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Clinical trial to study immunosuppressant tacrolimus against generics

A new study at the University of Cincinnati seeks to end the questions over generic-vs.-brand for a common immunosuppressive drug for transplant patients, tacrolimus.

20 Oct 2012

Kaiser Permanente Research Affiliates receives prestigious designation from AHRQ

A new research collaboration led by Kaiser Permanente has received a prestigious designation from the federal Agency for Healthcare Research and Quality to serve of as one of the nation's 11 Evidence-based Practice Centers.

20 Oct 2012

NIH-funded study of weight loss in adults with type 2 diabetes finds no cardiovascular benefits

An intensive diet and exercise program resulting in weight loss does not reduce cardiovascular events such as heart attack and stroke in people with longstanding type 2 diabetes, according to a study supported by the National Institutes of Health.

20 Oct 2012

Damage of endothelial glycocalyx may lead to heart troubles in kidney failure patients

Individuals with kidney failure often develop heart problems, but it's not clear why. A study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN) provides evidence that their kidneys' inability to excrete waste products in the urine, which leads to build-up of these products in the blood, may damage the sugary lining of blood vessels and lead to heart troubles.

20 Oct 2012

Daily whole body vibration may combat prediabetes in adolescents

Daily sessions of whole-body vibration may combat prediabetes in adolescents, dramatically reducing inflammation, average blood glucose levels and symptoms such as frequent urination, researchers report.

20 Oct 2012

Liver x receptor plays an important role in diabetic nephropathy

Researchers have discovered a new therapeutic target for diabetic nephropathy, the leading cause of kidney failure.

19 Oct 2012

Study hopes to improve the outlook for native Americans with kidney disease

Americans have a 1 in 10 chance of suffering from kidney disease, according to statistics from the Centers for Disease Control and Prevention. For Native Americans, the risk doubles.

19 Oct 2012

Longer looks: A Nobel for the economist behind the National Resident Matching Program; Helping Charlie end his life

A noted economist at Harvard, (Al) Roth was responsible for algorithms that matched medical students with their residency programs, children with their schools in Boston, and more recently, compatible kidney donors and transplant patients in paired donations.

19 Oct 2012

Active surveillance of small kidney masses offers similar cancer outcomes to radical or partial surgery

Active surveillance of small kidney masses is a safe and effective alternative to immediate surgery, with similar overall and cancer specific survival rates, according to a study published in the November issue of the urology journal BJUI.

19 Oct 2012

Phase 3 study of INLYTA fails to meet primary endpoint in treatment-naïve patients with RCC

Pfizer Inc. announced today that a Phase 3 study of INLYTA (axitinib) did not meet its primary endpoint of demonstrating statistically significantly longer progression-free survival, versus sorafenib, in treatment-naïve patients with advanced renal cell carcinoma.

18 Oct 2012

Chloride-restrictive intravenous fluids reduce risk for kidney injury

The restrictive use of chloride in intravenous fluids reduces the risk for acute kidney injury and renal replacement therapy, research shows.

18 Oct 2012

Study: 3 in 10 kidney transplant patients require readmission to hospital within 30 days of discharge

Three in 10 patients receiving a kidney transplant require readmission to the hospital within 30 days of discharge following surgery, according to a Johns Hopkins analysis of six years of national data.

17 Oct 2012

Chloride-restrictive intravenous strategy may decrease incidence of AKI among critically ill patients

In a pilot study assessing the effect of different levels of chloride in intravenous fluids administered to critically ill patients in an intensive care unit, restricting the amount of chloride administration was associated with a significant decrease in the incidence of acute kidney injury and the use of renal replacement therapy, according to a study in the October 17 issue of JAMA.

17 Oct 2012

UMass professor receives $1 million LRI grant for lupus research

The Lupus Research Institute (LRI) has named University of Massachusetts Medical School Professor of Medicine Ann Marshak-Rothstein, MD, one of two recipients of the first LRI Distinguished Innovator Awards.

17 Oct 2012

Resverlogix commences RVX-208 Phase 2 trial in pre-diabetes mellitus

Resverlogix Corp. today announced that it has initiated an exploratory Phase 2 clinical trial in patients with pre-diabetes mellitus to examine the effects of RVX-208 and ApoA-I production on glucose metabolism.

17 Oct 2012

Nine Sydney researchers to receive funding for biomedical research projects

The Ramaciotti Foundations will award nearly $645,000 in grants to nine Sydney researchers at a gala dinner tonight, to support continued outstanding biomedical research. The Ramaciotti Foundations will award over $1.6 million to 23 recipients at the annual awards evening in Brisbane.

16 Oct 2012

CKD may thicken carotid arteries, raise CVD risk in children

Findings from a US study show that carotid intima-media thickness is significantly higher among children with mild-to-moderate chronic kidney disease than in children without the kidney condition.

16 Oct 2012

Exercise and healthy eating reduce body fat and preserve muscle in adults

Exercise and healthy eating reduce body fat and preserve muscle in adults better than diet alone, according to a study funded and conducted by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), part of the National Institutes of Health.

16 Oct 2012

Data from Genkyotex’s GKT137831 Phase I studies to be presented at Kidney Week 2012

Genkyotex, the leading developer of NOX inhibitors to treat oxygen-radical mediated diseases, announced today that data from single and multiple dose Phase I studies with the NOX 1 and 4 inhibitor, GKT137831, will be presented at Kidney Week 2012.

15 Oct 2012

Few physicians recommend active surveillance for low-risk prostate cancer

Few physicians recommend active surveillance for low-risk prostate cancer rather than pursuing surgery or radiation, according to a Mayo Clinic study being presented at the North Central Section of the American Urological Association's annual meeting Oct. 10-13 in Chicago.

15 Oct 2012

Kidney News and Research

Clinical trial to study immunosuppressant tacrolimus against generics

Kaiser Permanente Research Affiliates receives prestigious designation from AHRQ

NIH-funded study of weight loss in adults with type 2 diabetes finds no cardiovascular benefits

Damage of endothelial glycocalyx may lead to heart troubles in kidney failure patients

Daily whole body vibration may combat prediabetes in adolescents

Liver x receptor plays an important role in diabetic nephropathy

Study hopes to improve the outlook for native Americans with kidney disease

Longer looks: A Nobel for the economist behind the National Resident Matching Program; Helping Charlie end his life

Active surveillance of small kidney masses offers similar cancer outcomes to radical or partial surgery

Phase 3 study of INLYTA fails to meet primary endpoint in treatment-naïve patients with RCC

Chloride-restrictive intravenous fluids reduce risk for kidney injury

Study: 3 in 10 kidney transplant patients require readmission to hospital within 30 days of discharge

Chloride-restrictive intravenous strategy may decrease incidence of AKI among critically ill patients

UMass professor receives $1 million LRI grant for lupus research

Resverlogix commences RVX-208 Phase 2 trial in pre-diabetes mellitus

Nine Sydney researchers to receive funding for biomedical research projects

CKD may thicken carotid arteries, raise CVD risk in children

Exercise and healthy eating reduce body fat and preserve muscle in adults

Data from Genkyotex’s GKT137831 Phase I studies to be presented at Kidney Week 2012

Few physicians recommend active surveillance for low-risk prostate cancer

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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