Kidney News and Research

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TXNIP protein provides best available target for therapies against diabetes, Wolfram syndrome

Inflammation and cell stress play important roles in the death of insulin-secreting cells and are major factors in diabetes. Cell stress also plays a role in Wolfram syndrome, a rare, genetic disorder that afflicts children with many symptoms, including juvenile-onset diabetes.

8 Aug 2012

Frailty may explain early dialysis initiation and mortality link

A high prevalence of frailty among patients starting dialysis may help to explain why early dialysis initiation in chronic kidney disease is associated with a reported increase in mortality, say US researchers.

7 Aug 2012

Less is definitely more for men who undergo nephrectomy

Researchers have identified a link between complete kidney removal and erectile dysfunction, a manifestation of endothelial dysfunction that often precedes cardiovascular disease.

6 Aug 2012

Potential new drug to treat common inherited kidney disease

Scientists at UC Santa Barbara have demonstrated in the laboratory that a new drug is effective in treating a very common kidney disease -- although it will be a few years before it becomes available for clinical testing. The findings resulted from a collaboration between UCSB and a biotech firm based in Indiana. The study is published in this week's Journal of the American Society of Nephrology.

3 Aug 2012

Research roundup: Massachusetts health reform; Role of race and insurance in kidney transplantation

Access to Care After Massachusetts' Health Care Reform: A Safety Net Hospital Patient Survey -- Policy analysts have long said that Massachusetts and its 2006 health reform law provide great insight into the federal health law and how its expansion of insurance coverage will play out.

3 Aug 2012

Depression in kidney cancer patients associated with survival and inflammatory gene regulation

Research from The University of Texas MD Anderson Cancer Center has found that symptoms of depression in patients with newly diagnosed metastatic kidney cancer are associated with survival and inflammatory gene regulation may explain this link.

3 Aug 2012

Researchers discover surprising and unexpected plasticity in the embryonic endothelium

UCLA stem cell researchers have found for the first time a surprising and unexpected plasticity in the embryonic endothelium, the place where blood stem cells are made in early development.

3 Aug 2012

Iced tea can lead to formation of kidney stones

This is the peak season for drinking iced tea, but a Loyola University Medical Center urologist is warning the popular drink can contribute to painful kidney stones.

3 Aug 2012

Weill Cornell Medical College receives NCATS grant to fund Clinical and Translational Science Center

Weill Cornell Medical College has received $49.6 million from the National Center for Advancing Translational Sciences (NCATS), of the National Institutes of Health (NIH), to fund its Clinical and Translational Science Center (CTSC).

3 Aug 2012

Link between skeletal development and Fraser syndrome deafness in mammals

Using mutant zebra fish, researchers studying the earliest formation of cartilage of the mouth believe they may have gotten a look at a mechanism involved in a genetic defect linked to Fraser syndrome deafness in humans.

1 Aug 2012

People with diabetes, hypertension and hyperlipidemia have difficultly managing all 3 conditions

Most people who have diabetes, high blood pressure, and high cholesterol have difficultly managing all three conditions; indeed, success is fleeting for those who do manage all three, according to a Kaiser Permanente Institute for Health Research study that appears online in the American Heart Association journal Circulation: Cardiovascular Quality and Outcomes.

1 Aug 2012

Researchers discover new approach to treat two lethal metastatic cancers

A potentially powerful new approach to treating two lethal metastatic cancers - triple negative breast cancer and clear cell renal cell carcinoma, the most common form of kidney cancer - has been discovered by researchers at Mayo Clinic in Florida.

1 Aug 2012

Biomimetic bioartificial livers and cell toxicity assays: an interview with Dr. Joris Braspenning, CEO Medicyte

Biomimetic bioartificial livers are liver organoids based on synthetic equivalents of the human extracellular matrix (ECM) which will be seeded with human cells.

1 Aug 2012

Obesity and heart disease risk in children: an interview with Joana Kist-van Holthe

'What defines obesity in children' is a very important question, primarily because we need to use one definition in order to be able to compare the prevalence of obesity in different countries. It is also important to have a single definition in order to evaluate whether interventions are successful or not.

31 Jul 2012

Rituximab aids remission in idiopathic membranous nephropathy

Rituximab achieves good rates of remission in patients with persistent idiopathic membranous nephropathy, with few serious adverse events, study results show.

31 Jul 2012

Researchers identify link between complete kidney removal and erectile dysfunction

Researchers at the University of California, San Diego School of Medicine have identified a link between patients who undergo total nephrectomy - complete kidney removal - and erectile dysfunction.

31 Jul 2012

Researchers identify new genetic target for diuretic therapy

Researchers at the University of Cincinnati (UC) have identified a new genetic target for diuretic therapy in patients with fluid overload-like those with congestive heart failure, liver cirrhosis or kidney failure.

31 Jul 2012

UTMB researchers receives NIH grant to develop engineered lung tissue for biomedical studies

University of Texas Medical Branch at Galveston researchers have been awarded a two-year, $1.25 million National Institutes of Health grant to develop a method of custom-growing human lung tissue to make a three-dimensional model for biomedical studies.

30 Jul 2012

Health systems must prepare for aging population living with HIV

"Many health systems are not ready to cope with the relatively new phenomenon" of people living with HIV (PLHIV) growing older, PlusNews reports. "Data on aging with HIV is largely restricted to the developed world and very little is known about older Africans living with virus, despite the high caseload in this region," the news service writes, adding, "A July 2012 supplement of the medical journal, AIDS, notes that an estimated three million people in sub-Saharan Africa aged 50 and older are HIV-positive -- 14 percent of all infected adults.

30 Jul 2012

Rituximab also benefits patients with kidney disorder

A drug commonly used to treat immune disorders such as lymphoma and arthritis also benefits patients with an immune disorder of the kidneys that can lead to kidney failure, according to a study appearing in an upcoming issue of new study in the Journal of the American Society of Nephrology (JASN).

28 Jul 2012

Kidney News and Research

TXNIP protein provides best available target for therapies against diabetes, Wolfram syndrome

Frailty may explain early dialysis initiation and mortality link

Less is definitely more for men who undergo nephrectomy

Potential new drug to treat common inherited kidney disease

Research roundup: Massachusetts health reform; Role of race and insurance in kidney transplantation

Depression in kidney cancer patients associated with survival and inflammatory gene regulation

Researchers discover surprising and unexpected plasticity in the embryonic endothelium

Iced tea can lead to formation of kidney stones

Weill Cornell Medical College receives NCATS grant to fund Clinical and Translational Science Center

Link between skeletal development and Fraser syndrome deafness in mammals

People with diabetes, hypertension and hyperlipidemia have difficultly managing all 3 conditions

Researchers discover new approach to treat two lethal metastatic cancers

Biomimetic bioartificial livers and cell toxicity assays: an interview with Dr. Joris Braspenning, CEO Medicyte

Obesity and heart disease risk in children: an interview with Joana Kist-van Holthe

Rituximab aids remission in idiopathic membranous nephropathy

Researchers identify link between complete kidney removal and erectile dysfunction

Researchers identify new genetic target for diuretic therapy

UTMB researchers receives NIH grant to develop engineered lung tissue for biomedical studies

Health systems must prepare for aging population living with HIV

Rituximab also benefits patients with kidney disorder

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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