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Researchers identify stem cells in urine can be directed to become multiple cell types

Could harvesting stem cells for therapy one day be as simple as asking patients for a urine sample? Researchers at Wake Forest Baptist Medical Center's Institute for Regenerative Medicine and colleagues have identified stem cells in urine that can be directed to become multiple cell types.

31 Jul 2013

AstraZeneca, FibroGen partner to develop, commercialize anemia drug candidate FG-4592

AstraZeneca and FibroGen today announced that they have entered into a strategic collaboration to develop and commercialize FG-4592, a first-in-class oral compound in late stage development for the treatment of anemia associated with chronic kidney disease and end-stage renal disease.

31 Jul 2013

Male and female rats show different patterns of kidney gene expression throughout their lives

Male and female rats show different patterns of kidney gene expression throughout their lives, a study in the open access journal Biology of Sex Differences reveals. The finding could help explain some of the gender differences observed in human renal disease, and lead to improved biomarkers of kidney function.

31 Jul 2013

FibroGen, Astellas initiate Phase 2 study of ASP1517/FG-4592 for treatment of anemia linked with CKD

Astellas Pharma Inc. (Tokyo:4503) (Astellas) and FibroGen, Inc. (FibroGen) announced today the initiation of a Phase 2 clinical study in Japan of ASP1517/FG-4592 for treatment of anemia associated with chronic kidney disease (CKD) in patients on dialysis.

31 Jul 2013

NPS MedicineWise finds little or no clinical benefit in switching to rivaroxaban for stroke prevention

With oral anticoagulant rivaroxaban set to be subsidised under the Pharmaceutical Benefits Scheme (PBS) for preventing stroke, NPS MedicineWise is urging people to talk to their doctor before stopping or making any changes to their anticoagulant medicines.

30 Jul 2013

Adolescent patients who received kidney transplant appear to be at increased risk for transplant failure

Patients who received their first kidney transplant at ages 14 to 16 years appear to be at increased risk for transplant failure, with black adolescents having a disproportionately higher risk of graft failure, according to a report published by JAMA Internal Medicine, a JAMA Network publication.

30 Jul 2013

NIH expands CRIC study to identify risk factors for progression of early stage CKD

Researchers from the Chronic Renal Insufficiency Cohort study are embarking on another five years of work to identify risk factors for progression of early stage chronic kidney disease, better understand the importance of reduced kidney function in older persons, and learn what role CKD may play in other illnesses that require hospitalization. CRIC is supported by the National Institutes of Health.

30 Jul 2013

Gout, uric acid levels and risk of death: an interview with Professor Austin Stack, Graduate Entry Medical School, University of Limerick

Gout is a relatively common arthritic disease that affects about 4% (I in 25) of the population. It results from the deposition of uric acid in joints due to elevated blood levels and a resulting inflammation ensues which is very painful.

26 Jul 2013

Frequency, duration of patient-doctor contact important for improving health of dialysis patients

Both the frequency and duration of patient-doctor contact during dialysis care vary appreciably across countries, and facilities with more frequent and longer contact had fewer patient deaths and hospitalizations, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology.

26 Jul 2013

NxStage Medical revenue increases 11% to $65.5 million in Q2 2013

NxStage Medical, Inc., a leading manufacturer of innovative dialysis products, today reported second quarter financial results with total revenue at the top end of its guidance range.

25 Jul 2013

EKF Diagnostics introduces STAT-Site M ß-HB strip test for DKA assessment

EKF Diagnostics, the global in vitro diagnostics business, announces the worldwide launch of the new STAT-Site M ß-HB, following successful CE marking.

From EKF Diagnostics 25 Jul 2013

Study provides more reliable estimate of the likely risk of disability associated with diabetes

Older adults with diabetes are at least 50% more likely to have a physical disability than those without diabetes, according to the results of a new systematic review and meta-analysis published in The Lancet Diabetes & Endocrinology.

25 Jul 2013

NOXXON completes patient recruitment of NOX-E36 Phase IIa trial for treatment of diabetic nephropathy

NOXXON Pharma today announced the successful completion of patient recruitment of its NOX-E36 Phase IIa clinical trial for the treatment of diabetic nephropathy. NOX-E36 is a Spiegelmer® that binds and neutralizes CCL2/MCP-1 (C-C Chemokine Ligand / Monocyte Chemoattractant Protein-1), a pro-inflammatory chemokine that plays an important role in the progression of diabetic nephropathy, the most common single cause of chronic kidney failure and end-stage renal disease.

