autoimmune disorders.

17 Oct 2022

Women voice frustration over antibiotic use and limited treatment options for UTIs

Women with frequent urinary tract infections say they're unhappy with what they perceive as their doctors' overuse of antibiotics and with the limited treatment options available to them, according to a study led by researchers from UCLA and Cedars-Sinai.

4 Aug 2021

Ophthalmologists find more evidence linking common bladder drug to retinal conditions

A drug widely prescribed for a bladder condition for decades, now appears to be toxic to the retina, the light sensing tissue at the back of the eye that allows us to see.

14 Oct 2019

Alivio Therapeutics receives DoD grant to advance development of new therapy for IC/BPS

Alivio Therapeutics, an affiliate of PureTech Health plc developing therapies to treat inflammatory disorders through targeted disease immunomodulation, today announced a $3.3 million U.S. Department of Defense Technology/Therapeutic Development Award to advance Alivio's product candidate, ALV-107, for the treatment of interstitial cystitis/bladder pain syndrome with Hunner's lesions.

12 Sep 2018

Researchers use optogenetics to treat chronic pain

The finger prick from a thorn generates an immediate sensory response. In that instant, neurons at the injury site fire an electrical signal along a nerve fiber to the central nervous system. Our brain notes to avoid further encounters with thorns and the painful insult subsides.

18 Apr 2018

Newly expanded program at Rush offers relief from pelvic floor problems

Trouble with urine or bowel control, bladder pain, recurring urinary tract infections, constipation and other sexual function issues frequently can be traced to a dysfunctional pelvic floor -- the layer of muscles that support the bladder and bowel in men, and bladder, bowel and vagina in women.

6 Apr 2018

Antibiotics could benefit women suffering from chronic bladder pain

Antibiotics can successfully help rid a patient of chronic urinary tract infection symptoms. This is the finding of a new clinical study led by Sheela Swamy of University College London in the UK.

20 Mar 2018

Researchers develop simple urine-based test for rapid and accurate detection of Zika virus

There is no vaccine. No medication. And, no quick, reliable test for Zika virus … until now. Babies born with the virus often have lifelong, devastating birth defects.

15 May 2017

SLU scientist examines potential biomarkers for pain linked to debilitating health conditions

With new funding from The Mayday Fund, a Saint Louis University researcher will leverage her discovery of a pain pathway to determine if either of two key molecules can be used as biomarkers for pain associated with four debilitating health conditions: chemotherapy-induced peripheral neuropathy, endometriosis, interstitial cystitis and vulvodynia.

16 Feb 2017

New ICN Food List app can help people struggling with urinary tract food sensitivity

If you're scared to drink a cup of coffee out of fear that you'll spend the day in the restroom, you're not alone. Mild urinary frequency and urgency are common but for patients with urinary disorders, these same foods can provoke days of pain and discomfort. A new android application, the ICN Food List, seeks to change that by giving patients a reference guide that they can easily use while shopping and eating out at restaurants.

15 Dec 2015

Imprimis, Advanced Dosage sign license agreement for proprietary compounded ophthalmic formulations

Imprimis Pharmaceuticals, Inc., a pharmaceutical company focused on the development and commercialization of proprietary compounded drug formulations, today announced that it has entered into a license agreement with Advanced Dosage Forms, Inc. to expand Imprimis' proprietary ophthalmic injectable and combination topical compounded formulations into Canada. Under the agreement, the licensee has the rights to formulate, market and sell these formulations across Canada.

12 Aug 2015

Botulinum toxin A effective for treating bladder disorders

While Botulinum toxin A (BTX-A), known to the public as Botox, is commonly associated with smoothing wrinkles for a more youthful appearance, three studies presented at the 110th Annual Scientific Meeting of the American Urological Association are proving BTX-A to be more than just a cosmetic solution.

17 May 2015

Imprimis has exclusive US commercial rights for patented Hep-Lido-A formulation

Imprimis Pharmaceuticals, Inc., a pharmaceutical company focused on the development and commercialization of proprietary compounded drug formulations, today announced it now has the exclusive US commercial rights to the patented compounded alkalinized lidocaine and heparin formulation ("Hep-Lido-A" or "HLA") for the treatment of interstitial cystitis ("IC"), commonly referred to as painful bladder syndrome ("PBS").

28 Apr 2015

News study finds association between chronic fatigue syndrome and early menopause

A newfound link between chronic fatigue syndrome (CFS) and early menopause was reported online today in Menopause, the journal of The North American Menopause Society.

4 Feb 2015

Urinary nerve growth factor shows diagnostic value

Urinary nerve growth factor could be a useful biomarker for the diagnosis of overactive bladder and a predictive biomarker to help guide treatment, Chinese researchers believe.

17 Sep 2014

Loyola announces opening of new acupuncture clinic for patients with pelvic health disorders

Loyola University Health System will open an acupuncture clinic for men and women with pelvic health disorders this fall. The clinic will use acupuncture to treat patients with common conditions such as pelvic pain, nausea from pelvic surgery, interstitial cystitis, painful bladder syndrome, postoperative pain, prostatitis and overactive bladder.

11 Sep 2014

Scientists aim to understand and treat painful bladder condition

Taking advantage of technology that can analyze tissue samples and measure the activity of thousands of genes at once, scientists at Wake Forest Baptist Medical Center are on a mission to better understand and treat interstitial cystitis (IC), a painful and difficult-to-diagnose bladder condition.

12 Aug 2014

OAB and interstitial cystitis/bladder pain syndrome show considerable overlap

There is considerable overlap between symptoms in patients with interstitial cystitis/bladder pain syndrome and those with overactive bladder, US researchers have shown.

23 Jun 2014

Squatty Potty toilet stool improves severity of constipation symptoms

When used as a treatment, the original Squatty Potty (www.squattypotty.com) toilet stool significantly improves the severity of constipation symptoms within one month of use among 84 percent of the participants of a recently released scientific study.

4 Jun 2014

NAFC honors Dr. Alan J. Wein with Rodney Appell Continence Care Champion award

The National Association For Continence presented Alan J. Wein, MD, FACS, PhD(hon) with its Rodney Appell Continence Care Champion award at the Society of Urodynamics, Female Pelvic Medicine, & Urogenital Reconstruction's 2014 Annual Meeting in Orlando, FL on February 28, 2014.

4 Mar 2014