Knee Replacement News and Research

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Phase 2 dose-ranging study of AYX1 for prevention of post-surgical pain

Adynxx, developer of a first-in-class platform of therapeutics to address pain at its molecular roots, announced today that the first patient was dosed in ADYX-003, a Phase 2 dose-ranging study of AYX1, an investigational drug candidate for the prevention of post-surgical pain.

17 Jul 2014

New analysis provides information about which medications best after different types of surgery

Current guidelines do not distinguish between aspirin and more potent blood thinners for protecting against blood clots in patients who undergo major orthopedic operations, leaving the decision up to individual clinicians.

17 Jul 2014

Complications from partial knee replacement is very small than total knee replacement

Partial knee replacement surgery is safer than total knee replacement, according to a new study published in The Lancet today (July 8).

8 Jul 2014

Orthopedic surgeon offers critical insights on total knee replacement surgery

In 2010, Bonnie Egbert, a veteran of more than 20 marathons, had to quit running due to excruciating pain caused by her right knee joint rubbing bone on bone.

4 Jul 2014

Modified classification system finds over one-third of knee replacements as inappropriate

New research reports that more than one third of total knee replacements in the U.S. were classified as "inappropriate" using a patient classification system developed and validated in Spain. The study, published in Arthritis & Rheumatology, a journal of the American College of Rheumatology (ACR), highlights the need for consensus on patient selection criteria among U.S. medical professionals treating those with the potential need of knee replacement surgery.

30 Jun 2014

Researchers find differences between hip and knee replacement surgeries in USA and Germany

Researchers used individual inpatient data from Germany and the USA to investigate changes over time and differences between 2005 and 2011. In 2011, 284 hip replacements were performed per 100 000 population in Germany, while 204 were performed per 100 000 population in the USA.

26 Jun 2014

State highlights: State retiree benefit shortfalls; health data claims and cost

A selection of health policy stories from California, Maine, Massachusetts, Maryland, New Hampshire, Virginia, Iowa, Florida, Missouri, Washington state, Connecticut, Georgia, Alabama, North Carolina and Tennessee.

18 Jun 2014

iGetBetter selects Validic platform to access data from broad range of biometric devices

iGetBetter, Inc., a supplier of post-acute care transition solutions, and Validic, the healthcare industry's premier technology platform for accessing digital health data, announced today that iGetBetter has selected the Validic platform to access data from a broad range of available biometric devices as part of its care transition solution focused on reducing readmissions.

10 Jun 2014

European Commission approves Boehringer Ingelheim's Pradaxa for prevention of DVT and PE

Boehringer Ingelheim today announces that Pradaxa (dabigatran etexilate) has been approved by the European Commission for the treatment and prevention of recurrence of deep vein thrombosis (DVT) and pulmonary embolism (PE).

6 Jun 2014

Highlights: Calif. insurance commissioner battle; food stamps and Medicaid in Calif.; Mo. and experimental drug therapies

Incumbent Democrat Dave Jones held a strong lead in Tuesday's primary election voting for state insurance commissioner, but he still faces a rematch in November against Republican challenger Ted Gaines (Lifsher, 6/3).

5 Jun 2014

ConforMIS announces positive study results of iTotal implant at BASK meeting

ConforMIS, Inc., a medical device company pioneering patient-specific orthopaedic implants, today announced results from several clinical research studies highlighting the benefits of the iTotal® patient-specific total knee replacement.

4 Jun 2014

Ultrasound beam 'tweezers' can grip and manipulate tiny clusters of cells

Pioneering 'tweezers' that use ultrasound beams to grip and manipulate tiny clusters of cells under electronic, push-button control could lead to life-changing medical advances, such as better cartilage implants that reduce the need for knee replacement operations.

31 May 2014

Medicare intends to penalize hospitals for giving followup care to seniors

Medicare has announced plans to penalize 2,633 hospitals for giving followup care to seniors, even if the care was appropriate.