25 Jul 2013

Study may lead to personalized treatments for mitochondrial energy disorders

Researchers have identified a master network of signaling molecules that acts like a "fuse box" to regulate the cellular effects of defective energy flow in mitochondrial respiratory chain diseases—a diverse set of difficult-to-treat genetic-based energy disorders.

25 Jul 2013

New data questions surgical options for treating kidney cancer

Surgery is often the first step in treating kidney cancer, and new data from the University of Rochester Medical Center, which contradicts earlier research, questions whether removal of only the tumor (partial nephrectomy) is better than removing the entire kidney (radical nephrectomy).

25 Jul 2013

Study shows obese kidney failure patients derive survival advantage from transplantation

Most obese individuals with kidney failure can prolong their lives by receiving a kidney transplant, although this survival benefit is lower in severely obese individuals. That's the conclusion of a new study published in the American Journal of Transplantation.

25 Jul 2013

Study reveals African bats may play a role in evolution of MERS-CoV predecessor viruses

The MERS-coronavirus is regarded as a dangerous novel pathogen: Almost 50 people have died from infection with the virus since it was first discovered in 2012. To date all cases are connected with the Arabian peninsula. Scientists from the University Bonn (Germany) and South Africa have now detected a virus in the faeces of a South African bat that is genetically more closely related to MERS-CoV than any other known virus.

25 Jul 2013

Mortality rates declining among dialysis patients despite rise in coronary artery disease, study finds

A new study led by researchers at the University of Limerick’s Graduate Entry Medical School has found that deaths among dialysis patients are falling despite a rise in coronary artery disease.

24 Jul 2013

Child cancer survival: an interview with Prof Kathy Pritchard-Jones, University College London

Back in the early 1960s, just before chemotherapy really started to be used, only about 30% of children survived cancer. That was mainly because they had cancers that were amenable to surgery.

24 Jul 2013

Report shows that fatal rabies virus is transmitted through transplanted kidney

An investigation into the source of a fatal case of raccoon rabies virus exposure indicates the individual received the virus via a kidney transplant 18 months earlier, findings suggesting that rabies transmitted by this route may have a long incubation period, and that although solid organ transplant transmission of infectious encephalitis is rare, further education to increase awareness is needed, according to a study in the July 24/31 issue of JAMA.

24 Jul 2013

Kidney News and Research

Researchers identify stem cells in urine can be directed to become multiple cell types

AstraZeneca, FibroGen partner to develop, commercialize anemia drug candidate FG-4592

Male and female rats show different patterns of kidney gene expression throughout their lives

FibroGen, Astellas initiate Phase 2 study of ASP1517/FG-4592 for treatment of anemia linked with CKD

NPS MedicineWise finds little or no clinical benefit in switching to rivaroxaban for stroke prevention

Adolescent patients who received kidney transplant appear to be at increased risk for transplant failure

NIH expands CRIC study to identify risk factors for progression of early stage CKD

Gout, uric acid levels and risk of death: an interview with Professor Austin Stack, Graduate Entry Medical School, University of Limerick

Frequency, duration of patient-doctor contact important for improving health of dialysis patients

NxStage Medical revenue increases 11% to $65.5 million in Q2 2013

EKF Diagnostics introduces STAT-Site M ß-HB strip test for DKA assessment

Study provides more reliable estimate of the likely risk of disability associated with diabetes

NOXXON completes patient recruitment of NOX-E36 Phase IIa trial for treatment of diabetic nephropathy

Study may lead to personalized treatments for mitochondrial energy disorders

New data questions surgical options for treating kidney cancer

Study shows obese kidney failure patients derive survival advantage from transplantation

Study reveals African bats may play a role in evolution of MERS-CoV predecessor viruses

Mortality rates declining among dialysis patients despite rise in coronary artery disease, study finds

Child cancer survival: an interview with Prof Kathy Pritchard-Jones, University College London

Report shows that fatal rabies virus is transmitted through transplanted kidney

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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