Kidney News and Research

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Phosphate regulating hormone associated with increased risk of kidney failure and death among CKD patients

A high level of a hormone that regulates phosphate is associated with an increased risk of kidney failure and death among chronic kidney disease (CKD) patients, according to a recent study led by researchers at the University of Miami and funded by the National Institute of Diabetes and Digestive Diseases and Kidney Diseases (NIDDK) at the National Institutes of Health.

16 Jun 2011

Bristol-Myers Squibb receives FDA approval for Nulojix to prevent organ rejection after kidney transplant

The U.S. Food and Drug Administration today approved Nulojix to prevent acute rejection in adult patients who have had a kidney transplant. The drug is approved for use with other immunosuppressants -- specifically basiliximab, mycophenolate mofetil, and corticosteroids.

16 Jun 2011

Magnesium essential for absorption and metabolism of vitamin D and calcium

Magnesium deficiency is an important factor in the results obtained from vitamin D. According to Dr. Carolyn Dean, MD, ND, magnesium expert and Medical Director of the nonprofit Nutritional Magnesium Association, the effectiveness and benefits of vitamin D are greatly undermined in the absence of adequate levels of magnesium in the body.

15 Jun 2011

Overactive mTOR can result in serious disruption of kidney filter in diabetes patients

Diabetes mellitus is one of the most common secondary diseases in modern society. And because it is on the rise, it is also one of the greatest challenges facing medicine today. Diabetes patients do not die as a direct result of the increase in blood sugar, but from the long-term complications of their disease, in which the increase in blood sugar causes damage to blood vessels and organs.

15 Jun 2011

Childhood cancer survivors at increased risk of new cancers in middle age

CANCER RESEARCH UK scientists have found that survivors of childhood cancers are four times more likely than the general population to develop a new cancer. The results are published online today in JAMA.

15 Jun 2011

High FGF-23 hormone levels linked to increased risk of end-stage renal disease and death

Patients in the early stages of chronic kidney disease who had elevated levels of the endocrine hormone fibroblast growth factor 23 (that regulates phosphorus metabolism) had an associated increased risk of end-stage renal disease and death, according to a study in the June 15 issue of JAMA.

15 Jun 2011

CorMedix completes enrollment in CRMD001 Phase II trial for treatment of acute kidney injury

CorMedix Inc., a pharmaceutical company focused on developing and commercializing therapeutic products for the prevention and treatment of cardiorenal disease, announced it successfully completed patient enrollment in its phase II Contrast-Induced Acute Kidney Injury study with its oral drug candidate CRMD001.

14 Jun 2011

C-Path, IMI sign MoU to accelerate development of safer, more effective medicines for patients

Critical Path Institute (C-Path) and the Innovative Medicines Initiative (IMI) announced today that they have signed a Memorandum of Understanding (MoU) to further the missions of both organizations.

14 Jun 2011

Poor maternal nutrition predisposes offspring to type 2 diabetes

A new study published by the American Physiological Society offers the strongest evidence yet that vulnerability to type 2 diabetes can begin in the womb, giving new insight into the mechanisms that underlie a potentially devastating disease at the center of a worldwide epidemic.

14 Jun 2011

Calcium-sensing receptor plays key role in lethal lung cancer complication

A protein previously thought not to exist in adult human lungs not only is present in normal and cancerous lung tissue, scientists have found, but it also has a major role in the development of a lethal complication of some lung cancers.

14 Jun 2011

Mother to donate her womb to daughter

A 56-year-old mother hopes to become the first woman to have her womb transplanted into her daughter. Eva Ottoson who lives in Nottinghamshire has agreed to take part in the medical procedure that would see her donate her uterus to her daughter.

13 Jun 2011

Nose spray vaccine for type 1 diabetes could be a reality soon

Melbourne researchers are nearing the development of a vaccine for type 1 diabetes, after showing that a nasal spray can stop the body's immune system from attacking insulin-producing cells.