30 May 2014

Nerve block technique offers potentially speedier recovery for orthopedic surgery patients

A Virginia Mason study has determined that a nerve block technique which avoids the femoral nerve results in the need for less morphine and a potentially speedier recovery for orthopedic surgery patients.

30 May 2014

Active Implants receives IDE approval to conduct NUsurface Meniscus Implant trial for knee osteoarthritis

Active Implants, the technology leader in cushion-bearing orthopedics for treatment of osteoarthritis, today announced it has received Investigational Device Exemption (IDE) approval to conduct a pivotal clinical trial of the NUsurface® Meniscus Implant in patients with knee osteoarthritis.

30 May 2014

Obesity linked with longer hospital stays and higher costs in TKR patients

Obesity is associated with longer hospital stays and higher costs in total knee replacement (TKR) patients, independent of whether or not the patient has an obesity-related disease or condition (comorbidity), according to a new study published in the Journal of Bone and Joint Surgery (JBJS).

15 May 2014

Isis Pharmaceuticals reports pro forma net operating loss of $22.6 million for Q1 2014

Isis Pharmaceuticals, Inc. today reported a pro forma net operating loss (NOL) of $22.6 million for the three months ended March 31, 2014 compared to pro forma operating income of $4.5 million for the same period in 2013.

6 May 2014

Standard test that measures everyday activities may help prevent rapid return to inpatient care

Patients freshly discharged from acute care hospitals with low scores on a standard test that measures how well they perform such everyday activities as moving from a bed to a chair are far more likely to need readmission to a hospital within 30 days than those who score better, according to new Johns Hopkins research.

6 May 2014

Research grants could improve patients' recovery from athletic and nonathletic injuries

Two orthopedic organizations have presented Beaumont Health System with prestigious, competitive research grants that could improve patients' recovery from both athletic and nonathletic injuries.

23 Apr 2014

Research roundup: Colonscopy in the countryside; retiree health benefits; what should hip surgery cost?

Rural residents who commonly seek treatment for advanced stages of colorectal cancer have been thought to lack access to cancer screening and adjuvant therapy. ... Several theories have been postulated to explain these findings, some of which include low socioeconomic status, lower educational attainment, lack of insurance coverage, underinsurance, and travel distance to health care facilities.

21 Apr 2014

Knee Replacement News and Research

Phase 2 dose-ranging study of AYX1 for prevention of post-surgical pain

New analysis provides information about which medications best after different types of surgery

Complications from partial knee replacement is very small than total knee replacement

Orthopedic surgeon offers critical insights on total knee replacement surgery

Modified classification system finds over one-third of knee replacements as inappropriate

Researchers find differences between hip and knee replacement surgeries in USA and Germany

State highlights: State retiree benefit shortfalls; health data claims and cost

iGetBetter selects Validic platform to access data from broad range of biometric devices

European Commission approves Boehringer Ingelheim's Pradaxa for prevention of DVT and PE

Highlights: Calif. insurance commissioner battle; food stamps and Medicaid in Calif.; Mo. and experimental drug therapies

ConforMIS announces positive study results of iTotal implant at BASK meeting

Ultrasound beam 'tweezers' can grip and manipulate tiny clusters of cells

Medicare intends to penalize hospitals for giving followup care to seniors

Nerve block technique offers potentially speedier recovery for orthopedic surgery patients

Active Implants receives IDE approval to conduct NUsurface Meniscus Implant trial for knee osteoarthritis

Obesity linked with longer hospital stays and higher costs in TKR patients

Isis Pharmaceuticals reports pro forma net operating loss of $22.6 million for Q1 2014

Standard test that measures everyday activities may help prevent rapid return to inpatient care

Research grants could improve patients' recovery from athletic and nonathletic injuries

Research roundup: Colonscopy in the countryside; retiree health benefits; what should hip surgery cost?

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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