Knee Replacement News and Research

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Hydrocortisone protects bilateral knee replacement patients

Repeat doses of corticosteroids may protect patients undergoing bilateral total knee arthroplasty from postoperative side effects such as fever, pain, and acute respiratory distress, research suggests.

16 Nov 2012

First HSS medical symposium to take place in Rio de Janeiro from Nov. 28-29

The first medical symposium in Brazil presented by Hospitalys Ortopedia in Rio de Janeiro and New York City's Hospital for Special Surgery (HSS) will take place November 28 and 29 in Rio de Janeiro.

16 Nov 2012

Patients more likely to develop ischemic stroke after total hip replacement surgeries

An international study involving the University of Southampton has shown people who undergo a total hip replacement are at a higher risk of a stroke in the first two weeks after surgery.

9 Nov 2012

Pay-for-performance schemes may help save lives of NHS patients

New research into controversial pay-for-performance schemes has suggested they may help to save the lives of NHS patients.

From The University of Manchester 8 Nov 2012

Bristol-Myers Squibb, Pfizer and Portola partner to conduct clinical study of PRT4445 and ELIQUIS

Portola Pharmaceuticals, Inc., Bristol-Myers Squibb Company and Pfizer Inc. today announced a clinical collaboration agreement to conduct a proof-of-concept study of PRT4445 and the investigational oral Factor Xa inhibitor ELIQUIS (apixaban).

3 Nov 2012

Pfizer, Bristol-Myers Squibb announce data from ELIQUIS clinical trial on AF

Bristol-Myers Squibb Company and Pfizer Inc. today announced that a large number of data presentations sponsored by the companies on ELIQUIS (apixaban) and the treatment of atrial fibrillation will be presented at the American Heart Association 2012 Scientific Sessions, November 3-7, 2012, in Los Angeles, California.

3 Nov 2012

Regional anesthesia reduces transfusion risk in knee replacement surgery

Regional anesthesia, compared with general anesthesia, reduces the need for blood transfusions in patients undergoing bilateral total knee replacement, research suggests.

31 Oct 2012

Isis commences ISIS-FXIRx Phase 2 study in knee replacement surgery patients

Isis Pharmaceuticals, Inc. announced the initiation of a Phase 2 comparator-controlled study evaluating ISIS-FXIRx in patients undergoing knee replacement surgery, also referred to as total knee arthroplasty (TKA).

29 Oct 2012

Neuraxial anesthesia should be promoted for bilateral total knee replacements: HSS

Using regional anesthesia rather than general anesthesia reduces the need for blood transfusions in patients undergoing bilateral total knee replacement, according to a new study by researchers at Hospital for Special Surgery, in New York City.

29 Oct 2012

Obese patients more likely to have complications after total knee replacement surgery

Obese patients have a greater risk of complications following total knee replacement surgery, including post-surgical infections, according to a new literature review recently published in the Journal of Bone and Joint Surgery (JBJS).

25 Oct 2012

Non-surgical orthopedic medical devices: an interview with Brian Moore, Director of Sales and Product Marketing from DJO global

Non-surgical orthopedic medical devices are products designed to help relieve pain in specific parts of the body.

10 Oct 2012

Research roundup: Saving money with hospital observation units, total knee replacement rates skyrocketing, Medicare patients and antibiotic overuse

The authors write: Using observation units in hospitals to provide care to certain patients can be more efficient than admitting them to the hospital and can result in shorter lengths-of-stay and lower costs. However, such units are present in only about one-third of US hospitals.

29 Sep 2012

Pfizer, Bristol-Myers Squibb report FDA acknowledgement of ELIQUIS NDA resubmission

Bristol-Myers Squibb Company and Pfizer Inc. today announced that the U.S. Food and Drug Administration (FDA) has acknowledged receipt of the New Drug Application (NDA) resubmission for ELIQUIS (apixaban) to reduce the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation (NVAF).

27 Sep 2012

Study finds increase in number of total knee replacements among U.S. Medicare population

Total knee replacement is a very common and safe surgery that's used to relieve severe pain and disability caused by knee osteoarthritis, and to improve patients' quality of life. However, it's also very expensive at approximately $15,000 per procedure. With an estimated 600,000 total knee replacements performed annually in the United States, the aggregate annual cost for total knee replacement (also known as total knee arthroplasty or TKA) is $9 billion.

27 Sep 2012

EMA CHMP adopts positive opinion for ELIQUIS to prevent stroke, systemic embolism in NVAF patients

Bristol-Myers Squibb and Pfizer Inc. today announced that the Committee for Medicinal Products for Human Use of the European Medicines Agency has adopted a positive opinion recommending that ELIQUIS (apixaban) be granted approval for the prevention of stroke and systemic embolism in adult patients with nonvalvular atrial fibrillation (NVAF) and one or more risk factors for stroke.

21 Sep 2012

Study of spinal injury data may help surgeons treat injured soldiers or civilians

Spinal injuries are among the most disabling conditions affecting wounded members of the U.S. military. Yet until recently, the nature of those injuries had not been adequately explored.

21 Sep 2012

Apixaban offers minor added benefit for adult patients after hip replacement

The clot-inhibiting drug apixaban was approved in May 2011 for the prevention of thrombosis (blood clots) after operations to replace a hip or knee joint.

18 Sep 2012

More patients gain weight after joint replacement surgery

Hip and knee replacements are now a common surgical procedure with more than 700,000 total joint arthroplasties (TJAs) performed in the US every year. Due to the reduction in pain and increases in mobility experienced after having a TJA, it could be expected that weight loss may occur as a by-product of the surgery.

10 Sep 2012

Obesity no barrier to knee replacement surgery

Health policy should not withhold total knee arthroplasty from patients on the basis of obesity, say UK researchers.

3 Sep 2012

Some smaller clots may not require potentially risky treatment

Men and women who undergo joint replacement procedures, as well as those who have significant fractures, tend to be at an increased risk of developing pulmonary emboli (PE), blood clots that travel to the lungs where they may cause serious complications and even death.

1 Sep 2012