13 Jun 2011

Oncogene Aurora A may contribute to polycystic kidney disease

The Aurora A kinase may contribute to polycystic kidney disease (PKD) by inactivating a key calcium channel in kidney cells, according to a study in the June 13 issue of The Journal of Cell Biology.

13 Jun 2011

Policy issues related to dual-eligible patients, cancer medication coverage attract headlines

The Associated Press reports that seniors are facing Medicare cost barriers which sometimes lead them to not fill cancer drug prescriptions. Also, CQ HealthBeat reports that a special team within the Department of Health and Human Services is working on finding ways to save money and improve care for patients on both Medicare and Medicaid.

13 Jun 2011

Study reveals positive impact of Soliris on long-term outcomes in PNH patients

Alexion Pharmaceuticals, Inc. today announced the presentation of research that provides further insight into the clinical consequences of paroxysmal nocturnal hemoglobinuria (PNH), and positive impact of Soliris® (eculizumab) therapy on long-term outcomes.

13 Jun 2011

HHS adds eight substances to 12th Report on Carcinogens

The U.S. Department of Health and Human Services added eight substances to its Report on Carcinogens, a science-based document that identifies chemicals and biological agents that may put people at increased risk for cancer.

13 Jun 2011

Only 35% of anaesthesiologists carry out cardiac output monitoring during high-risk surgery

Only 35% of anaesthesiologists are carrying out a simple procedure during high-risk surgery that can make a significant impact on how well patients recover from their operations, according to new research presented today at the European Anaesthesiology Congress in Amsterdam.

13 Jun 2011

Final data from Alexion's Soliris Phase 2 studies on aHUS presented at EHA 2011

Alexion Pharmaceuticals, Inc. today announced the presentation of final data from the two Phase 2 studies of Soliris as a treatment for patients with atypical hemolytic uremic syndrome.

13 Jun 2011

NIH awards $1.9M grant to Scripps Research scientist for malaria study

A scientist from The Scripps Research Institute has won a four-year, $1.9 million grant from the National Institutes of Health to better understand the parasite that causes malaria, laying the groundwork to develop better drugs to combat the widespread and deadly disease.

10 Jun 2011

IBC now qualified as 'patient-centered medical homes'

Independence Blue Cross (IBC) has reached a significant milestone with 100 primary care practices with more than 1,000 physicians now qualified as "patient-centered medical homes," and announced today that it is stepping up its efforts to support this transformation of primary care.

10 Jun 2011

Kidney News and Research

Phosphate regulating hormone associated with increased risk of kidney failure and death among CKD patients

Bristol-Myers Squibb receives FDA approval for Nulojix to prevent organ rejection after kidney transplant

Magnesium essential for absorption and metabolism of vitamin D and calcium

Overactive mTOR can result in serious disruption of kidney filter in diabetes patients

Childhood cancer survivors at increased risk of new cancers in middle age

High FGF-23 hormone levels linked to increased risk of end-stage renal disease and death

CorMedix completes enrollment in CRMD001 Phase II trial for treatment of acute kidney injury

C-Path, IMI sign MoU to accelerate development of safer, more effective medicines for patients

Poor maternal nutrition predisposes offspring to type 2 diabetes

Calcium-sensing receptor plays key role in lethal lung cancer complication

Mother to donate her womb to daughter

Nose spray vaccine for type 1 diabetes could be a reality soon

Oncogene Aurora A may contribute to polycystic kidney disease

Policy issues related to dual-eligible patients, cancer medication coverage attract headlines

Study reveals positive impact of Soliris on long-term outcomes in PNH patients

HHS adds eight substances to 12th Report on Carcinogens

Only 35% of anaesthesiologists carry out cardiac output monitoring during high-risk surgery

Final data from Alexion's Soliris Phase 2 studies on aHUS presented at EHA 2011

NIH awards $1.9M grant to Scripps Research scientist for malaria study

IBC now qualified as 'patient-centered medical homes'

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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