Ion Channel News and Research

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More sensitive electrophysiology tools needed to study cancer cell populations

Bioelectricity of Cancer, a special issue of the peer-reviewed journal Bioelectricity, has just been published. Two promising discoveries are well delineated: an ultra-sensitive tool to detect cancer and a new therapeutic target for cancer immunotherapy.

9 Oct 2019

KIT researchers develop close-to-reality computer models of the heart

Digital simulations of human organs can be used to study the development of diseases and to customize therapies for patients.

4 Oct 2019

Researchers observe the working of protein associated with numerous health problems

For the first time, researchers have observed at the molecular level how a protein associated with numerous health problems works.

3 Oct 2019

UC Davis research team receives NIH grant to develop novel drugs for treating pain

A UC Davis research team, led by Vladimir Yarov-Yarovoy and Heike Wulff, will receive a $1.5 million grant from the National Institutes of Health to develop a novel class of peptides that are better at treating pain and don't have the side effects of opioids.

1 Oct 2019

Physiologists, researchers to discuss factors underlying cardiovascular disease at APS conference

International physiologists and researchers studying the kidney, high blood pressure and related medical conditions will convene next week at the American Physiological Society (APS) Aldosterone and ENaC in Health and Disease: The Kidney and Beyond Conference in Estes Park, Colo.

25 Sep 2019

$1.5 million grant from BRAIN Initiative will help develop new tools to study astrocytes

In the brain, cells called astrocytes are at least as abundant as neurons, but are much less understood.

27 Aug 2019

Scientists take first step towards digital map of the ion channels in the brain

Researchers have mapped the molecular workings of voltage-gated potassium ion channels within the brain.

16 Aug 2019

Researchers identify new transmembrane protein as chloride ion channel

In the human body the salt content of cells and their surrounding is regulated by sophisticated transport systems.

14 Aug 2019

Neuronal gene mutations may be linked to seizures associated with Long QT Syndrome

Researchers identified a gene in fruit flies that helps prevent the hyperexcitability of specific neurons that trigger seizures. In humans, mutations in the gene may be linked to seizures associated with Long QT Syndrome.

From PLOS ONE 13 Aug 2019

Neuronal gene malfunction is behind seizures associated with long QT syndrome, study suggests

Most people with a medical condition called long QT syndrome have a mutation in a gene that causes bouts of fast, chaotic heartbeats.

9 Aug 2019

Hinge-like protein may unlock new pathways for cystic fibrosis treatment

In recent decades, treatment options for people with cystic fibrosis have improved dramatically. The newest drugs, known as potentiators, target a protein called cystic fibrosis transmembrane conductance regulator, which is mutated in people with the disease.

10 Jul 2019

Nanion launches HTS automated patch clamp platform

The SyncroPatch 384i is a giga-ohm seal HTS automated patch clamp platform designed for flexibility, ease-of-use and reliability.

From Nanion Technologies 25 Jun 2019

E-cigarette vaping with nicotine appears to impair mucus clearance

E-cigarette vaping with nicotine appears to hamper mucus clearance from the airways, according to new research published online in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine.

7 Jun 2019

Neurons rely on their own electrical signals to keep track of normal functions

Nerve cells, or neurons -- specifically the "workhorse cells" involved in walking, breathing and chewing -- can adjust to changes in the body, but they never stop working unless there is an fatal injury.

10 May 2019

Discovery about cold sensing could pave way for new pain relief drugs

Researchers at UCL have shown for the first time that mammals detect different intensities of cold using distinct sensory neuron systems, a finding which could lead to the development of new drugs to treat cold pain.

24 Apr 2019

Researchers annotate key neuronal proteins in lamprey genome

The lamprey, an eel-like primitive vertebrate, is a popular organism for neurobiology studies because it has a relatively simple nervous system.

16 Apr 2019

Metrion Biosciences announces closure of funding round

Metrion Biosciences Ltd, the specialist ion channel contract research and drug discovery company, announced today that it has completed a fully subscribed funding round on 14 March.

From Metrion Biosciences Limited 2 Apr 2019

Promising gene therapy could restore vision in humans

It was surprisingly simple. University of California, Berkeley, scientists inserted a gene for a green-light receptor into the eyes of blind mice and, a month later, they were navigating around obstacles as easily as mice with no vision problems.

15 Mar 2019

New simulations offer insights on vital atomic-scale drug-cardiac cells interactions

To unravel the mysterious mechanisms of drug potency for the treatment of cardiac arrhythmias, a group of researchers at UC Davis have developed novel simulations that provide insights on vital atomic-scale drug-cardiac cells interactions.

8 Feb 2019

Metrion collaborates with LifeArc on neuroscience-focused ion channel drug discovery project

Metrion Biosciences and LifeArc have entered into a collaboration agreement for an ion channel drug discovery project in the field of neuroscience.

From Metrion Biosciences Limited 30 Jan 2019