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Chronic pain may occur when receptors migrate from nerve cell's surface to inner chambers

A study led by Columbia University Medical Center has shown that chronic pain may occur when pain receptors migrate from the nerve cell's surface to the cell's inner chambers, out of the reach of current pain medications.

1 Jun 2017

TUM scientists develop new pH sensor that provides insights into tumor metabolism

Tumors, inflammation and circulatory disorders locally disturb the body's acid-base balance. These changes in pH value could be used for example to verify the success of cancer treatments.

12 May 2017

Study uncovers potential new therapeutic targets for HCV infections

An international study led by researchers at Monash University' Biomedicine Discovery Institute (BDI) has shone light on the way the Hepatitis C Virus (HCV) hijacks the communication systems in the host cells it infects, uncovering potential new therapeutic targets for the disease.

8 May 2017

IDIBELL researchers reveal role of endoplasmic reticulum in cell death process due to starvation

Researchers from the Cell death group of the Bellvitge Biomedical Research Institute, led by Dr. Cristina Muñoz-Pinedo, have characterized the cell death process due to starvation, in which the endoplasmic reticulum plays a leading role.

3 May 2017

Light can be used to control cellular functions, optogenetics study shows

Light can be used as an accurate method to control gene expression, shows groundbreaking optogenetics study by University of Colorado, Duke University and University of Helsinki researchers.

21 Apr 2017

Atomic resolution structure of key molecule may contribute to drug discovery for devastating conditions

Culminating a nearly 10 year effort, researchers have determined the atomic resolution structure of a key molecule that translates signals from a cell's local environment into a language that the cell can understand and use.

18 Apr 2017

New nanowire technology may serve as platform to screen drugs for neurological diseases

A team led by engineers at the University of California San Diego has developed nanowires that can record the electrical activity of neurons in fine detail.

11 Apr 2017

New finding on key protein opens door to potential therapies for chronic illnesses

Scientists have determined unexpected characteristics of a key protein linked to blood pressure control and to nerve growth, pain control and heart tissue regeneration. The findings, published April 5 online in the journal Nature, opens doors to potential new therapies to control cardiovascular disease and pain.

6 Apr 2017

MSU and Venn Therapeutics develop promising therapy to delay B16 melanoma tumor growth

Michigan State University researchers presented promising cancer therapy results at the American Association for Cancer Research International Meeting in Washington, DC.

5 Apr 2017

Researchers identify mechanism to recover aging of Progeria patients

DGIST's research team has identified a mechanism that can recover the aging of patients with Hutchinson-Gilford Progeria Syndrome. DGIST announced that the Chair Professor Park SangChul of New Biology and the research team led by Professor Lee YoungSam has discovered a drug that can improve the aging of HGPS patients and identified the mechanism of aging recovery by using the drug.

4 Apr 2017

Researchers show how cellular stress regulates production of hemoglobin

Our ability to breathe oxygen is critical to our survival. This process is mediated by the hemoglobin in our blood, which carries oxygen. Since air contains less oxygen on high mountains, the body is under pressure to make hemoglobin rapidly -- a stressful time.

4 Apr 2017

Researchers discover key to reveal secret of reversible aging recovery

DGIST's research team discovered substances that can induce reversible aging* recovery and identified an aging recovery mechanism using these substances.

3 Apr 2017

Research unravels how cytokines prevent multi-organ damage during parasitic infection

Cytokines are proteins secreted by several types of immune cells in response to infection, inflammation, or injury. Interleukin-17 (IL-17) is one such cytokine that causes inflammation, by controlling the production of other cytokines and mobilizing a type of white blood cell (neutrophil) that fights infections.

3 Apr 2017

Pyrethroid pesticide exposure may cause earlier sexual maturity in boys

Environmental exposure to common pesticides may cause boys to reach sexual maturity earlier, researchers have found. They will present their study results Saturday at the Endocrine Society's 99th annual meeting in Orlando, Fla.

2 Apr 2017

German scientists design molecular paintbrush technique to control and monitor key intracellular processes

The plasma membrane serves as a major hub for signal cascades to control crucial cellular processes. But it is a fluid medium, which makes the signaling processes difficult to monitor.

31 Mar 2017

Fluctuation in intracellular calcium ion concentration impacts brain shape

The first step in shaping the brain is that the neural plate, a sheet-like cell layer, curves to form the neural tube. Assistant Professor Makoto Suzuki of the National Institute for Basic Biology, Professor Naoto Ueno, and their colleagues have shown that during the process of neural tube formation a transient increase in the concentration of calcium ions in cells causes these morphological changes and is essential for neural tube formation.

30 Mar 2017

LSTM scientists describe new approach to screening potential TB treatments

Scientists from LSTM's Research Centre for Drugs and Diagnostics (RCDD) have described in a paper published today in Scientific Reports, a new way of screening potential treatments for Tuberculosis (TB) which may assist in the identification and prioritisation of new therapies which could potentially reduce the duration of current TB treatment.

29 Mar 2017