Kidney Transplant News and Research

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A kidney transplant is an operation where a healthy kidney from one person (the donor) is transferred to a person who has little or no kidney function (the recipient).

National task force advocates removal of race from the kidney function algorithm

A national task force announced Thursday that it is recommending the immediate implementation of a new diagnostic equation for measuring kidney function, which advocates say will promote health equity and increase access to transplantation for Black patients.

24 Sep 2021

Higher-rated dialysis facilities yield a 47% higher likelihood of transplant waitlisting for patients

Dialysis centers, the gatekeepers of kidney transplantation waitlisting, produce more data and inspire more policies today than ever before.

24 Sep 2021

Results from Phase 0/1 trial of ribociclib plus everolimus in patients with high-grade glioma announced

The Ivy Brain Tumor Center at Barrow Neurological Institute, the largest early-phase drug development program for brain cancer in the world, announced results from their Phase 0/1 clinical trial of ribociclib plus everolimus in patients with high-grade glioma (HGG).

13 Sep 2021

Study offers important evidence for the safety of stem cell transplants

Stem cell transplants do not lead to changes in the DNA of the donor cells. That's according to a new study, which provides important evidence for the safety of this procedure.

7 Sep 2021

COVID-19 associated with increased risk of kidney damage, end-stage kidney diseases

A study by researchers at Washington University School of Medicine in St. Louis and the Veterans Affairs St. Louis Health Care System shows that people who have had COVID-19, including those with mild cases, are at an increased risk of developing kidney damage as well as chronic and end-stage kidney diseases.

1 Sep 2021

Do kidney transplant recipients need a third booster dose of mRNA COVID-19 vaccine?

A team of researchers in France have observed that the “standard” 2 dose regimen for mRNA COVID-19 vaccines could provide adequate protection to only a few KTRs. It has also been shown in multiple studies that a considerable population of vaccinated KTRs were easily infected with SARS-CoV-2.

1 Sep 2021

Severe COVID-19 negatively impacts kidney function in kidney transplant recipients

During her medical school career, third-year student Skylar Nahi has taken advantage of the mentorship and research opportunities available to Feinberg students.

31 Aug 2021

'Humanized' mouse model beats current approaches for finding the best organ donor

A "humanized" mouse model equipped with the immune system of a patient who needs an organ transplant beats current measures for identifying the best potential living donor, scientists report.

27 Aug 2021

Cancer linked with increased risk of kidney failure

Previous studies have shown an increased cancer risk within the dialysis and kidney transplant populations compared to the general population. However, it is unclear whether cancer increases the risk of kidney failure.

18 Aug 2021

Response to a third SARS-CoV-2 vaccine dose amongst immunocompromised

In a research paper recently uploaded to the preprint server medRxiv* by Schrezenmeier et al. (August 12th, 2021) the potential benefit of three vaccine doses in either a homogenous or heterogeneous dosing regimen amongst kidney transplant patients is assessed, finding that the search for viable vaccination approaches amongst these patients remains an urgent medical need.

16 Aug 2021

‘I don’t want to risk my life for a paycheck’: Immunosuppressed people grapple with returning to work

Elizabeth Groenweghe got a kidney transplant 14 years ago. She now takes several medications to prevent her body from rejecting her transplant organ. But these medications also weaken her immune system, putting her at higher risk of becoming seriously ill if she catches covid-19.

13 Aug 2021

Pilot study assesses antibody response to third COVID-19 vaccine dose in kidney transplant recipients

A pilot study has begun to assess the antibody response to a third dose of an authorized COVID-19 mRNA vaccine in kidney transplant recipients who did not respond to two doses of the Moderna or Pfizer-BioNTech COVID-19 vaccine.

10 Aug 2021

Polymer-based coating for blood vessels can reduce organ rejection following a transplant

Researchers have found a way to reduce organ rejection following a transplant by using a special polymer to coat blood vessels on the organ to be transplanted.

9 Aug 2021

COVID-19 vaccination offers significant protection for solid organ transplant recipients

In a Brief Communication, published July 29, 2021 in the journal Transplant Infectious Disease, a team of physician-scientists at University of California San Diego School of Medicine found that solid organ transplant recipients who were vaccinated experienced an almost 80 percent reduction in the incidence of symptomatic COVID-19 compared to unvaccinated counterparts during the same time.

5 Aug 2021

Artificial pancreas may soon help patients with type 2 diabetes

An artificial pancreas could soon help people living with type 2 diabetes and who also require kidney dialysis. Tests led by the University of Cambridge and Inselspital, University Hospital of Bern, Switzerland, show that the device can help patients safely and effectively manage their blood sugar levels and reduce the risk of low blood sugar levels.

4 Aug 2021

Immunity to SARS-CoV-2 in renal transplant and dialysis patients using Pfizer/BioNTech and Moderna vaccines

A study analyzes the immune responses of medical personnel, as well as immunocompromised DP and immunosuppressed KTR patients.

27 Jul 2021

The impact of COVID-19 on dialysis patients

In this interview, News-Medical speaks to Professor Simon Davies and Dr. Raymond Vanholder about the impact of COVID-19 on kidney dialysis patients.

1 Jul 2021

Analysis of COVID-19 patients with repeatedly positive SARS-CoV-2 tests

New research published on the medRxiv preprint server provides a detailed analysis of COVID-19 patients who had repeated positive PCR tests for SARS-CoV-2 infection in a large US COVID-19 electronic health record (EHR) database.

15 Jun 2021

Kidney experts say it’s time to remove race from medical algorithms. Doing so is complicated.

Alphonso Harried recently came across a newspaper clipping about his grandfather receiving his 1,000th dialysis treatment. His grandfather later died — at a dialysis center — as did his uncle, both from kidney disease.

8 Jun 2021

Melatonin prevents kidney damage caused by metabolic complications of obesity

Scientists from the University of Granada (UGR), the Hospital Universitario La Paz (Madrid), and the University of Texas (USA) have taken an important step in the fight against kidney damage and its progression towards kidney failure, which is closely related to diabesity (obesity and its type 2 diabetes) and its complications.

27 May 2021