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FDA authorizes Juventas' JVS-100 Phase II clinical trial for critical limb ischemia

Juventas Therapeutics, a clinical-stage regenerative medicine company developing novel therapies for cardiovascular disease, announces that the U.S. Food and Drug Administration (FDA) authorized commencement of a Phase II clinical trial evaluating the efficacy and safety of its lead product, JVS-100, for the treatment of critical limb ischemia (CLI).

3 Jan 2011

Flu worries continue

As number of cases of flu rise in the UK, Health Secretary Andrew Lansley is under pressure to strengthen the flu vaccination campaign. He reinstated a public health “Catch It, Bin It, Kill It” advertising campaign after he was warned by government advisers of the need to improve immunization rates which are at their lowest this winter for many years. It had been discontinued despite helping educate the public to adopt good hygiene habits during last year’s H1N1 swine flu epidemic at a cost of just £609,000. There were 12 more deaths in the last week from flu, bringing the total this winter to 39, the Health Protection Agency (HPA) said today. Thirty-six were killed by H1N1 swine flu, which is the most virulent of the two main flu strains currently circulating. The others died after contracting Influenza B, the other strain. All except one of the 39 were under 65 and four were under five.

2 Jan 2011

World’s first organ donor dies at 79

On December 23, 1954, Dr. Joseph Murray performed the world’s first kidney transplant removing a kidney from Ronald Herrick and implanting it in his identical twin Richard. Years later, Murray shared a Nobel Prize for his groundbreaking work. For the Herrick twins, the results were more immediate and personal. Richard lived for about eight more years because of Ronald’s donation.

30 Dec 2010

Researchers study molecular mechanisms in early stages of IPN virus infection

Infectious pancreatic necrosis is a serious disease that leads to enormous losses in the salmon industry each year. The virus that causes the disease, IPN, is very prevalent in farmed salmon and trout in Norway. The virus attacks a wide diversity of hosts and has been found to occur in many different fish species, in addition to shellfish and molluscs.

30 Dec 2010

Patients unresponsive to anti-anemia drug have higher risk of cardiovascular disease, death

Patients with diabetes, kidney disease and anemia who don't respond to treatment with an anti-anemia drug have a higher risk of cardiovascular disease or death, researchers at UT Southwestern Medical Center have found.

28 Dec 2010

Hormone enhanced meat taken off shelves at Coles

Hormonal growth enhancers banned three decades ago in Europe after being linked to health risks including breast cancer, kidney disease and birth defects are still being used in Australia to fatten beef, a federal farm chemical survey reveals.

28 Dec 2010

Biglycan protein offers potential therapy for muscular dystrophy

A novel potential therapy based on a natural human protein significantly slows muscle damage and improves function in mice who have the same genetic mutation as boys with the most common form of muscular dystrophy, according to a paper published online Dec. 27 in the Proceedings of the National Academy of Sciences.

28 Dec 2010

Gold-coated liposomes could make chemotherapy more effective without harmful side effects

University of Arizona researchers may have found a way to deliver chemotherapeutic drugs to cancer tissues in controlled doses without harming healthy body cells.

24 Dec 2010

New derivation of stem cells from fat cells hold promise for therapeutic, cosmetic benefits

Two studies appearing in the current issue of Cell Transplantation 19(10) discuss stem cells derived from adipose (fat) cells and their potential use in plastic surgery and tissue reconstruction. The studies are now freely available on-line at http://www.ingentaconnect.com/content/cog/ct/ .

24 Dec 2010

Study shows vegetarian diet lowers blood, urine phosphorous levels

Phosphorous levels plummet in kidney disease patients who stick to a vegetarian diet, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society Nephrology. The results suggest that eating vegetables rather than meat can help kidney disease patients avoid accumulating toxic levels of this mineral in their bodies.

24 Dec 2010

Jury returns $7M verdict for failure to diagnose and treat cardiac tamponade in bypass surgery patient

A New York State Supreme Court Queens County jury returned a $7,000,000.00 verdict against Patrick Monteleone M.D. and Newell Robinson, M.D. where they failed to diagnose and treat cardiac tamponade (bleeding into the chest) in their patient who underwent cardiac bypass surgery on November 17, 2004.

23 Dec 2010

Earlier diagnosis in Cowden syndrome patients predisposed to breast and kidney cancer

Researchers at Cleveland Clinic's Genomic Medicine Institute have revealed multiple genetic discoveries that may permit easier diagnosis and disease management for Cowden syndrome patients who are predisposed to breast and kidney cancer.

