Jaundice News and Research

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Jaundice, also known as icterus (attributive adjective: icteric), is a yellowish discoloration of the skin, the conjunctival membranes over the sclerae (whites of the eyes), and other mucous membranes caused by hyperbilirubinemia (increased levels of bilirubin in the blood).

Enzyme discovery could reduce Kaposi sarcoma tumour growth and lead to drugs suitable for treating other viral cancers

A report in the Journal of Biological Chemistry shows that inhibition of heme oxygenase-1, an enzyme involved in iron metabolism, reduces Kaposi sarcoma tumor growth. This discovery could result in the production of new drugs to treat this and other viral cancers.

28 Apr 2006

Average pregnancy in the U.S. is now 39 weeks

The most common length of pregnancy in the United States is now 39 weeks, a week shorter than the traditional definition of a full-term pregnancy. This shift occurred between 1992 and 2002, according to a new analysis by the March of Dimes published this month in a special supplement of the journal "Seminars in Perinatology."

23 Mar 2006

Gut protein protects against infection and intestinal breakdown

A protein that binds to bile in the small intestine may hold the key to preventing infection and intestinal breakdown in people with conditions such as obstructive jaundice or irritable bowel syndrome, researchers at UT Southwestern Medical Center have discovered.

12 Feb 2006

Drug company warns of risk of liver problems with antidepressant

The warning about possible liver-related problems with the depression drug, Cymbalta, has been expanded and doctors are being cautioned against its use in chronic liver disease patients.

18 Oct 2005

Significant step forward in the genome era

In what promises to be a significant step forward in the genome era, the National Human Genome Research Institute (NHGRI) today announced plans to devote a portion of its large-scale sequencing capacity to efforts aimed at identifying the genetic roots of specific diseases that have long eluded gene hunters.

17 Oct 2005

3D gradient-echo MRI examinations useful in detecting most lethal of all major cancers

The study included 57 patients who had clinical symptoms of pancreatic cancer. All had contrast enhanced 3D gradient-echo MRI examinations.

6 Sep 2005

Top doctors in UK fear for teens with change in alcohol laws

Doctors in the UK are concerned that any relaxation in the alcohol laws will only serve to cause a rise in cirrhosis among young people.

30 Aug 2005

A study analyzes the most important factors leading to death or liver transplant in drug-induced liver disease

Drug-induced liver disease (DILD), a potential complication seen with some medications, is usually not life-threatening, but may occasionally be more severe with a high mortality, requiring a liver transplant in selected cases.

18 Jul 2005

Targeted program drastically reduced hepatitis A in U.S.

According to a newly released study, the number of cases of hepatitis A have fallen by 76 percent in the United States since a vaccination campaign targeted children in communities with the highest rates of the disease.

13 Jul 2005

Findings may help scientists improve the existing vaccine for yellow fever

In one of the first molecular studies of the human antibody response to yellow fever, Howard Hughes Medical Institute (HHMI) researchers and their colleagues have found the crucial bit of virus that people's immune systems need to spot and quash this often-fatal re-emerging disease.

16 Jun 2005

Self-expanding metal tubes or stents are a safe and effective treatment for obstructive jaundice

One key goal of treating pancreatic cancer, which is often fatal within a year, is making sure patients have a good quality of life with as few complications as possible. This is especially important if they are candidates for surgical removal of the cancer.

2 May 2005

Marburg virus - 275 confirmed cases

The World Health Organization (WHO) and health authorities in Angola have confirmed 275 cases including 255 deaths, in an outbreak of Marburg virus in north-western Angola since April 27 this year.

2 May 2005

Findings from perinatal HIV prevention study in Uganda are valid

A Ugandan drug trial's findings that the AIDS medication nevirapine is effective and safe in preventing HIV transmission from mother to unborn child during birth were well-supported, according to a new, independent analysis by the Institute of Medicine of the National Academies.

12 Apr 2005

Data which showed that nevirapine effectively prevents many infants from contracting HIV from their infected mothers, are sound and reliable

10 Apr 2005

CDC experts sent to Angola to help with Marburg epidemic

In an effort to control the Marburg virus outbreak in Angola, Health officials from the Centers for Disease Control and Prevention in Atlanta will assist the World Health Organization by going to Angola to help with outbreak investigation, infection control and laboratory diagnosis of the disease.

30 Mar 2005

Branding treatment in India should be banned

A letter in this weeks BMJ reports on how researchers are urging rural clinics in India to stop the superstitious practice known as 'branding treatment'.

27 Feb 2005

Health risks increase in Guyana with leptospirosis

Leptospirosis has become a health concern in Guyana, as the number of cases continues to rise and 43 people were being treated for suspected cases of the bacterial disease, which is usually caused by exposure to water contaminated with the urine of infected animals.

8 Feb 2005