Kinase News and Research

RSS

Newly discovered protein kinase shows promise for establishing future obesity and diabetes treatments

Researchers used genetically modified animal models to investigate the role of the newly discovered Traf2- and NCK-interacting protein kinase (TNIK) in obesity and metabolic dysfunction.

15 Aug 2023

The role of estrogen in osteoarthritis and lower back pain

Researchers review existing evidence on the association between estrogen, osteoarthritis, and lower back pain.

10 Aug 2023

Exploring molecular mechanisms and genetic dysregulation in aging and age-associated diseases

Researchers review existing data on the molecular basis of senescence and neurodegeneration in age-related brain diseases.

10 Aug 2023

How conversion between different types of cell death contributes to disease

Researchers elucidate the role of cell death in the pathogenesis of different diseases.

10 Aug 2023

What are some recent advancements in proteomics-driven pancreatic oncology research?

The application of proteomics-driven biomarkers for early detection, diagnosis, and treatment of pancreatic cancer.

9 Aug 2023

The impact of epigenetic features on breast cancer treatment and outcomes

The impact of epigenetic features on breast cancer treatment and outcomes.

9 Aug 2023

Identification of plasma proteins associated with ovarian cancer risk

Researchers performed proteomic Mendelian randomization as well as co-localization analyses to identify drug targets for ovarian cancer.

8 Aug 2023

The green tea effect: From gut microbes to weight loss, new insights emerge

The impact of green tea and its functional components on body weight and gut microbiota regulation.

8 Aug 2023

Childhood abuse can induce stress that changes neural networks and functions during growth

Childhood neglect and/or abuse can induce extreme stress that significantly changes neural networks and functions during growth. This can lead to mental illnesses, including depression and schizophrenia, but the exact mechanism and means to control it were yet to be discovered.

4 Aug 2023

Recent advances in the understanding of the role and mechanism of CCAR2 in cancer

Researchers described the dual role of cell cycle and apoptosis regulator 2 (CCAR2) in cancer progression as a tumor suppressor and promoter.

4 Aug 2023

Research sheds light on the causes of endometriosis-related pelvic pain

Pelvic pain in women with endometriosis is attributed to neuroinflammation. Researchers investigated biochemical mediators of endometriosis-associated pelvic pain to provide a foundation to identify new drugs to improve symptoms and quality of life.

3 Aug 2023

Reversing β-cell failure: A promising approach for type 2 diabetes treatment

Researchers examined current evidence on the reasons and implications of pancreatic beta-cell failure.

3 Aug 2023

Insilico Medicine uses AI to discover novel SIK2 inhibitors

Insilico Medicine ("Insilico"), a clinical-stage end-to-end generative artificial intelligence (AI) drug discovery company, has achieved a significant breakthrough in the application of multiple generative AI models and AlphaFold structures for drug discovery.

2 Aug 2023

Molecular insights into drug-induced GDF15 regulation in cancer cells and cardiomyocytes: implications for precision medicine

A recent study elucidated the molecular mechanisms of drug-induced regulation of growth differentiation factor 15 (GDF15).

1 Aug 2023

Two new compounds can block cancer cell’s escape route

Cancer cells are capable of escaping chemotherapy and radiotherapy by activating a signaling pathway that prevents them from dying.

27 Jul 2023

Positive experiences can reverse cognitive decline in old age

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 13, entitled, "MSK1 is required for the beneficial synaptic and cognitive effects of enriched experience across the lifespan."

26 Jul 2023

Addressing research gaps: The UK's efforts to study lung cancer in never smokers

Study aimed to understand the specific needs of lung cancer in never smokers (LCINS) patients.

25 Jul 2023

Could alpha lipoic acid treat polycystic ovary syndrome?

Authors analyzed the efficacy of alpha lipoic acid (ALA) in treating polycystic ovary syndrome (PCOS).

24 Jul 2023

KIPA shows promise in predicting chemotherapy response in triple negative breast cancer

Researchers at Baylor College of Medicine and collaborating institutions are developing a strategy to predict the response of triple negative breast cancer (TNBC) to chemotherapy, which would be a valuable tool for physicians deciding on the treatment with better probability of success on an individual basis.

21 Jul 2023

ECOG-ACRIN launches new trial to evaluate nilotinib and paclitaxel for advanced cancers

The ECOG-ACRIN Cancer Research Group has enrolled the first patient in a new treatment trial to evaluate the effectiveness of adding nilotinib to standard paclitaxel chemotherapy.

20 Jul 2023

Kinase News and Research

Newly discovered protein kinase shows promise for establishing future obesity and diabetes treatments

The role of estrogen in osteoarthritis and lower back pain

Exploring molecular mechanisms and genetic dysregulation in aging and age-associated diseases

How conversion between different types of cell death contributes to disease

What are some recent advancements in proteomics-driven pancreatic oncology research?

The impact of epigenetic features on breast cancer treatment and outcomes

Identification of plasma proteins associated with ovarian cancer risk

The green tea effect: From gut microbes to weight loss, new insights emerge

Childhood abuse can induce stress that changes neural networks and functions during growth

Recent advances in the understanding of the role and mechanism of CCAR2 in cancer

Research sheds light on the causes of endometriosis-related pelvic pain

Reversing β-cell failure: A promising approach for type 2 diabetes treatment

Insilico Medicine uses AI to discover novel SIK2 inhibitors

Molecular insights into drug-induced GDF15 regulation in cancer cells and cardiomyocytes: implications for precision medicine

Two new compounds can block cancer cell’s escape route

Positive experiences can reverse cognitive decline in old age

Addressing research gaps: The UK's efforts to study lung cancer in never smokers

Could alpha lipoic acid treat polycystic ovary syndrome?

KIPA shows promise in predicting chemotherapy response in triple negative breast cancer

ECOG-ACRIN launches new trial to evaluate nilotinib and paclitaxel for advanced cancers

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

Latest News