23 Dec 2010

New study reveals statin therapy linked to reduced postoperative mortality

Statin drugs were first introduced to lower blood cholesterol concentrations; however, research is now discovering other benefits. A new study from France, published in the January 2011 issue of Anesthesiology, is the first to analyze the impact of preoperative chronic statin therapy on postoperative adverse events in surgical patients. Findings from the study suggest that statin therapy is associated with reduced postoperative mortality.

23 Dec 2010

Researchers identify class of drugs that can promote RBC formation in anemic patients

By determining how corticosteroids act to promote red blood cell progenitor formation, Whitehead Institute researchers have identified a class of drugs that may be beneficial in anemias, including those resulting from trauma, sepsis, malaria, kidney dialysis, and chemotherapy.

22 Dec 2010

Top ten advances in cardiovascular, stroke research in 2010

Research on reducing risks, improving medical treatment and improving lifestyle behaviors to fight the battle against heart disease and stroke are among the key scientific findings that make up this year's top cardiovascular and stroke research recognized by the American Heart Association/American Stroke Association.

22 Dec 2010

Pepex announces development of combined glucose monitoring and insulin delivery meter

Pepex Biomedical, Inc. has unveiled development of a next generation solution for insulin dependent diabetics which will combine regular glucose monitoring and insulin delivery for diabetes sufferers worldwide. The company is developing a complete product line of multi-function meters which allow simple testing of blood glucose levels and insulin delivery, appropriate to each glucose level measurement, all contained in a single, palm-sized unit. These meters provide anytime, anywhere tracking and treatment of diabetes.

22 Dec 2010

New genetic alteration predisposes individuals to Cowden syndrome

Researchers have identified a new genetic alteration that predisposes individuals to Cowden syndrome, a rare disorder that is characterized by high risks of breast, thyroid and other cancers, according to preliminary research published in the December 22/29 issue of JAMA.

21 Dec 2010

Amylin submits metreleptin rolling submission BLA for treatment of rare forms of lipodystrophy

Amylin Pharmaceuticals, Inc. today announced that it has submitted the initial sections of a rolling submission for a Biologics License Application (BLA) to the U.S. Food and Drug Administration (FDA) for the use of metreleptin to treat diabetes and/or hypertriglyceridemia (high levels of triglycerides in the bloodstream) in patients with rare forms of lipodystrophy.

21 Dec 2010

FMCNA recommends dialysis patients to take precautions during severe weather

Fresenius Medical Care North America, the nation's leading network of dialysis facilities, reminds dialysis patients to take precautions now so they are not caught off guard when severe weather hits in their home community.

21 Dec 2010

Silence provides year-end update on trading and offer-period

Silence Therapeutics plc, a leading global biotechnology company dedicated to the discovery, development and delivery of targeted, systemic RNA interference (RNAi) therapeutics for the treatment of serious diseases, today provides a year-end update on trading and the offer-period.

21 Dec 2010

Kidney News and Research

FDA authorizes Juventas' JVS-100 Phase II clinical trial for critical limb ischemia

Flu worries continue

World’s first organ donor dies at 79

Researchers study molecular mechanisms in early stages of IPN virus infection

Patients unresponsive to anti-anemia drug have higher risk of cardiovascular disease, death

Hormone enhanced meat taken off shelves at Coles

Biglycan protein offers potential therapy for muscular dystrophy

Gold-coated liposomes could make chemotherapy more effective without harmful side effects

New derivation of stem cells from fat cells hold promise for therapeutic, cosmetic benefits

Study shows vegetarian diet lowers blood, urine phosphorous levels

Jury returns $7M verdict for failure to diagnose and treat cardiac tamponade in bypass surgery patient

Earlier diagnosis in Cowden syndrome patients predisposed to breast and kidney cancer

New study reveals statin therapy linked to reduced postoperative mortality

Researchers identify class of drugs that can promote RBC formation in anemic patients

Top ten advances in cardiovascular, stroke research in 2010

Pepex announces development of combined glucose monitoring and insulin delivery meter

New genetic alteration predisposes individuals to Cowden syndrome

Amylin submits metreleptin rolling submission BLA for treatment of rare forms of lipodystrophy

FMCNA recommends dialysis patients to take precautions during severe weather

Silence provides year-end update on trading and offer-period

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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